How should physicians view heart failure? The philosophical and physiological evolution of three conceptual models of the disease

Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)

1988 • 3,818 citations

A Comparison of Enalapril with Hydralazine–Isosorbide Dinitrate in the Treatment of Chronic Congestive Heart Failure

1991 • 2,867 citations

Prevalence of Total Coronary Occlusion during the Early Hours of Transmural Myocardial Infarction

1980 • 2,722 citations

Effect of Vasodilator Therapy on Mortality in Chronic Congestive Heart Failure

1986 • 2,409 citations

Effect of Oral Milrinone on Mortality in Severe Chronic Heart Failure

1991 • 2,186 citations

A double‐blind, placebo‐controlled trial

1986 • 1,281 citations

Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group.

1990 • 1,151 citations

Effect of Captopril on Progressive Ventricular Dilatation after Anterior Myocardial Infarction

1988 • 1,119 citations

Adrenergic effects on the biology of the adult mammalian cardiocyte.

1992 • 873 citations

Coronary Vasospasm as a Possible Cause of Myocardial Infarction

1978 • 845 citations

The Effect of Diltiazem on Mortality and Reinfarction after Myocardial Infarction

1988 • 793 citations

Survival after an experimental myocardial infarction: beneficial effects of long-term therapy with captopril.

1985 • 726 citations

Medical Therapy of Acute Myocardial Infarction by Application of Hemodynamic Subsets

1976 • 644 citations

Afterload mismatch and preload reserve: A conceptual framework for the analysis of ventricular function

1976 • 634 citations

Comparative Effects of Therapy With Captopril and Digoxin in Patients With Mild to Moderate Heart Failure

1988 • 579 citations

A placebo-controlled trial of captopril in refractory chronic congestive heart failure

1983 • 562 citations

A Comparison of Oral Milrinone, Digoxin, and Their Combination in the Treatment of Patients with Chronic Heart Failure

1989 • 561 citations

Diltiazem and Reinfarction in Patients with Non-Q-Wave Myocardial Infarction

1986 • 539 citations

The effect of diltiazem on mortality and reinfarction after myocardial infarction

1989 • 513 citations

Diltiazem increases late-onset congestive heart failure in postinfarction patients with early reduction in ejection fraction. The Adverse Experience Committee; and the Multicenter Diltiazem Postinfarction Research Group.

1991 • 510 citations

Correlates and prognostic implication of exercise capacity in chronic congestive heart failure

1985 • 505 citations

Pathophysiology of chronic heart failure

1992 • 478 citations

IMPROVED LEFT VENTRICULAR FUNCTION DURING NITROPRUSSIDE INFUSION IN ACUTE MYOCARDIAL INFARCTION

1972 • 461 citations

Exercise intolerance in patients with chronic heart failure: role of impaired nutritive flow to skeletal muscle.

1984 • 454 citations

Improvement in symptoms and exercise tolerance by metoprolol in patients with dilated cardiomyopathy: a double-blind, randomized, placebo-controlled trial.

1985 • 443 citations

DOUBLE-BLIND COMPARISON OF CAPTOPRIL ALONE AGAINST FRUSEMIDE PLUS AMILORIDE IN MILD HEART FAILURE

1987 • 429 citations

Calcium channel blockers in acute myocardial infarction and unstable angina: an overview.

1989 • 424 citations

Effect of propranolol after acute myocardial infarction in patients with congestive heart failure.

1986 • 416 citations

Medical Therapy of Acute Myocardial Infarction by Application of Hemodynamic Subsets

1976 • 393 citations

Captopril in heart failure. A double blind controlled trial.

1984 • 385 citations

Cardiac myocyte necrosis induced by angiotensin II.

1991 • 383 citations

Sympathoinhibitory responses to digitalis glycosides in heart failure patients. Direct evidence from sympathetic neural recordings.

