Apobec-1 and apolipoprotein B mRNA editing

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

A Receptor-Mediated Pathway for Cholesterol Homeostasis

1986 • 5,638 citations

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1994 • 1,472 citations

The leucine-rich repeat: a versatile binding motif

1994 • 1,209 citations

A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine

1987 • 1,021 citations

Major transcript of the frameshifted coxll gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA

1986 • 809 citations

Apolipoprotein B-48 Is the Product of a Messenger RNA with an Organ-Specific In-Frame Stop Codon

1987 • 746 citations

Complete protein sequence and identification of structural domains of human apolipoprotein B

1986 • 620 citations

Molecular Cloning of an Apolipoprotein B Messenger RNA Editing Protein

1993 • 609 citations

A mammalian RNA editing enzyme

1996 • 512 citations

The C. elegans genome sequencing project: a beginning

1992 • 496 citations

Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing.

1994 • 435 citations

Atomic Structure of Adenosine Deaminase Complexed with a Transition-State Analog: Understanding Catalysis and Immunodeficiency Mutations

1991 • 430 citations

Sequence, structure, receptor-binding domains and internal repeats of human apolipoprotein B-100

1986 • 423 citations

Cytidine Deaminase. The 2·3 Å Crystal Structure of an Enzyme: Transition-state Analog Complex

1994 • 378 citations

Effects of ethanol on lipid metabolism.

1979 • 374 citations

Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals.

1995 • 286 citations

Apolipoprotein B mRNA editing in 12 different mammalian species: hepatic expression is reflected in low concentrations of apoB-containing plasma lipoproteins

1993 • 272 citations

RNA editing in the Wilms' tumor susceptibility gene, WT1.

1994 • 186 citations

Evolutionary origins of apoB mRNA editing: Catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site

1995 • 180 citations

An in vitro system for the editing of apolipoprotein B mRNA

1989 • 175 citations

Targeted Disruption of the Mouse apobec-1 Gene Abolishes Apolipoprotein B mRNA Editing and Eliminates Apolipoprotein B48

1996 • 152 citations

Phenotypic analysis of mice expressing exclusively apolipoprotein B48 or apolipoprotein B100.

1996 • 139 citations

Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene.

1994 • 137 citations

Mutagenesis of apobec-1, the Catalytic Subunit of the Mammalian Apolipoprotein B mRNA Editing Enzyme, Reveals Distinct Domains That Mediate Cytosine Nucleoside Deaminase, RNA Binding, and RNA Editing Activity

1995 • 133 citations

Biosynthesis of Apolipoprotein B48-containing Lipoproteins

1996 • 129 citations

Deduced amino acid sequence of Escherichia coli adenosine deaminase reveals evolutionarily conserved amino acid residues: implications for catalytic function

1991 • 129 citations

The Neurofibromatosis Type I Messenger RNA Undergoes Base-Modification RNA Editing

1996 • 128 citations

apobec-1, the Catalytic Subunit of the Mammalian Apolipoprotein B mRNA Editing Enzyme, Is a Novel RNA-binding Protein

1995 • 123 citations

Blasticidin S-resistance gene (bsr): A novel selectable marker for mammalian cells

1991 • 122 citations

RNA Editing: The alteration of protein coding sequences of RNA

1994 • 109 citations

In vitro apolipoprotein B mRNA editing: identification of a 27S editing complex.

1991 • 103 citations

Complete Phenotypic Characterization of apobec-1 Knockout Mice with a Wild-type Genetic Background and a Human Apolipoprotein B Transgenic Background, and Restoration of Apolipoprotein B mRNA Editing by Somatic Gene Transfer of Apobec-1

1996 • 102 citations

Fasting decreases apolipoprotein B mRNA editing and the secretion of small molecular weight apoB by rat hepatocytes: evidence that the total amount of apoB secreted is regulated post-transcriptionally

1990 • 94 citations

Apolipoprotein B mRNA editing is associated with UV crosslinking of proteins to the editing site.

1993 • 92 citations

Alternative mRNA Splicing and Differential Promoter Utilization Determine Tissue-specific Expression of the Apolipoprotein B mRNA-editing Protein (Apobec1) Gene in Mice.

1995 • 90 citations

Apolipoprotein B mRNA editing: a new tier for the control of gene expression

1992 • 88 citations

Overexpression of APOBEC-1 Results in Mooring Sequence-dependent Promiscuous RNA Editing

1996 • 88 citations

Lipoprotein and receptor interactions in vivo

1995 • 87 citations

Site-specific Mutagenesis Demonstrates That Cysteine 4326 of Apolipoprotein B Is Required for Covalent Linkage with Apolipoprotein(a) in Vivo

1995 • 85 citations

Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism.

1996 • 84 citations

Testing the limits of protein-ligand binding discrimination with transition-state analogue inhibitors

1991 • 81 citations

Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein

1994 • 79 citations

Characterization of comE, a late competence operon of Bacillus subtilis required for the binding and uptake of transforming DNA

1993 • 76 citations

The nucleoside deaminases for cytidine and adenosine: Structure, transition state stabilization, mechanism, and evolution

1995 • 75 citations

Cytidine Deaminase Complexed to 3-Deazacytidine: A “Valence Buffer” in Zinc Enzyme Catalysis

1996 • 70 citations

A 40 kilodalton rat liver nuclear protein binds specifically to apolipoprotein B mRNA around the RNA editing site

1990 • 68 citations

Insulin promotes the biosynthesis and secretion of apolipoprotein B-48 by altering apolipoprotein B mRNA editing.

1994 • 61 citations

Hyperediting of Multiple Cytidines of Apolipoprotein B mRNA by APOBEC-1 Requires Auxiliary Protein(s) but Not a Mooring Sequence Motif

1996 • 60 citations

Chromosomal location, cloning and nucleotide sequence of the Bacillus subtilis cdd gene encoding cytidine/deoxycytidine deaminase

1989 • 59 citations

Cloning of a Functional cDNA for Human Cytidine Deaminase (CDD) and Its Use as a Marker of Monocyte/Macrophage Differentiation

1993 • 58 citations

Cloning and nucleotide sequence of the Escherichia coli cytidine deaminase (ccd) gene

1992 • 52 citations

Insertional disruption of the nusB (ssyB) gene leads to cold-sensitive growth of Escherichia coli and suppression of the secY24 mutation

1992 • 50 citations

RNA editing: Exploring one mode with apolipoprotein B mRNA

1993 • 49 citations

Structural relationship of human apolipoprotein B48 to apolipoprotein B100.

1987 • 46 citations

Ethanol modulates apolipoprotein B mRNA editing in the rat.

1996 • 45 citations

Apolipoprotein B messenger RNA editing: insights into the molecular regulation of post-transcriptional cytidine deamination

1995 • 44 citations

The apolipoprotein B messenger RNA editing enzyme

1994 • 34 citations

Role of Glutamate-104 in Generating a Transition State Analogue Inhibitor at the Active Site of Cytidine Deaminase

1996 • 33 citations

Identification of Mycoplasma pirum genes involved in the salvage pathways for nucleosides

1993 • 23 citations

Editing of human α-galactosidase RNA resulting in a pyrimidine top purine conversion

1995 • 22 citations

In vitro apolipoprotein B mRNA editing activity can be modulated by fasting and refeeding rats with a high carbohydrate diet

1992 • 17 citations

Increased proportion of plasma apoB-48 to apoB-100 in non-insulin-dependent diabetic rats: contribution of enhanced apoB mRNA editing in the liver.

1995 • 13 citations