Neuroprotective actions of GR89696, a highly potent and selective κ‐opioid receptor agonist

Delayed neuronal death in the gerbil hippocampus following ischemia

1982 • 2,856 citations

U-50,488: a selective and structurally novel non-Mu (kappa) opioid agonist.

1983 • 795 citations

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil

1987 • 647 citations

MK-801 reduced cerebral ischemic injury by inducing hypothermia

1990 • 205 citations

CI‐977, a novel and selective agonist for the κ‐opioid receptor

1990 • 150 citations

Effect of Lactacidosis on Pyridine Nucleotide Stability During Ischemia in Mouse Brain

1987 • 140 citations

ISCHAEMIC BRAIN DAMAGE: THE ROLE OF EXCITATORY ACTIVITY AND OF CALCIUM ENTRY

1985 • 115 citations

Differential sensitivity of models of antinociception in the rat, mouse and guinea‐pig to μ‐and κ‐opioid receptor agonists

1987 • 101 citations

Pharmacological profile of PD 117302, a selective κ‐opioid agonist

1987 • 91 citations

Protection from cerebral ischemia by U-50,488E, a specific kappa opioid analgesic agent

1985 • 88 citations

Beneficial effects of the κ opioid receptor agonist U-50488H in experimental acute brain and spinal cord injury

1987 • 79 citations

Diuretic actions in man of a selective kappa opioid agonist: U-62,066E.

1987 • 74 citations

U-54494A: a unique anticonvulsant related to kappa opioid agonists.

1987 • 71 citations

A novel series of potent and selective agonists at the opioid κ-receptor

1988 • 69 citations

Quantitative analysis of effects of kappa-opioid agonists on postischemic hippocampal CA1 neuronal necrosis in gerbils.

1988 • 66 citations

Protection from ischemia-induced cerebral edema in the rat by U-50488H, a kappa opioid receptor agonist

1987 • 64 citations

A series of novel, highly potent and selective agonists for the κ‐opioid receptor

1990 • 41 citations

The anticonvulsant action of CI-977, a selective κ-opioid receptor agonist: a possible involvement of the glycine/NMDA receptor complex

1990 • 34 citations

In vivo evidence for spinal delta-opiate receptor-operated antinociception

1986 • 33 citations

Treatment of stroke with opiate antagonists — Effects of exogenous antagonists and dynorphin 1–13

1985 • 33 citations

PD117302, a selective non-peptide opioid kappa agonist, protects against NMDA and maximal electroshock convulsions in rats

1990 • 33 citations

Evidence that endogenous enkephalins and a δ opioid receptor agonist have a common site of action in spinal antinociception

1988 • 27 citations

Effect of iopanoic acid on basal and thyrotropin-stimulated thyroid hormone levels in suckling rat pups

1990 • 14 citations

Pd 117302 attenuates glutamate neurotoxicity in vitro

1990 • 3 citations