A thymidine triphosphate shape analog lacking Watson–Crick pairing ability is replicated with high sequence selectivity

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

1991 • 2,172 citations

FIDELITY MECHANISMS IN DNA REPLICATION

1991 • 709 citations

How good is fluorine as a hydrogen bond acceptor?

1996 • 694 citations

Fidelity of DNA Synthesis

1982 • 516 citations

Biochemical Basis of DNA Replication Fidelity

1993 • 441 citations

Conversion of Mono- and Oligodeoxyribonucleotides to 5'-Triphosphates¹

1965 • 428 citations

Oligodeoxynucleotides containing synthetic abasic sites. Model substrates for DNA polymerases and apurinic/apyrimidinic endonucleases.

1987 • 399 citations

Kinetic mechanism of DNA polymerase I (Klenow)

1987 • 352 citations

Molecular biology of the gene

1988 • 348 citations

DNA polymerase insertion fidelity. Gel assay for site-specific kinetics.

1987 • 332 citations

Insertion of nucleotides opposite apurinic apyrimidinic sites in deoxyribonucleic acid during in vitro synthesis: uniqueness of adenine nucleotides

1983 • 320 citations

Comparison between DNA melting thermodynamics and DNA polymerase fidelity.

1988 • 319 citations

Difluorotoluene, a Nonpolar Isostere for Thymine, Codes Specifically and Efficiently for Adenine in DNA Replication

1997 • 314 citations

Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme

1987 • 300 citations

Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase.

1990 • 293 citations

Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity

1988 • 278 citations

Experimental Measurement of Aromatic Stacking Affinities in the Context of Duplex DNA

1996 • 253 citations

Hydrophobic, Non-Hydrogen-Bonding Bases and Base Pairs in DNA

1995 • 253 citations

Molecular structure of the G.A base pair in DNA and its implications for the mechanism of transversion mutations.

1986 • 216 citations

Nucleotide insertion kinetics opposite abasic lesions in DNA.

1987 • 209 citations

³¹P nuclear magnetic resonance spectra of the thiophosphate analogs of adenine nucleotides; effects of pH and Mg²⁺ binding

1978 • 189 citations

Aromatic Nonpolar Nucleosides as Hydrophobic Isosteres of Pyrimidines and Purine Nucleosides

1994 • 169 citations

Simple synthesis of 5-vinyl- and5-ethynyl-2′-deoxyuridine-5′-triphosphates

1988 • 135 citations

Synthesis and biophysical studies of short oligodeoxynudeotides with novel modifications: a possible approach to the problem of mixed base oligodeoxynudeotide synthesis

1984 • 120 citations

Enthalpy-Entropy Compensation in DNA Melting Thermodynamics

1995 • 108 citations

A universal nucleoside for use at ambiguous sites in DNA primers

1994 • 103 citations

Molecular mechanisms of manganese mutagenesis.

1984 • 96 citations

Reactions at the polymerase active site that contribute to the fidelity of Escherichia coli DNA polymerase I (Klenow fragment).

1992 • 73 citations

Kinetics of extension of O6-methylguanine paired with cytosine or thymine in defined oligonucleotide sequences

1991 • 70 citations

Kinetic analysis of Escherichia coli deoxyribonucleic acid polymerase I.

1975 • 66 citations

O4-Methyl, -ethyl, or -isopropyl substituents on thymidine in poly(dA-dT) all lead to transitions upon replication.

1986 • 66 citations

Quantum mechanical study of bases interactions in various associates in atomic dipole approximation

1976 • 65 citations

Pyrimidine · pyrimidine base-pair mismatches in DNA

1988 • 59 citations

A novel synthesis of nucleoside 5′-triphosphates

1991 • 38 citations

Mechanisms of error discrimination by Escherichia coli DNA polymerase I

1988 • 32 citations

Comparison of polymerase insertion and extension kinetics of a series of O2-alkyldeoxythymidine triphosphates and O4-methyldeoxythymidine triphosphate

1989 • 25 citations

Hydrophobic, Non-Hydrogen-Bonding Bases and Base Pairs in DNA J. Am. Chem. Soc. 1995, 117, 1863−1872

1996 • 5 citations