Expression of 72-kDa Gelatinase (MMP-2), Collagenase (MMP-1), and Tissue Metalloproteinase Inhibitor (TIMP) in Primary Pig Skin Fibroblast Cultures Derived from Radiation-Induced Skin Fibrosis

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

1980 • 1,991 citations

Metalloproteinases and their inhibitors in matrix remodeling

1990 • 1,627 citations

The matrix‐degrading metalloproteinases

1992 • 1,383 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis.

1991 • 794 citations

Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β

1989 • 649 citations

Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein.

1986 • 645 citations

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

1989 • 594 citations

Human 92- and 72-kilodalton type IV collagenases are elastases.

1991 • 550 citations

Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors.

1986 • 531 citations

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

1985 • 506 citations

Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts.

1987 • 467 citations

Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression

1991 • 461 citations

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP)

1991 • 454 citations

The collagen substrate specificity of human skin fibroblast collagenase.

1981 • 371 citations

A rapid and reproducible assay for collagenase using [1-14C]acetylated collagen

1979 • 350 citations

The Skin: Its Structure and Response to Ionizing Radiation

1990 • 330 citations

Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells.

1987 • 323 citations

Platelet-derived growth factor-BB and transforming growth factor beta 1 selectively modulate glycosaminoglycans, collagen, and myofibroblasts in excisional wounds.

1991 • 255 citations

Expression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophages.

1987 • 235 citations

Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase

1989 • 233 citations

8 Growth Factor-Regulated Proteases and Extracellular Matrix Remodeling during Mammalian Development

1990 • 219 citations

Long-Term Overproduction of Collagen in Radiation-Induced Fibrosis

1991 • 86 citations

Monocyte procollagenase and tissue inhibitor of metalloproteinases. Identification, characterization, and regulation of secretion.

1987 • 79 citations

Dissociation of tissue inhibitor of metalloproteinases (TIMP) from enzyme complexes yields fully active inhibitor

1989 • 76 citations

Modification of collagen and noncollagenous proteins in radiation-induced muscular fibrosis

1988 • 45 citations

Collagen synthesis and deposition in cultured fibroblasts from subcutaneous radiation-induced fibrosis. Modification as a function of cell aging

1989 • 42 citations

Radiation Histopathology

2019 • 41 citations

Alveolar Macrophage/Peripheral Blood Monocyte-Derived Factors Modulate Proliferation of Primary Lines of Human Lung Fibroblasts

1987 • 36 citations

The Effect of Ionizing Radiations on Connective Tissue

1983 • 32 citations

Abnormal Proliferation and Aging of Cultured Fibroblasts From Pigs With Subcutaneous Fibrosis Induced by Gamma Irradiation

1989 • 31 citations

Muscular fibrosis induced after pig skin irradiation with single doses of¹⁹²lr γ-rays

1993 • 24 citations

Relative Radiation Sensitivity of the Integumentary System: Dose Response of the Epidermal, Microvascular, and Dermal Populations

1987 • 24 citations

Accumulation of Glycosaminoglycans in Radiation-induced Muscular Fibrosis

1992 • 21 citations

Chemoattractants in Fibrotic Disorders

1985 • 21 citations

[Late effects of radiation on normal tissues].

1994 • 17 citations

Vascular damage after acute local irradiation: a light and electron microscope study.

1986 • 16 citations

Biophysical methods for assessing the radiation dose causing lesions in the skin and subcutaneous tissues.

1986 • 15 citations

[Gamma irradiation and delayed effects: muscular fibrosis].

1990 • 14 citations

Dosimetry Study of an Accidental Overexposure to 192Ir Gamma Rays

1992 • 10 citations

Fibronectin and Glycosaminoglycan Synthesis by Fibrotic Pig Fibroblasts in Primary Culture

1989 • 8 citations

Supernatant from an Activated Human CD4+ T-Cell Clone Modulates the Proliferation and Collagen Synthesis of Human Dental Pulp Fibroblast

1987 • 7 citations