Double-blind, placebo-controlled study of the efficacy of flosequinan in patients with chronic heart failure

Principles and procedures of statistics.

1960 • 22,587 citations

Principles and Procedures of Statistics

1961 • 18,011 citations

A Comparison of Enalapril with Hydralazine–Isosorbide Dinitrate in the Treatment of Chronic Congestive Heart Failure

1991 • 2,867 citations

Effect of Vasodilator Therapy on Mortality in Chronic Congestive Heart Failure

1986 • 2,409 citations

Effect of Oral Milrinone on Mortality in Severe Chronic Heart Failure

1991 • 2,186 citations

Comparative Effects of Therapy With Captopril and Digoxin in Patients With Mild to Moderate Heart Failure

1988 • 579 citations

A placebo-controlled trial of captopril in refractory chronic congestive heart failure

1983 • 562 citations

Prevention and Reversal of Nitrate Tolerance in Patients with Congestive Heart Failure

1987 • 366 citations

A prospective, randomized, double-blind, crossover study to compare the efficacy and safety of chronic nifedipine therapy with that of isosorbide dinitrate and their combination in the treatment of chronic congestive heart failure.

1990 • 348 citations

Vasodilator Therapy for Heart Failure

1973 • 301 citations

Hemodynamic advantage of combined administration of hydralazine orally and nitrates nonparenterally in the vasodilator therapy of chronic heart failure

1977 • 173 citations

Minoxidil in patients with chronic left heart failure: contrasting hemodynamic and clinical effects in a controlled trial.

1984 • 137 citations

Combined Oral Hydralazine-Nitrate Therapy in Left Ventricular Failure

1978 • 137 citations

Acute and long-term effects of enalapril on the cardiovascular response to exercise and exercise tolerance in patients with congestive heart failure

1985 • 133 citations

Hemodynamic Characterization of Tolerance to Long-Term Hydralazine Therapy in Severe Chronic Heart Failure

1982 • 101 citations

Chronic renal and neurohumoral effects of the calcium entry blocker nisoldipine in patients with congestive heart failure

1987 • 94 citations

Application of a frequency definition of ventricular proarrhythmia

1987 • 66 citations

Standardized Methods for Comparison of Sphygmomanometers

1984 • 64 citations

Positive inotropic effects of hydralazine in human subjects: Comparison with prazosin in the setting of congestive heart failure

1980 • 61 citations

Hemodynamic effects of BTS 49465, a new long-acting systemic vasodilator drug, in patients with severe congestive heart failure

1987 • 57 citations

The pharmacokinetics and haemodynamics of BTS 49465 and its major metabolite in healthy volunteers

1985 • 53 citations

Flosequinan in heart failure: acute haemodynamic and longer term symptomatic effects.

1988 • 51 citations

Effect of flosequinan on exercise capacity and symptoms in severe heart failure.

1989 • 50 citations

Role of the renin-angiotensin system in the development of hemodynamic and clinical tolerance to long-term prazosin therapy in patients with severe chronic heart failure

1986 • 45 citations

Randomized study to evaluate the relation between oral isosorbide dinitrate dosing interval and the development of early tolerance to its effect on left ventricular filling pressure in patients with chronic heart failure.

1991 • 41 citations

The effects of BTS 49465 on blood pressure and peripheral arteriolar and venous tone in normal volunteers.

1984 • 40 citations

Flosequinan: A vasodilator with positive inotropic activity

1991 • 28 citations

Hydralazine therapy in chronic congestive heart failure

1984 • 24 citations

The effects of flosequinan on endothelin-1-induced changes in inositol 1,4,5-trisphosphate levels and protein kinase C activity in rat aorta

1992 • 24 citations