1989 • 383 citations

Alterations in vasomotor tone in congestive heart failure

1982 • 369 citations

A prospective, randomized, double-blind, crossover study to compare the efficacy and safety of chronic nifedipine therapy with that of isosorbide dinitrate and their combination in the treatment of chronic congestive heart failure.

1990 • 348 citations

Medical therapy of acute myocardial infarction by application of hemodynamic subsets

1976 • 332 citations

Multicenter trial of oral enoximone in patients with moderate to moderately severe congestive heart failure. Lack of benefit compared with placebo. Enoximone Multicenter Trial Group.

1990 • 328 citations

Understanding the coronary circulation through studies at the microvascular level.

1990 • 326 citations

Vasodilator Therapy for Heart Failure

1973 • 301 citations

Oral hydralazine therapy for chronic refractory heart failure.

1976 • 299 citations

Improved exercise capacity and differing arterial and venous tolerance during chronic isosorbide dinitrate therapy for congestive heart failure.

1983 • 295 citations

Effects of enalapril in heart failure: a double blind study of effects on exercise performance, renal function, hormones, and metabolic state.

1985 • 281 citations

The Study of Left Ventricular Function in Man by Increasing Resistance to Ventricular Ejection with Angiotensin

1964 • 281 citations

A controlled trial of digoxin in congestive heart failure

1988 • 271 citations

Enalapril in patients with chronic heart failure: a placebo-controlled, randomized, double-blind study.

1984 • 267 citations

Diseases of the Heart

2001 • 263 citations

Sustained Reduction of Cardiac Impedance and Preload in Congestive Heart Failure with the Antihypertensive Vasodilator Prazosin

1977 • 262 citations

Effect of Short-Term Infusion of Sodium Nitroprusside on Mortality Rate in Acute Myocardial Infarction Complicated by Left Ventricular Failure

1982 • 256 citations

Contrasting peripheral short-term and long-term effects of converting enzyme inhibition in patients with congestive heart failure. A double-blind, placebo-controlled trial.

1989 • 246 citations

Long-term β-Blocker vasodilator therapy improves cardiac function in idiopathic dilated cardiomyopathy: A double-blind, randomized study of bucindolol versus placebo

1990 • 245 citations

Controlled trial of captopril in chronic heart failure: a rest and exercise hemodynamic study.

1983 • 234 citations

Hemodynamic and clinical limitations of long-term inotropic therapy with amrinone in patients with severe chronic heart failure.

1984 • 233 citations

A Comparison of Regional Blood Flow and Oxygen Utilization During Dynamic Forearm Exercise in Normal Subjects and Patients with Congestive Heart Failure

1974 • 233 citations

Propranolol in the Treatment of Acute Myocardial Infarction

1974 • 226 citations

Importance of the adrenergic nervous system in the support of circulatory function in patients with congestive heart failure

1963 • 218 citations

Long-term oral administration of amrinone for congestive heart failure: lack of efficacy in a multicenter controlled trial.

1985 • 204 citations

A COORDINATED APPROACH TO CHILDREN'S HEALTH IN INDIA

1981 • 197 citations

Role of neurohormonal mechanisms in determining survival in patients with severe chronic heart failure.

1987 • 197 citations

Beneficial effects of pimobendan on exercise tolerance and quality of life in patients with heart failure. Results of a multicenter trial. The Pimobendan Multicenter Research Group.

1992 • 195 citations

Exercise ventilation and pulmonary artery wedge pressure in chronic stable congestive heart failure

1986 • 183 citations

Contrasting immediate and long-term effects of isosorbide dinitrate on exercise capacity in congestive heart failure

1980 • 178 citations

Treatise on the Diseases of the Heart, and Great Vessels

2017 • 173 citations

Nitrate Therapy for Congestive Heart Failure

1978 • 173 citations

Reduction in Myocardial Ischemia with Nitroglycerin or Nitroglycerin plus Phenylephrine Administered during Acute Myocardial Infarction

1975 • 173 citations

Sodium and water balance in chronic congestive heart failure.

