Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1993 • 3,605 citations

Vascular endothelial growth factor (VEGF) and its receptors

1999 • 3,498 citations

Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix.

1996 • 1,747 citations

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

1996 • 1,355 citations

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1994 • 1,249 citations

Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma.

1996 • 1,206 citations

Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements.

1991 • 950 citations

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer

1995 • 622 citations

Translation of Vascular Endothelial Growth Factor mRNA by Internal Ribosome Entry: Implications for Translation under Hypoxia

1998 • 496 citations

Quantitation and prognostic value of breast cancer angiogenesis: Comparison of microvessel density, Chalkley count, and computer image analysis

1995 • 450 citations

Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast

1999 • 446 citations

Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism.

1993 • 411 citations

Macrophage responses to hypoxia: relevance to disease mechanisms

1999 • 391 citations

Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages.

1984 • 366 citations

Production of Vascular Endothelial Growth Factor by Murine Macrophages

1998 • 304 citations

Hypoxia-associated Induction of Early Growth Response-1 Gene Expression

1999 • 250 citations

Vascular Endothelial Cell Growth Factor–Induced Tissue Factor Expression in Endothelial Cells Is Mediated by EGR-1

1999 • 215 citations

Regulation of Human Vascular Endothelial Growth Factor mRNA Stability in Hypoxia by Heterogeneous Nuclear Ribonucleoprotein L

1999 • 209 citations

The macrophage – a novel system to deliver gene therapy to pathological hypoxia

2000 • 208 citations

Proliferation and hypoxia in human squamous cell carcinoma of the cervix: First report of combined immunohistochemical assays

1997 • 201 citations

Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids

1995 • 197 citations

Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor β-1

1998 • 193 citations

Response of tumour cells to hypoxia: role of p53 and NFkB

1998 • 181 citations

Drug Resistance in Oncology

1994 • 173 citations

Mechanical loading regulates expression of talin and its mRNA, which are concentrated at myotendinous junctions

1998 • 137 citations

Invasive lobular and invasive ductal carcinoma of the breast show distinct patterns of vascular endothelial growth factor expression and angiogenesis

1998 • 126 citations

Microenvironmental control of gene expression: Implications for tumor angiogenesis, progression, and metastasis

1998 • 97 citations

Validation of anti-vascular endothelial growth factor (anti-VEGF) antibodies for immunohistochemical localization of VEGF in tissue sections: expression of VEGF in the human endometrium

1998 • 71 citations

Production of VEGF and expression of the VEGF receptors Flt-1 and KDR in primary cultures of epithelial and stromal cells derived from breast tumours

1999 • 65 citations

Lactate stimulation of macrophage-derived angiogenic activity is associated with inhibition of Poly(ADP-ribose) synthesis.

1996 • 49 citations

Phenotypic characterization of macrophage subpopulations and localization of factor XIII in the stromal cells of carcinomas

1990 • 12 citations

Microregional tumour blood flow: heterogeneity and therapeutic significance

1997 • 6 citations

Mechanisms of stress-induced angiogenesis in tumours

1997 • 1 citations