Self-Protective Mechanism Awakened by Glutamate in Retinal Ganglion Cells

Oxidative Stress, Glutamate, and Neurodegenerative Disorders

1993 • 3,746 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Metal ion-catalyzed oxidation of proteins: Biochemical mechanism and biological consequences

1990 • 1,143 citations

CREB: A Major Mediator of Neuronal Neurotrophin Responses

1997 • 936 citations

Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB

1994 • 732 citations

Bcl-2 Gene Family and the Regulation of Programmed Cell Death

1994 • 725 citations

Prevention of Programmed Cell Death of Sympathetic Neurons by the bcl-2 Proto-Oncogene

1992 • 724 citations

Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section

1992 • 712 citations

Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death

1992 • 668 citations

Elevated Glutamate Levels in the Vitreous Body of Humans and Monkeys With Glaucoma

1996 • 646 citations

bcl-2 inhibits death of central neural cells induced by multiple agents.

1993 • 631 citations

Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma.

2000 • 499 citations

The p75 neurotrophin receptor

1994 • 480 citations

CREB Couples Neurotrophin Signals to Survival Messages

2000 • 455 citations

Molecular basis of glutamate toxicity in retinal ganglion cells

1997 • 371 citations

Neurotrophin Signaling via Trks and p75

1999 • 356 citations

Patterns of glutamate immunoreactivity in the goldfish retina

1990 • 275 citations

Ischemic Tolerance in Murine Cortical Cell Culture: Critical Role for NMDA Receptors

1999 • 242 citations

Pharmacological strategies in CNS trauma

1992 • 230 citations

A new family of neurotransmitter transporters: the high‐affinity glutamate transporters

1993 • 228 citations

Chronology of optic nerve head and retinal responses to elevated intraocular pressure.

2000 • 225 citations

The Protooncogene bcl‐2 Inhibits Apoptosis in PC12 Cells

1993 • 222 citations

Degeneration of Spared Axons Following Partial White Matter Lesion: Implications for Optic Nerve Neuropathies

1998 • 214 citations

Brain-Derived Neurotrophic Factor and Neurotrophin-4/5 Stimulate Growth of Axonal Branches from Regenerating Retinal Ganglion Cells

1996 • 206 citations

Activity-dependent Release of Brain-derived Neurotrophic Factor Underlies the Neuroprotective Effect of N-Methyl-d-aspartate

1998 • 203 citations

Neurotrophin‐4/5 (NT‐4/5) increases adult rat retinal ganglion cell survival and neurite outgrowth in vitro

1994 • 169 citations

Elevation of Intraocular Glutamate Levels in Rats With Partial Lesion of the Optic Nerve

1998 • 168 citations

The Activation of Metabotropic Glutamate Receptors Protects Nerve Cells from Oxidative Stress

1998 • 145 citations

Glutamate, GABA, and glycine in the human retina: An immunocytochemical investigation

1991 • 144 citations

Attenuation of Excitatory Amino Acid Toxicity by Metabotropic Glutamate Receptor Agonists and Aniracetam in Primary Cultures of Cerebellar Granule Cells

1993 • 109 citations

Importance of the Bcl-2 family in cell death regulation

1996 • 107 citations

Glutamate Receptor Signaling Interplay Modulates Stress-sensitive Mitogen-activated Protein Kinases and Neuronal Cell Death

1999 • 101 citations

Neuroprotective Effects of Group III mGluR in Traumatic Neuronal Injury

1997 • 94 citations

Upregulation of the Anti-apoptotic Protein Bcl-2 May Be an Early Event in Neurodegeneration: Studies on Parkinson's and Incidental Lewy Body Disease

1997 • 89 citations

Excitatory transmitter neurotoxicity

1994 • 82 citations

T-cell-based immunity counteracts the potential toxicity of glutamate in the central nervous system

2001 • 71 citations

Activation of Multiple Metabotropic Glutamate Receptor Subtypes Prevents NMDA‐induced Excitotoxicity in Rat Hippocampal Slices

1996 • 71 citations

New mechanisms of excitatory transmitter neurotoxicity.

1994 • 64 citations

Immunocytochemical localization of excitatory and inhibitory neurotransmitters in the zebrafish retina

1999 • 63 citations

Neurotrophins and their receptors in the tench retina during optic nerve regeneration

1999 • 57 citations

Activation of NMDA receptors protects against glutamate neurotoxicity in the retina: evidence for the involvement of neurotrophins

1999 • 57 citations

Amyotrophic lateral sclerosis

1994 • 53 citations

Glutamate immunoreactivity in the cat retina: A quantitative study

1996 • 52 citations

Current understanding of neuroprotection in glaucoma

2002 • 49 citations

Excitatory mechanisms in retinal ganglion cell death in primary open angle glaucoma (POAG).

1997 • 46 citations

Increases in levels of brain-derived neurotrophic factor mRNA and its promoters after transient forebrain ischemia in the rat brain

1998 • 38 citations

The neurotrophin receptors trkA, trkB and trkC are differentially regulated after excitotoxic lesion in rat striatum

1999 • 35 citations

Neurotrophin receptors (Trk A, Trk B, and Trk C) in the developing and adult human retina

1999 • 32 citations

Excitatory amino acids and neurotoxicity.

1993 • 31 citations

Expression of p75 neurotrophin receptor in the injured and regenerating rat retina

1999 • 25 citations

BDNF gene transcripts in mesencephalic neurons and its differential regulation by NMDA

1998 • 23 citations

Chapter 16 Neurodegeneration and glutamate induced oxidative stress

1998 • 22 citations

Expression of Brain-derived Neurotrophic Factor Gene in Retina Following Vitreous Tap

1999 • 2 citations