A new family of neurotransmitter transporters: the high‐affinity glutamate transporters

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1993 • 6,762 citations

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

1983 • 2,376 citations

Analysis of membrane and surface protein sequences with the hydrophobic moment plot

1984 • 2,234 citations

Glutamate: A Neurotransmitter in Mammalian Brain

1984 • 1,981 citations

Glutamate neurotoxicity in cortical cell culture

1987 • 1,400 citations

Primary structure and functional characterization of a high-affinity glutamate transporter

1992 • 1,319 citations

Cloning and expression of a rat brain L-glutamate transporter

1992 • 1,230 citations

Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain.

1992 • 1,185 citations

Decreased Glutamate Transport by the Brain and Spinal Cord in Amyotrophic Lateral Sclerosis

1992 • 1,170 citations

A Requirement for the Intercellular Messenger Nitric Oxide in Long-Term Potentiation

1991 • 1,136 citations

Role of amino acid transport and countertransport in nutrition and metabolism.

1990 • 1,101 citations

The release and uptake of excitatory amino acids

1990 • 1,090 citations

The Time Course of Glutamate in the Synaptic Cleft

1992 • 1,071 citations

Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger.

1991 • 1,016 citations

Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter

1991 • 928 citations

Cloning and Expression of a Rat Brain GABA Transporter

1990 • 873 citations

Cloning and expression of a functional serotonin transporter from rat brain

1991 • 822 citations

The role of divalent cations in the N‐methyl‐D‐aspartate responses of mouse central neurones in culture.

1988 • 810 citations

Sequence identification of 2,375 human brain genes

1992 • 764 citations

Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake

1990 • 728 citations

Ischemia-Induced Shift of Inhibitory and Excitatory Amino Acids from Intra- to Extracellular Compartments

1985 • 663 citations

Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors

1990 • 649 citations

Mechanisms Underlying Long-Term Potentiation of Synaptic Transmission

1991 • 615 citations

Cloning of a Serotonin Transporter Affected by Antidepressants

1991 • 613 citations

Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus

1989 • 612 citations

NMDA receptors activate the arachidonic acid cascade system in striatal neurons

1988 • 600 citations

The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.

1994 • 598 citations

Cloning and Expression of a Cocaine-Sensitive Rat Dopamine Transporter

1991 • 587 citations

Cloning and Expression of a Cocaine-Sensitive Dopamine Transporter Complementary DNA

1991 • 584 citations

Mechanism of Transport and Storage of Neurotransmitter

1987 • 471 citations

Glutamate receptor desensitization and its role in synaptic transmission

1989 • 459 citations

Transport and Metabolism of Glutamate and Gaba in Neurons and Glial Cells

1981 • 437 citations

Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells

1987 • 430 citations

An [Na+ + K+]coupledl-glutamate transporter purified from rat brain is located in glial cell processes

1992 • 429 citations

Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors

1992 • 428 citations

Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family

1993 • 387 citations

Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells

1989 • 375 citations

The glial cell glutamate uptake carrier countertransports pH-changing anions

1992 • 372 citations

Cloning of the cDNa for a Na+/myo-inositol cotransporter, a hypertonicity stress protein.

1992 • 336 citations

Electrogenic glutamate uptake in glial cells is activated by intracellular potassium

1988 • 325 citations

Synaptic vesicles immunoisolated from rat cerebral cortex contain high levels of glutamate

1989 • 297 citations

The role of protein kinase C in long-term potentiation: a testable model

1989 • 278 citations

Molecular cloning and expression of a high affinity l -proline transporter expressed in putative glutamatergic pathways of rat brain

1992 • 239 citations

Amino acid neurotransmission: spotlight on synaptic vesicles

1990 • 237 citations

Quisqualate Activates a Rapidly Inactivating High Conductance Ionic Channel in Hippocampal Neurons

1989 • 237 citations

Site-directed mutagenesis of alpha 2A-adrenergic receptors: identification of amino acids involved in ligand binding and receptor activation by agonists.

