Desmosomes and hemidesmosomes

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

1991 • 1,014 citations

Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes

1991 • 771 citations

Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments.

1991 • 755 citations

A Homolog of the armadillo Protein in Drosophila (Plakoglobin) Associated with E-Cadherin

1991 • 632 citations

Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.

1991 • 574 citations

Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes.

1990 • 486 citations

Morphoregulatory molecules

1988 • 460 citations

The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties.

1992 • 385 citations

Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless

1990 • 374 citations

The anchoring filament protein kalinin is synthesized and secreted as a high molecular weight precursor.

1992 • 345 citations

Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic.

1992 • 337 citations

Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules.

1990 • 327 citations

Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4.

1990 • 323 citations

The integrin alpha 6 beta 4 is a laminin receptor.

1992 • 299 citations

Demonstration of an Adhering-Junction Molecule (Plakoglobin) in the Autoantigens of Pemphigus Foliaceus and Pemphigus Vulgaris

1989 • 280 citations

Plakoglobin, or an 83-kD homologue distinct from beta-catenin, interacts with E-cadherin and N-cadherin.

1992 • 280 citations

Cloning and sequence analysis of beta-4 cDNA: an integrin subunit that contains a unique 118 kd cytoplasmic domain.

1990 • 278 citations

The dermal-epidermal junction of human skin contains a novel laminin variant.

1992 • 268 citations

Amino acid sequence of a novel integrin beta 4 subunit and primary expression of the mRNA in epithelial cells.

1990 • 249 citations

Identification of a new hemidesmosomal protein, HD1: a major, high molecular mass component of isolated hemidesmosomes.

1992 • 231 citations

A function for the integrin alpha 6 beta 4 in the hemidesmosome.

1991 • 225 citations

Human bullous pemphigoid antigen (BPAG1). Amino acid sequences deduced from cloned cDNAs predict biologically important peptide segments and protein domains.

1991 • 222 citations

Structure and interactions of desmosomal and other cadherins

1992 • 201 citations

Human autoantibodies against desmoplakins in paraneoplastic pemphigus.

1992 • 198 citations

Pemphigus and pemphigoid as paradigms of organ-specific, autoantibody-mediated diseases.

1989 • 196 citations

The desmoplakin carboxyl terminus coaligns with and specifically disrupts intermediate filament networks when expressed in cultured cells.

1992 • 194 citations

Cloning and sequencing of rat plectin indicates a 466-kD polypeptide chain with a three-domain structure based on a central alpha-helical coiled coil.

1991 • 188 citations

Cloning and sequence analysis of desmosomal glycoproteins 2 and 3 (desmocollins): cadherin-like desmosomal adhesion molecules with heterogeneous cytoplasmic domains.

1991 • 188 citations

Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules.

1991 • 185 citations

Molecular cloning of the human α6 integrin subunit

1991 • 183 citations

Comparative structural analysis of desmoplakin, bullous pemphigoid antigen and plectin: members of a new gene family involved in organization of intermediate filaments

1992 • 169 citations

Comparison of molecularly cloned bullous pemphigoid antigen to desmoplakin I confirms that they define a new family of cell adhesion junction plaque proteins

1991 • 162 citations

Stratification-related expression of isoforms of the desmosomal cadherins in human epidermis

1993 • 159 citations

Cytoplasmic Domain of the 180-kD Bullous Pemphigoid Antigen, a Hemidesmosomal Component: Molecular and Cell Biologic Characterization

1992 • 155 citations

Hemidesmosome formation in vitro.

1983 • 154 citations

Hemidesmosome Heterogeneity in Junctional Epidermolysis Bullosa Revealed by Morphometric Analysis

1986 • 144 citations

Identification of two collagen domains within the bullous pemphigoid autoantigen, BP180.

1991 • 139 citations

Identification of a basic protein of Mr 75,000 as an accessory desmosomal plaque protein in stratified and complex epithelia.

1988 • 138 citations

Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome

1991 • 131 citations

Desmosome biogenesis in the mouse preimplantation embryo

1991 • 122 citations

Desmosomal glycoproteins II and III. Cadherin-like junctional molecules generated by alternative splicing

1991 • 120 citations

Desmoglein shows extensive homology to the cadherin family of cell adhesion molecules

1990 • 120 citations

Genomic organization of collagenous domains and chromosomal assignment of human 180-kDa bullous pemphigoid antigen-2, a novel collagen of stratified squamous epithelium.

