A series of novel, highly potent and selective agonists for the κ‐opioid receptor

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

Statistical Method in Biological Assay.

1979 • 3,679 citations

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

1976 • 2,883 citations

Endogenous opioid peptides: multiple agonists and receptors

1977 • 2,494 citations

U-50,488: a selective and structurally novel non-Mu (kappa) opioid agonist.

1983 • 795 citations

[3H]U-69593 a highly selective ligand for the opioid κ receptor

1985 • 439 citations

Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse.

1984 • 417 citations

A kappa opioid effect: increased urination in the rat.

1983 • 224 citations

Rabbit vas deferens: A specific bioassay for opioid κ-receptor agonists

1981 • 180 citations

Differential sensitivity of models of antinociception in the rat, mouse and guinea‐pig to μ‐and κ‐opioid receptor agonists

1987 • 101 citations

Pharmacological profile of PD 117302, a selective κ‐opioid agonist

1987 • 91 citations

Norbinaltorphimine: Antagonist profile at κ opioid receptors

1987 • 88 citations

Determination of receptors that mediate opiate side effects in the mouse

1983 • 80 citations

Effect of the Opioid Kappa-Receptor Agonist U50488H on the Secretion of Arginine Vasopressin

1988 • 77 citations

Diuretic actions in man of a selective kappa opioid agonist: U-62,066E.

1987 • 74 citations

A novel series of potent and selective agonists at the opioid κ-receptor

1988 • 69 citations

The opioid receptors in the hamster vas deferens are of the δ-type

1985 • 49 citations

Determination of the receptor selectivity of opioid agonists in the guinea‐pig ileum and mouse vas deferens by use of β‐funaltrexamine

1985 • 48 citations

In-vivo studies on kappa opioid receptors

1986 • 40 citations

Effects of the highly selective kappa opioid, U-50, 488, on renal function in the anesthetized dog.

1984 • 36 citations

Profile of activity of κ receptor agonists in the rabbit vas deferens

1985 • 35 citations

Effect of β-funaltrexamine on opioid side-effects produced by morphine and U-50, 488H

1985 • 32 citations

The opioid κ-selective compound U−50,488H does not inhibit intestinal propulsion in rats

1984 • 31 citations

Pharmacology of δ-opioid receptor in the hamster vas deferens

1986 • 25 citations

Lack of evidence for ε-opioid receptors in the rat vas deferens

1988 • 18 citations

Evaluation of the receptor selectivities of opioid drugs by investigating the block of their effect on urine output by beta-funaltrexamine.

1987 • 16 citations

Characterisation of the δ-opioid receptor on the hamster vas deferens

1985 • 9 citations

Effects of full and partial. Kappa agonists and mu agonists on urine output of normally hydrated rats

1984 • 9 citations

Delta receptors in the rat vas deferens.

1986 • 6 citations