Relative Radiation Sensitivity of the Integumentary System: Dose Response of the Epidermal, Microvascular, and Dermal Populations

Radiobiology for the Radiologist.

1974 • 3,582 citations

Dose fractionation, dose rate and iso-effect relationships for normal tissue responses

1982 • 1,081 citations

Clinical Radiation Pathology

1968 • 930 citations

Changes in early and late radiation responses with altered dose fractionation: Implications for dose-survival relationships

1982 • 843 citations

Radiation Biology in Cancer Research

1980 • 782 citations

The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour

1968 • 764 citations

Radiation Response of Mammalian Cells Grown in Culture I. Repair of X-Ray Damage in Surviving Chinese Hamster Cells

2012 • 728 citations

Swine in biomedical research

1986 • 673 citations

The Effect of Multiple Small Doses of X Rays on Skin Reactions in the Mouse and a Basic Interpretation

1976 • 596 citations

Radiation Response of Mammalian Cells Grown in Culture: I. Repair of X-Ray Damage in Surviving Chinese Hamster Cells

1960 • 542 citations

Biochemistry and physiology of the skin

1983 • 487 citations

Accelerated fractionation vs hyperfractionation: Rationales for several treatments per day

1983 • 418 citations

Biochemistry and physiology of the skin

1991 • 388 citations

Swine in Biomedical Research

1966 • 353 citations

A new isoeffect curve for change in dose per fraction

1983 • 347 citations

Radiation biology in cancer research

1978 • 340 citations

The Skin of the Domestic Pig**From the University of Oregon Medical School, Portland, Oregon, and the Oregon Regional Primate Research Center, Beaverton, Oregon.

1964 • 304 citations

The influence of the number of fractions and of overall treatment time on local control and late complication rate in squamous cell carcinoma of the larynx

1983 • 289 citations

Pathology of radiation injury

1982 • 275 citations

Radiobiology for the Radiologist

1979 • 275 citations

Cumulative radiation effect part I: Fractionated treatment regimes

1971 • 273 citations

Autoradiographic Analysis of Turnover Times of Normal and Psoriatic Epidermis**From the Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Public Health Service, U.S. Department of Health, Education and Welfare.

1965 • 268 citations

Changes in the rate of repopulation during multifraction irradiation of mouse skin

1973 • 247 citations

Endothelial cell proliferation as a novel approach to targeting tumour therapy

1982 • 245 citations

The Dose-survival Relationship for Irradiation of Epithelial Cells of Mouse Skin

1967 • 220 citations

The proliferation of capillary endothelial cells.

1972 • 174 citations

Radiation-Induced Vascular Injury and Its Relation to Late Effects in Normal Tissues

1981 • 170 citations

The Treatment of Malignant Disease by Radiotherapy

1964 • 170 citations

Radiosensitivity of capillary endothelium

1973 • 164 citations

Progress in Radio-Oncology

1984 • 163 citations

The Effect of Divided Doses of 15 MeV Electrons on the Skin Response of Mice

1965 • 147 citations

Recovery and Repopulation in Vivo by Mouse Skin Epithelial Cells during Fractionated Irradiation

1967 • 144 citations

The influence of fraction size in radiotherapy on the late normal tissue reaction—II: Comparison of the effects of daily and twice-a-week fractionation on human skin

1984 • 140 citations

Experiments with Fractionated X-ray Treatment of the Skin of Pigs. I—Fractionation up to 28 Days

1963 • 138 citations

The Treatment of Malignant Disease by Radiotherapy

1964 • 131 citations

Cellular recovery in human skin reactions: Application to dose fraction number overall time relationship in radiotherapy

1973 • 127 citations

PRINCIPLES OF X RAY THERAPY OF MALIGNANT DISEASES

1934 • 125 citations

Effects of radiation on normal tissues: Hypothetical mechanisms and limitations of in situ assays of clonogenicity

1981 • 123 citations

II. Dose-time Relationships in Radiotherapy and the Validity of Cell Survival Curve Models

1963 • 119 citations

Epidermal Cell Production Rates

1975 • 117 citations

Survival of Mouse Skin Epithelial Cells Following Single and Divided Doses of X-Rays

1970 • 115 citations

Radiosensitivity of Vascular Tissue: I. Differential Radiosensitivity of Capillaries: A Quantitative in Vivo Study

1984 • 115 citations

The influence of fraction size in radiotherapy on the late normal tissue reaction—I: Comparison of the effects of daily and once-a-week fractionation on human skin

1984 • 105 citations

The Current Status of the Pigment Spread Problem

1964 • 101 citations

Progress in Radiation Therapy

1959 • 92 citations

Hyperfractionation

1982 • 87 citations

The relationship of acute to late skin injury in 2 and 5 fraction/week γ-ray therapy

1978 • 85 citations

Radiobiology of the Skin: Review of Some Effects on Epidermis and Hair

1981 • 79 citations

Two regimes with the same TDF but differing morbidity used in the treatment of stage III carcinoma of the cervix

1978 • 78 citations

Autoradiographic Studies of Turnover Time and Protein Synthesis in Pig Epidermis**From the Dermatology Branch, National Cancer Institute, Bethesda 14, Maryland. National Institutes of Health, Public Health Service, U.S. Department of Health, Education and Welfare.

