Transepithelial transport and cellular accumulation of steroid hormones and polychlorobiphenyl in porcine kidney cells expressed with human P-glycoprotein

THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

1989 • 2,060 citations

Expression of a multidrug-resistance gene in human tumors and tissues.

1987 • 1,547 citations

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.

1987 • 1,080 citations

Polychlorinated Biphenyls (PCBs) and Polybrominated Biphenyls (PBBs): Biochemistry, Toxicology, and Mechanism of Action

1984 • 793 citations

The multidrug transporter, a double-edged sword.

1988 • 763 citations

Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone.

1992 • 677 citations

Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies.

1986 • 561 citations

Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).

1992 • 335 citations

A Dose–Response Analysis of the Reproductive Effects of a Single Gestational Dose of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Male Long Evans Hooded Rat Offspring

1997 • 217 citations

Reproductive Toxicity and Tissue Concentrations of Low Doses of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Male Offspring Rats Exposed Throughout Pregnancy and Lactation

1998 • 176 citations

Evidence for PCBs as neurodevelopmental toxicants in humans.

1997 • 169 citations

Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein.

1990 • 143 citations

Feeding great lakes fish to mink: Effects on mink and accumulation and elimination of PCBS by mink

1983 • 124 citations

Subchronic effects of 2,3,7,8-TCDD or PCBs on thyroid hormone metabolism: use in risk assessment

1995 • 118 citations

Effects of Maternal Exposure to Polychlorobiphenyls (PCBs) on F1 Generation Behavior in the Rat

1988 • 111 citations

Potency of various polycyclic aromatic hydrocarbons as inducers of CYP1A1 in rat hepatocyte cultures

1999 • 102 citations

Effects of Polychlorinated Biphenyls (PCBs) and Dioxins on Growth and Development

1994 • 95 citations

P‐glycoprotein‐mediated transcellular transport of MDR‐reversing agents

1993 • 92 citations

Transcriptional suppression of estrogen receptor gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

1998 • 85 citations

Estrogen and aryl hydrocarbon receptor expression and crosstalk in human Ishikawa endometrial cancer cells

2000 • 84 citations

Alteration of Substrate Specificity by Mutations at the His⁶¹ Position in Predicted Transmembrane Domain 1 of Human MDR1/P-Glycoprotein

1997 • 52 citations

TRIBUTYLTIN MODULATES 3,3',4,4',5-PENTACHLOROBIPHENYL (PCB-126)-INDUCED HEPATIC CYP1A ACTIVITY IN CHANNEL CATFISH, ICTALURUS PUNCTATUS

1998 • 37 citations

Affinities for the aryl hydrocarbon receptor, potencies as aryl hydrocarbon hydroxylase inducers and relative toxicities of polychlorinated biphenyls. A congener specific approach

1993 • 36 citations

Relationship between expression level of p-glycoprotein and daunorubicin transport in LLC-PK1 cells transfected with human MDR1 gene

1997 • 28 citations