Mechanisms of error discrimination by Escherichia coli DNA polymerase I

Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity

1974 • 1,532 citations

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

1985 • 855 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1972 • 594 citations

Fidelity of DNA Synthesis

1982 • 516 citations

Ion-exchange chromatography of nucleotides on poly-(ethyleneimine)-cellulose thin layers

1964 • 433 citations

A new mammalian DNA polymerase with 3' to 5' exonuclease activity: DNA polymerase δ

1976 • 258 citations

Elementary steps in the DNA polymerase I reaction pathway

1983 • 179 citations

On the fidelity of DNA replication. Effect of divalent metal ion activators and deoxyrionucleoside triphosphate pools on in vitro mutagenesis.

1979 • 151 citations

Rate-limiting steps in the DNA polymerase I reaction pathway

1985 • 133 citations

Nuclear Deoxyribonucleic Acid Polymerase

1974 • 111 citations

Molecular mechanisms of manganese mutagenesis.

1984 • 96 citations

Selective inhibition of the 3' to 5' exonuclease activity associated with DNA polymerases: a mechanism of mutagenesis

1977 • 93 citations

On the enzymatic basis for mutagenesis by manganese.

1983 • 91 citations

Mechanism of selective inhibition of 3' to 5' exonuclease activity of Escherichia coli DNA polymerase I by nucleoside 5'-monophosphates

1978 • 68 citations

Kinetic measurement of 2-aminopurine X cytosine and 2-aminopurine X thymine base pairs as a test of DNA polymerase fidelity mechanisms.

1982 • 53 citations

Kinetics of base misinsertion by DNA polymerase I of Escherichia coli

1983 • 44 citations

On the fidelity of DNA replication. Nucleoside monophosphate generation during polymerization.

1981 • 43 citations

Template–dependent variation in the relative fidelity of DNA polymerase I ofEscherichia coliin the presence of Mg²⁺versus Mn²⁺

1984 • 23 citations

Selective inhibition of the polymerase activity of DNA polymerase I. Further evidence for separate active sites for polymerase and 3' to 5' exonuclease activities

1979 • 21 citations

Nonrandom substitution of 2-aminopurine for adenine during deoxyribonucleic acid synthesis in vitro

1981 • 15 citations

Effect of base-pair stability of nearest-neighbor nucleotides on the fidelity of deoxyribonucleic acid synthesis

1984 • 14 citations