Intracellular protein phosphorylation in murine peritoneal macrophages in response to bacterial lipopolysaccharide (LPS): Effects of kinase-inhibitors and LPS-induced tolerance

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Secretory products of macrophages.

1987 • 2,670 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Calmodulin Plays a Pivotal Role in Cellular Regulation

1980 • 2,441 citations

Phosphorylation-Dephosphorylation of Enzymes

1979 • 2,205 citations

The role of protein phosphorylation in neural and hormonal control of cellular activity

1982 • 1,116 citations

A thousand and one protein kinases

1987 • 1,066 citations

Bacterial Endotoxins and Host Immune Responses

1980 • 629 citations

Recognition and plasma clearance of endotoxin by scavenger receptors

1991 • 529 citations

Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide.

1986 • 415 citations

Bacterial Endotoxins

1992 • 372 citations

B lymphocyte receptors and polyphosphoinositide degradation

1985 • 332 citations

Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages.

1991 • 318 citations

The Expansion Rate and Size of the Universe

1992 • 248 citations

THE FATE OF BACTERIA WITHIN PHAGOCYTIC CELLS

1963 • 181 citations

Differential inhibition of IL-1 and TNF-alpha mRNA expression by agents which block second messenger pathways in murine macrophages.

1988 • 152 citations

Translocation of protein kinase C during membrane immunoglobulin-mediated transmembrane signaling in B lymphocytes.

1986 • 136 citations

Molecular mechanisms in tumor-cell killing by activated macrophages

1983 • 127 citations

Molecular cloning and characterization of plastin, a human leukocyte protein expressed in transformed human fibroblasts.

1988 • 124 citations

Lipid A binding sites in membranes of macrophage tumor cells.

1988 • 112 citations

Beneficial effects of endotoxins

1984 • 98 citations

LPS induces altered phosphate labeling of proteins in murine peritoneal macrophages.

1986 • 88 citations

Transcriptional and post-transcriptional mechanisms involved in the differential expression of LPS-induced IL-1 and TNF mRNA.

1991 • 73 citations

Increased phosphatidylinositol metabolism is an important but not an obligatory early event in B lymphocyte activation.

1985 • 67 citations

On the role of protein kinases in regulating neutrophil actin association with the cytoskeleton.

1991 • 62 citations

Induction of Endotoxin Tolerance

1983 • 60 citations

Lipopolysaccharide-mediated macrophage activation: the role of calcium in the generation of tumoricidal activity.

1987 • 55 citations

Interactions of bacterial lipopolysaccharide with microtubule proteins.

1992 • 49 citations

Purification and characterization of the 65-kDa protein phosphorylated in murine macrophages by stimulation with bacterial lipopolysaccharide.

1991 • 49 citations

Secretion of IL-1: role of protein kinase C.

1992 • 47 citations

The mechanism of macrophage activation induced by Ca2+ ionophore

1983 • 44 citations

Calcium ionophore A23187 does not stimulate lipopolysaccharide nonresponsive C3H/HeJ peritoneal macrophages to produce interleukin 1.

1987 • 36 citations

Detection of lipopolysaccharide-binding proteins on membranes of murine lymphocyte and macrophage-like cell lines

1991 • 32 citations

65-Kilodalton protein phosphorylated by interleukin 2 stimulation bears two putative actin-binding sites and two calcium-binding sites

1990 • 30 citations

Studies on the center of activity of endotoxin (lipid A). From the viewpoint of correlation of chemical structure and biological activity.

1989 • 21 citations

Non-histone chromatin proteins of B lymphocytes stimulated by lipopolysaccharide

1978 • 19 citations

Binding of calmodulin to the microfilament network correlates with induction of a macrophage tumoricidal response.

1985 • 18 citations

Non-histone chromatin proteins of B lymphocytes stimulated by lipopolysaccharide

1978 • 15 citations