Defective expression of the interleukin-2/interleukin-15 receptor β subunit leads to a natural killer cell–deficient form of severe combined immunodeficiency

Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice

2000 • 1,578 citations

Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans

1993 • 1,317 citations

IL-15 Receptor Maintains Lymphoid Homeostasis by Supporting Lymphocyte Homing and Proliferation

1998 • 1,293 citations

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

1995 • 1,079 citations

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1995 • 881 citations

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

1995 • 875 citations

Defective IL7R expression in T-B+NK+ severe combined immunodeficiency

1998 • 805 citations

Interleukin-2 Receptor β Chain Gene: Generation of Three Receptor Forms by Cloned Human α and β Chain cDNA's

1989 • 680 citations

Immune Responses in Interleukin-2-Deficient Mice

1993 • 476 citations

Abnormal Development of Intestinal Intraepithelial Lymphocytes and Peripheral Natural Killer Cells in Mice Lacking the IL-2 Receptor β Chain

1997 • 359 citations

Multistage Regulation of Th1-Type Immune Responses by the Transcription Factor IRF-1

1997 • 354 citations

A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors

1987 • 306 citations

The interleukin-7 receptor alpha chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis.

1996 • 213 citations

The Molecular Basis of X‐Linked Severe Combined Immunodeficiency: The Role of the Interleukin‐2 Receptor γ Chain as a Common γ Chain, γc

1994 • 180 citations

NATURALLY OCCURRING PRIMARY DEFICIENCIES OF THE IMMUNE SYSTEM

1997 • 159 citations

The Immediate-Early Gene Product Egr-1 Regulates the Human Interleukin-2 Receptor β-Chain Promoter through Noncanonical Egr and Sp1 Binding Sites

1997 • 86 citations

Receptor to nucleus signaling by prolactin and interleukin 2 via activation of latent DNA-binding factors.

1994 • 70 citations

Diagnosis of X-linked lymphoproliferative disease by analysis of SLAM-associated protein expression

2000 • 66 citations

Bruton's tyrosine kinase expression and activity in X-linked agammaglobulinaemia (XLA): the use of protein analysis as a diagnostic indicator of XLA.

1998 • 58 citations

Bruton's tyrosine kinase expression and activity in X-linked agammaglobulinaemia (XLA): the use of protein analysis as a diagnostic indicator of XLA

1998 • 43 citations

Development of Autologous, Oligoclonal, Poorly Functioning T Lymphocytes in a Patient With Autosomal Recessive Severe Combined Immunodeficiency Caused by Defects of the Jak3 Tyrosine Kinase

1998 • 38 citations

Development of Autologous T Lymphocytes in Two Males with X-Linked Severe Combined Immune Deficiency: Molecular and Cellular Characterization

2000 • 37 citations

Effects of granulocyte colony-stimulating factor (G-CSF) treatment on granulocyte function and receptor expression in patients with ventilator-dependent pneumonia

1998 • 27 citations