1965 • 78 citations

PROLIFERATION STUDIES OF THE ENDOTHELIAL AND SMOOTH MUSCLE CELLS OF THE MOUSE MESENTERY AFTER IRRADIATION

1980 • 77 citations

Recovery and repopulation in mouse skin as a function of time after x-irradiation.

1969 • 77 citations

Ordered Structure of The Epidermis

1975 • 75 citations

Biological Effects of Neutron and Proton Irradiations

1965 • 73 citations

Skin tolerance to fractionated X-irradiation in the pig—how good a predictor is the NSD formula?

1974 • 72 citations

Test of equal effect per fraction and estimation of initial clonogen number in microcolony assays of survival after fractionated irradiation

1980 • 72 citations

Excess late subcutaneous fibrosis after irradiation of pig skin, consequent upon the application of the NSD formula

1974 • 71 citations

Biological bases for high rbe values for late effects of neutron irradiation

1982 • 71 citations

The influence of the overall treatment time in radiotherapy on the acute reaction: Comparison of the effects of daily and twice-a-week fractionation on human skin

1984 • 70 citations

Response of swine skin microvasculature to acute single exposures of X rays: quantification of endothelial changes.

1984 • 68 citations

Recovery and Repopulation in Mouse Skin after Irradiation with Cyclotron Neutrons as Compared with 250-Kv X-Rays or 15-Mev Electrons

1966 • 68 citations

Microscopic anatomy of the integument of adult swine.

1966 • 68 citations

Radiotherapy in Burkitt's lymphoma conventional or superfractionated regime—early results

1977 • 67 citations

Multiple daily fractionation in radiotherapy: Biological rationale and preliminary clinical experiences

1979 • 62 citations

Radiosensitivity of Vascular Tissue: II. Differential Radiosensitivity of Aortic Cells in Vitro

1984 • 61 citations

Experiments with Fractionated X-irradiation of the Skin of Pigs II. – Fractionation up to Five Days

1965 • 60 citations

Response of Swine Skin Microvasculature to Acute Single Exposures of X Rays: Quantification of Endothelial Changes

1984 • 60 citations

Recovery and Repopulation in Mouse Skin as a Function of Time after X-Irradiation

1969 • 60 citations

The Biological Basis of Radiation Therapy

1967 • 59 citations

The Response of Mesenteric Blood Vessels to Irradiation

1979 • 58 citations

Cell Population Kinetics following Different Regimes of Irradiation

1962 • 57 citations

Response of Swine Skin to Acute Single Exposures of X Rays: Quantification of the Epidermal Cell Changes

1979 • 55 citations

Cytotoxic insult to tissue: Effects on cell lineages

1983 • 54 citations

Autoradiographic analysis of cell kinetics in human normal epidermis and basal cell carcinoma.

1973 • 54 citations

VII. Experiments on the Skin of Pigs with Fast Neutrons and 8 MV X Rays, including some Effects of Dose Fractionation

1963 • 53 citations

Implications of the quadratic cell survival curve and human skin radiation “tolerance doses” on fractionation and superfractionation dose selection

1982 • 52 citations

The Pattern of Cellular Organization of Human Epidermis

1981 • 45 citations

TURNOVER OF CELL‐RENEWING POPULATIONS UNDERGOING CIRCADIAN RHYTHMS IN CELL PROLIFERATION

1974 • 45 citations

Radiation and the skin

1968 • 45 citations

Cell Kinetics of Epidermal Repopulation and Persistent Hyperplasia in Locally β-Irradiated Guinea Pig Skin

1972 • 44 citations

Cell Population Kinetics in Human Epidermis: In Vitro Autoradiographic Study by Double-Labeling Method

1971 • 42 citations

Cytotoxic insult to tissue : effects on cell lineages

1983 • 42 citations

THE BIOLOGICAL BASIS OF RADIATION THERAPY

1967 • 41 citations

Quantification of Morphologic, Cytologic, and Kinetic Parameters of Unirradiated Swine Skin: A Histologic Model

1984 • 41 citations

Blood flow clearance changes in pig skin after single doses of X rays

1979 • 39 citations

Skin Reactions After Different Fractionation Schedules Giving the Same Cumulative Radiation Effect

1975 • 38 citations

The Response of the Skin of Swine to Increasing Single Exposures of 250-KVp X-Rays

1968 • 36 citations

Relative biological effectiveness (RBE) of 50 MV (Be) neutrons for acute and late skin injury

1978 • 36 citations

Late Consequences of Early Skin Reactions

1970 • 35 citations

Skin and subcutaneous reactions induced by supervoltage irradiation.

1961 • 35 citations

The evaluation of an isotope clearance technique in the dermis of pig skin: A correlation of functional and morphological parameters

1980 • 33 citations

Biophysical Models in Radiation Oncology

1983 • 32 citations

Biochemical Changes in Beta-Irradiated Epidermis of Guinea Pigs

1959 • 31 citations

THE THERAPEUTIC ACTION OF IRON

1936 • 30 citations

Dose-Time Relationships for Skin Reactions and Structural Damage in Rat Feet Exposed to 250-kVp X Rays

1975 • 30 citations

The effect of ionizing radiations on capillary sprouting and vascular remodelling in the regenerating repair blastema observed in the rabbit ear chamber.