1991 • 110 citations

Desmoplakin I and desmoplakin II

1989 • 105 citations

An immunohistological study of desmosomes in Darier's disease and Hailey-Hailey disease

1991 • 104 citations

The new basement membrane antigen recognized by the monoclonal antibody GB3 is a large size glycoprotein: modulation of its expression by retinoic acid

1988 • 101 citations

Structure and hydrodynamic properties of plectin molecules

1987 • 92 citations

Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene.

1991 • 92 citations

Calcium-induced desmosome formation in cultured kidney epithelial cells

1986 • 88 citations

Bullous pemphigoid antigen (BPAG1): cDNA cloning and mapping of the gene to the short arm of human chromosome 6

1990 • 87 citations

Anchoring filaments of the amphibian epidermal-dermal junction traverse the basal lamina entirely from the plasma membrane of hemidesmosomes to the dermis

1984 • 76 citations

Regulation of desmosome assembly in MDCK epithelial cells: coordination of membrane core and cytoplasmic plaque domain assembly at the plasma membrane.

1991 • 74 citations

The molecular biology of desmosomes and hemidesmosomes: ′What's in a name?'

1992 • 73 citations

Early expression of desmosomal components during kidney tubule morphogenesis in human and murine embryos

1990 • 72 citations

A new high molecular mass protein showing unique localization in desmosomal plaque.

1989 • 72 citations

Chromosomal assignment of the human genes coding for the major proteins of the desmosome junction, desmoglein DGI (DSG), desmocollins DGIIIII (DSC), desmoplakins DPIII (DSP), and plakoglobin DPIII (JUP)

1991 • 70 citations

Detection and Partial Characterization o f A Midlamina Lucida-Hemidesmosome-Associated Antigen (19-DEJ-1) Present Within Human Skin

1989 • 53 citations

Cloning of Partial cDNA for Mouse 180-kDa Bullous Pemphigoid Antigen (BPAG2), a Highly Conserved Collagenous Protein of the Cutaneous Basement Membrane Zone

1992 • 52 citations

Accumulation of a microtubule-binding protein, pp170, at desmosomal plaques

1992 • 49 citations

Desmosome development in an in vitro model.

1980 • 48 citations

Development of desmosomal adhesion between MDCK cells following calcium switching

1990 • 48 citations

Differential Expression of Laminin Isoforms and β4 Integrin Epitopes in the Basement Membrane Zone of Normal Human Skin and Basal Cell Carcinomas

1992 • 46 citations

Transforming Growth Factor-β Stimulates the Expression of Desmosomal Proteins in Bronchial Epithelial Cells

1992 • 44 citations

The human gene (DSG2) coding for HDGC, a second member of the desmoglein subfamily of the desmosomal cadherins, is, like DSG1 coding for desmoglein DGI, assigned to chromosome 18

1992 • 40 citations

Hemidesmosomes in the epithelial cell line 804G: Their fate during wound closure, mitosis and drug induced reorganization of the cytoskeleton

1992 • 38 citations

A study of desmosomes in colorectal carcinoma

1990 • 34 citations

Immunohistochemical Staining with Monoclonal Antibody 32–2B to Desmosomal Glycoprotein 1: Its Role in the Histological Assessment of Urothelial Carcinomas

1990 • 33 citations

The human gene (DSG3) coding for the pemphigus vulgaris antigen is, like the genes coding for the other two known desmogleins, assigned to chromosome 18

1992 • 32 citations

Cell adhesion in Hailey–Hailey disease and Darier's disease: immunocytological and explant-tissue-culture studies

1991 • 32 citations

AN INSECT DESMOSOME

1970 • 30 citations

Keratinization is associated with the expression of a new protein related to the desmosomal cadherins DGII/III

1991 • 28 citations

Desmosome assembly in MDCK epithelial cells does not require the presence of functional microtubules

1992 • 25 citations

Transforming Growth Factor-β Up-Regulates the Expression of the Genes for β4 Integrin and Bullous Pemphigoid Antigens (BPAG1 and BPAG2) in Normal and Transformed Human Keratinocytes

1992 • 24 citations

Desmosomal Proteins: Mediators of Intercellular Coupling and Intermediate Filament Anchorage

1992 • 17 citations