1991 • 221 citations

Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters

1993 • 219 citations

Purification and reconstitution of the sodium- and potassium-coupled glutamate transport glycoprotein from rat brain

1990 • 216 citations

The neuroexcitotoxic amino acids glutamate and aspartate are altered in the spinal cord and brain in amyotrophic lateral sclerosis

1988 • 210 citations

Adenosine triphosphate-dependent uptake of glutamate into protein I-associated synaptic vesicles.

1983 • 206 citations

Electrogenic uptake of glutamate and aspartate into glial cells isolated from the salamander (Ambystoma) retina.

1991 • 194 citations

Characterization of a Na+/glucose cotransporter cloned from rabbit small intestine

1989 • 170 citations

The Ca²⁺/Cl⁻ dependent L‐[³H]glutamate binding: a new receptor or a particular transport process?

1984 • 169 citations

Cloning and functional expression of a mammalian Na+/nucleoside cotransporter. A member of the SGLT family.

1992 • 163 citations

Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter

1992 • 160 citations

Pharmacologically distinct sodium-dependentl-[3H]glutamate transport processes in rat brain

1991 • 152 citations

Cloning and expression of a mammalian Na+/amino acid cotransporter with sequence similarity to Na+/glucose cotransporters.

1993 • 136 citations

Glutamate transporters from brain

1993 • 125 citations

Identification and sequence analysis of the Rhizobium meliloti dctA gene encoding the C4-dicarboxylate carrier

1989 • 122 citations

Glutamate and other CSF amino acids in Alzheimer's disease

1992 • 121 citations

Excitatory amino acid-releasing and cholinergic neurones in Alzheimer's disease

1986 • 118 citations

Utilization of alpha-ketoglutarate as a precursor for transmitter glutamate in cultured cerebellar granule cells

1991 • 110 citations

Counterflow of L-glutamate in plasma membrane vesicles and reconstituted preparations from rat brain

1990 • 106 citations

Nucleotide sequence of gltS, the Na+/glutamate symport carrier gene of Escherichia coli B.

1990 • 100 citations

Aspartate transport in synaptosomes from rat brain.

1983 • 99 citations

Electrogenic L-glutamate uptake in Xenopus laevis oocytes expressing a cloned rat brain L-glutamate/L-aspartate transporter (GLAST-1)

1993 • 80 citations

What excitotoxin kills striatal neurons in Huntington's disease? Clues from neurochemical studies

1990 • 76 citations

Revised nucleotide sequence of the gltP gene, which encodes the proton-glutamate-aspartate transport protein of Escherichia coli K-12

1992 • 74 citations

Quisqualate‐sensitive, chloride‐dependent transport of glutamate into rat brain synaptosomes

1987 • 66 citations

The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis.

1993 • 65 citations

Low-affinity intestinal L-aspartate transport with 2:1 coupling stoichiometry for Na+/Asp

1988 • 47 citations

Renal transport of amino acids

1979 • 47 citations

The association of [3H]d-aspartate binding and high-affinity glutamate uptake in the human brain

1986 • 43 citations

Electroneutral Na+/dicarboxylic amino acid cotransport in rat intestinal brush border membrane vesicles

1982 • 42 citations

Mechanism of L-glutamate transport in membrane vesicles from Bacillus stearothermophilus

1989 • 40 citations

Glutamine and 2-oxoglutarate as metabolic precursors of the transmitter pools of glutamate and GABA: Correlation of regional uptake by rat brain synaptosomes

1989 • 40 citations

Acidic amino acid transport in animal cells and tissues

1987 • 36 citations

Transport of acidic amino acids by human jejunal brush-border membrane vesicles

1987 • 20 citations

Cation dependence of renal outer cortical brush border membrane L-glutamate transport

1985 • 18 citations

Calcium ions induce glutamate transport into rat brain membrane vesicles in the absence of sodium and chloride evidence for a novel uptake site?

1988 • 17 citations

Glutamate Transport and Not Glutamate Receptor Binding Is Stimulated by Gangliosides in a Ca²⁺‐Dependent Manner in Rat Brain Synaptic Plasma Membranes

1989 • 13 citations