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The language of covalent histone modifications

2000 • 8,260 citations

The Regulation of Immunity to Leishmania Major

1995 • 1,265 citations

Histone and chromatin cross-talk

2003 • 1,187 citations

Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

2000 • 793 citations

Modulation of Chromatin Structure Regulates Cytokine Gene Expression during T Cell Differentiation

1998 • 697 citations

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells.

1983 • 654 citations

The Nucleosome

2004 • 636 citations

TH cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

2002 • 517 citations

Early Transcription and Silencing of Cytokine Genes Underlie Polarization of T Helper Cell Subsets

2001 • 498 citations

The Importance of Th2 Cytokines in Protective Immunity to Nematodes

1992 • 352 citations

Th2 Lineage Commitment and Efficient IL-4 Production Involves Extended Demethylation of the IL-4 Gene

2002 • 328 citations

Cutting Edge: Changes in Histone Acetylation at the IL-4 and IFN-γ Loci Accompany Th1/Th2 Differentiation

2002 • 326 citations

Cell-Type-Restricted Binding of the Transcription Factor NFAT to a Distal IL-4 Enhancer In Vivo

2000 • 270 citations

Regulation of the Th2 Cytokine Locus by a Locus Control Region

2003 • 222 citations

Deletion of a coordinate regulator of type 2 cytokine expression in mice

2001 • 196 citations

Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4

2003 • 186 citations

Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells

2003 • 145 citations

The relationship between immune interferon production and proliferation in antigen-specific, MHC-restricted T cell lines and clones.

1983 • 141 citations

Coordinate Regulation of the IL-4, IL-13, and IL-5 Cytokine Cluster in Th2 Clones Revealed by Allelic Expression Patterns

2000 • 139 citations

Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region.

1998 • 139 citations

A 3′ Enhancer in the IL-4 Gene Regulates Cytokine Production by Th2 Cells and Mast Cells

2002 • 117 citations

An Intron Transcriptional Enhancer Element Regulates IL-4 Gene Locus Accessibility in Mast Cells

2000 • 72 citations

IL-4-Induced GATA-3 Expression Is a Time-Restricted Instruction Switch for Th2 Cell Differentiation

2004 • 60 citations

Basal Chromatin Modification at the IL-4 Gene in Helper T Cells

2003 • 36 citations