1986 • 172 citations

Hemodynamic and metabolic effects of isosorbide dinitrate in chronic congestive heart failure

1975 • 161 citations

Haemodynamic effects of nifedipine in heart failure.

1980 • 143 citations

Minoxidil in patients with chronic left heart failure: contrasting hemodynamic and clinical effects in a controlled trial.

1984 • 137 citations

Acute and long-term effects of enalapril on the cardiovascular response to exercise and exercise tolerance in patients with congestive heart failure

1985 • 133 citations

Renal Response to Captopril in Severe Heart Failure: Role of Furosemide in Natriuresis and Reversal of Hyponatremia

1984 • 132 citations

Double-blind, placebo-controlled study of the efficacy of flosequinan in patients with chronic heart failure

1993 • 122 citations

Coronary Arteries in Fatal Acute Myocardial Infarction

1972 • 117 citations

Afterload reduction: a comparison of captopril and nifedipine in dilated cardiomyopathy.

1986 • 115 citations

Clinical importance of the renin-angiotensin system in chronic heart failure: double blind comparison of captopril and prazosin.

1985 • 114 citations

Sustained beneficial effects of oral amrinone on cardiac and renal function in patients with severe congestive heart failure

1980 • 106 citations

Dependence of enhanced maximal exercise performance on increased peak skeletal muscle perfusion during long-term captopril therapy in heart failure

1987 • 98 citations

Milrinone in congestive heart failure: Acute and chronic hemodynamic and clinical evaluation

1985 • 98 citations

Suppression of the renin-angiotensin system by intravenous digoxin in chronic congestive heart failure

1983 • 96 citations

Placebo-Controlled Study of Lisinopril in Congestive Heart Failure

1987 • 92 citations

Survival in congestive heart failure during treatment with drugs with positive inotropic actions.

1987 • 77 citations

Differential long-term intrarenal and neurohormonal effects of captopril and prazosin in patients with chronic congestive heart failure: importance of initial plasma renin activity.

1986 • 72 citations

Effects of minoxidil on hemodynamics in patients with congestive heart failure.

1981 • 62 citations

Usefulness of OPC-8212, a quinolinone derivative, for chronic congestive heart failure in patients with ischemic heart disease or idiopathic dilated cardiomyopathy

1991 • 61 citations

CAPTOPRIL THERAPY FOR HEART FAILURE

1982 • 61 citations

The Effects of Hexamethonium on Certain Manifestations of Congestive Heart Failure

1953 • 56 citations

Hemodynamic Effects of Digoxin in Latent Cardiac Failure

1962 • 53 citations

Beneficial effects of milrinone and enalapril on long-term survival of rats with healed myocardial infarction

1988 • 52 citations

Calcium channel blockers in congestive heart failure: Theoretic considerations and clinical experience

1985 • 41 citations

CORONARY OCCLUSION AND FATAL ANGINA PECTORIS

1933 • 40 citations

Acute hemodynamic effects of a new inotropic agent, OPC-8212, on severe congestive heart failure

1986 • 39 citations

The hemodynamic effects of ouabain upon the diseased left ventricle

1968 • 34 citations

Evaluation of a new inotropic agent, OPC-8212, in patients with dilated cardiomyopathy and heart failure

1988 • 32 citations

Role of the sympathetic nervous system in chronic heart failure. A historical and philosophical perspective.

1990 • 32 citations

Prolonging life in patients with congestive heart failure: the next frontier. Introduction.

1987 • 30 citations

OPC-8212 in the treatment of congestive heart failure: Results of a pilot study

1988 • 29 citations

Nebivolol Increases Survival in Cardiomyopathic Hamsters with Congestive Heart Failure

1991 • 25 citations

Effects of milrinone on left ventricular remodeling after acute myocardial infarction.

1991 • 22 citations

USE OF INTRAVENOUSLY GIVEN GANGLIONIC BLOCKING AGENTS FOR ACUTE PULMONARY EDEMA

1956 • 19 citations

Deleted Work

1955 • 0 citations

Cited By (0)

Loading...