Evaluation of a new inotropic agent, OPC-8212, in patients with dilated cardiomyopathy and heart failure

An Introduction to Statistical Methods and Data Analysis

1994 • 5,244 citations

A new method for detecting anaerobic threshold by gas exchange

1986 • 3,936 citations

Lack of correlation between exercise capacity and indexes of resting left ventricular performance in heart failure

1981 • 899 citations

Exercise cardiac output is maintained with advancing age in healthy human subjects: cardiac dilatation and increased stroke volume compensate for a diminished heart rate.

1984 • 653 citations

A placebo-controlled trial of captopril in refractory chronic congestive heart failure

1983 • 562 citations

An Introduction to Statistical Methods and Data Analysis

1989 • 336 citations

Functional capacity of patients with chronic left ventricular failure

1979 • 273 citations

Measurement of absolute left ventricular volume from gated blood pool studies.

1982 • 264 citations

Effects of new inotropic agents on cyclic nucleotide metabolism and calcium transients in canine ventricular muscle.

1986 • 175 citations

Sustained hemodynamic and clinical effects of a new cardiotonic agent, WIN 47203, in patients with severe congestive heart failure.

1983 • 147 citations

Membrane current changes responsible for the positive inotropic effect of OPC-8212, a new positive inotropic agent, in single ventricular cells of the guinea pig heart.

1987 • 89 citations

Application of a frequency definition of ventricular proarrhythmia

1987 • 66 citations

Validity of left-ventricular ejection fractions measured at rest and peak exercise by equilibrium radionuclide angiography using short acquisition times.

1979 • 56 citations

Changes in left ventricular function during recovery from upright bicycle exercise in normal persons and patients with coronary artery disease

1986 • 46 citations

In vitro and in vivo studies of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, in various animals.

1984 • 43 citations

Enoximone (MDL 17,043) for stable, chronic heart failure secondary to ischemic or idiopathic cardiomyopathy

1986 • 42 citations

Evidence for possible increase of sodium channel open time and involvement of Na/Ca exchange by a new positive inotropic drug: OPC-8212

1985 • 39 citations

Acute hemodynamic effects of a new inotropic agent, OPC-8212, on severe congestive heart failure

1986 • 39 citations

Effects of amrinone on experimental acute myocardial ischaemic injury

1980 • 37 citations

New hope for the failing heart

1982 • 22 citations

Acute Hemodynamic Effects of a New Positive Inotropic Agent, 3,4-Dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-quinolinone (OPC-8212), in Conscious and Anesthetized Dogs

1986 • 18 citations

Involvement of cyclic AMP in the positive inotropic effect of OPC-8212, a new cardiotonic agent, on the canine ventricular muscle.

1984 • 17 citations

Studies on the mechanism of action of 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212), a new positive inotropic drug. Enzyme activities and Ca2+ transport processes of sarcolemma and intracellular organelles.

1984 • 9 citations

Effects of OPC-8212, a New Positive Inotropic Agent, and Dobutamine on Left Ventricular Global and Ischemic Regional Functions and Coronary Hemodynamics Under Coronary Artery Stenosis

1986 • 8 citations