PD117302, a selective non-peptide opioid kappa agonist, protects against NMDA and maximal electroshock convulsions in rats

Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays.

1988 • 399 citations

Classification of Opioids on the Basis of Change in Seizure Threshold in Rats

1979 • 152 citations

Pharmacological profile of PD 117302, a selective κ‐opioid agonist

1987 • 91 citations

U50,488, a highly selective kappa opioid: anticonvulsant profile in rats.

1986 • 82 citations

PD117302: a selective agonist for the κ‐opioid receptor

1988 • 76 citations

U-54494A: a unique anticonvulsant related to kappa opioid agonists.

1987 • 71 citations

Evidence for mu opioid receptor mediation of enkephalin-induced electroencephalographic seizures.

1987 • 62 citations

Modification of kindled amygdaloid seizures by opiate agonists and antagonists.

1984 • 58 citations

Selective kappa antagonist properties of nor-binaltorphimine in the rat mes seizure model

1989 • 51 citations

The anticonvulsant effect of opioids and opioid peptides against maximal electroshock seizures in rats

1984 • 43 citations

Intranigral dynorphin-1-13 suppresses kindled seizures by a naloxone-insensitive mechanism

1987 • 30 citations

An in vitro profile of activity for the (+) and (−) enantiomers of spiradoline and PD117302

1989 • 30 citations