1959 • 30 citations

Evaluation of Rapid Radiation Treatment Schedules Utilizing Two Treatment Sessions per Day

1975 • 29 citations

Control of Dose Administered Once a Week and Three Times a Day According to Schedules Calculated by the CRE Formula, Using Skin Reaction as a Biological Parameter

1976 • 29 citations

The Skin

1965 • 26 citations

Skin Reaction as A Biologic Parameter for Control of Different Dose Schedules and Gap Correction

1976 • 26 citations

Biophysical Models In Radiation Oncology

1982 • 26 citations

The Response of the Skin of Swine to Increasing Multiple Exposures of X-Ray (250 kVp)

1969 • 26 citations

Response of Mouse Epidermal Cells to Single and Divided Doses of Fast Neutrons

1971 • 25 citations

The Effect of Increasing Exposures of the¹⁰B(n,α)⁷Li Reaction on the Skin of Man

1970 • 25 citations

Radiobiology of pions at TRIUMF

1982 • 24 citations

Derivation of Survival Kinetic Parameters for Cell Populations by Computer Simulation of Radiobiological Data

1977 • 24 citations

The Response of the Skin of Swine to Increasing Absorbed Doses of Radiation from a Thermal Neutron Beam, a Degraded Fission Neutron Beam, and the 10 B(n,α) 7 Li Reaction

1971 • 24 citations

Pig Epidermis: A Cell Kinetic Study

1985 • 22 citations

Quantitative and Qualitative Evaluation of Skin Erythema

1960 • 22 citations

The response of pig skin to single and fractionated high dose-rate and continuous low dose-rate 137Cs-irradiation—III

1979 • 21 citations

Quantitative and Qualitative Evaluation of Skin Erythema

1960 • 19 citations

50-MeVd→Be neutrons: A comparison of normal tissue tolerance in animals with clinical observations in patients

1982 • 19 citations

Radiation-induced Damage to Blood Vessels: A Study of Dose–effect Relationship with Time after X-irradiation

1978 • 19 citations

Review of parameters characterising response of normal connective tissue to radiation

1976 • 18 citations

The relative biological effectiveness of fast neutrons (42MeVd→Be) for early and late normal tissue injury in the pig

1982 • 16 citations

Mitotic and Labelling Activity In Normal Human Epidermis In Vivo

1984 • 15 citations

The Relation of Tissue Recovery and the Healing Process to the Periodicity of Radiation Effects

1939 • 15 citations

Reduced Growth Rates of Hair in Mice Following Radiation

1966 • 15 citations

V. Some Comparisons of Fractionation Effects by Erythema Measurements on Human Skin

1963 • 15 citations

Cytokinetics of Regeneration in β-Irradiated Guinea-Pig Epidermis

1977 • 14 citations

Early Vascular Injury in the Irradiated Chick Embryo: Effect of Exposure Time

1969 • 14 citations

Mechanisms of Acute Injury in the γ-Irradiated Chicken In Vivo Studies of Dose Protraction Effects on the Microvasculature

1971 • 11 citations

Lack of correlation between basal cell survival and gross response in irradiated swine skin

1984 • 11 citations

Repair of sublethal radiation damage by capillaries

1979 • 11 citations

Cell Population Kinetics in Radiation-induced Hyperplastic Epidermis of Guinea-pig Skin

1969 • 10 citations

Tritiated Thymidine Uptake in Pig Skin

1975 • 10 citations

Pion radiotherapy at LAMPF

1982 • 9 citations

Pions, Vancouver

1982 • 9 citations

Comparison of the Observed Results of Irradiation on the Skin with Those Expected from an Idealized Model

1969 • 8 citations

Dose-time relationship: Computation of cell lethality following fractionated radiation therapy

1978 • 8 citations

ISO-effect tables and therapeutic ratios for epidermoid cancer and normal tissue stroma

1983 • 7 citations

Experimental condition and the acute reaction of mouse skin to ionizing radiation.

1983 • 7 citations

Radiobiology of pions at LAMPF

1982 • 6 citations

The role of radiation in the treatment of cancer: Radiobiologic and cell kinetic concepts

1984 • 6 citations

“Battered data”—Some clinical effects of the abuse of multiple regression methods: The NSD

1981 • 4 citations

Acute normal tissue tolerance to 7 day per week accelerated fractionation

1984 • 4 citations

Experimental Condition and the Acute Reaction of Mouse Skin to Ionizing Radiation

1983 • 4 citations

Book reviewSymposium on the rehabilitation of the Cancer Disabled. Edited by RavenR. W., pp. vi + 123, 1972. (London, Heinemann), £2·50.

1973 • 2 citations

Cumulative radiation dose records

1969 • 1 citations

Quantitative and Qualitative Evaluation of Skin Erythema

1966 • 1 citations