A Role for SNAP25 in Internalization of Kainate Receptors and Synaptic Plasticity

SNAP receptors implicated in vesicle targeting and fusion

1993 • 3,220 citations

Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles

1985 • 1,425 citations

Neurotoxins Affecting Neuroexocytosis

2000 • 1,230 citations

Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus

1992 • 1,088 citations

Regulation of AMPA receptors during synaptic plasticity

2002 • 757 citations

Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors

1993 • 736 citations

Regulatory mechanisms of AMPA receptors in synaptic plasticity

2007 • 677 citations

Synaptic plasticity at hippocampal mossy fibre synapses

2005 • 624 citations

A nomenclature for ligand-gated ion channels

2008 • 577 citations

Clustering of AMPA Receptors by the Synaptic PDZ Domain–Containing Protein PICK1

1999 • 540 citations

The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits

1992 • 537 citations

Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain.

1989 • 513 citations

Design and implementation of bimolecular fluorescence complementation (BiFC) assays for the visualization of protein interactions in living cells

2006 • 511 citations

Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

1998 • 472 citations

Transgenic Inhibition of Synaptic Transmission Reveals Role of CA3 Output in Hippocampal Learning

2008 • 471 citations

Botulinum neurotoxins serotypes A and E cleave SNAP‐25 at distinct COOH‐terminal peptide bonds

1993 • 433 citations

Protein kinase C modulates NMDA receptor trafficking and gating

2001 • 418 citations

Roles and rules of kainate receptors in synaptic transmission

2003 • 365 citations

Adenosine A2A Receptors Are Essential for Long-Term Potentiation of NMDA-EPSCs at Hippocampal Mossy Fiber Synapses

2008 • 353 citations

Clostridial neurotoxins: new tools for dissecting exocytosis

1994 • 323 citations

PICK1 Targets Activated Protein Kinase Cα to AMPA Receptor Clusters in Spines of Hippocampal Neurons and Reduces Surface Levels of the AMPA-Type Glutamate Receptor Subunit 2

2001 • 322 citations

SNARE Interactions Are Not Selective

1999 • 322 citations

Receptor trafficking and the plasticity of excitatory synapses

2002 • 304 citations

Molecular characterization of synaptophysin, a major calcium-binding protein of the synaptic vesicle membrane.

1986 • 296 citations

Mutagenesis Reveals a Role for ABP/GRIP Binding to GluR2 in Synaptic Surface Accumulation of the AMPA Receptor

2000 • 295 citations

Kainate receptors and synaptic transmission

2003 • 277 citations

SAP90 Binds and Clusters Kainate Receptors Causing Incomplete Desensitization

1998 • 261 citations

Phosphorylation of Serine‐880 in GluR2 by Protein Kinase C Prevents Its C Terminus from Binding with Glutamate Receptor‐Interacting Protein

1999 • 260 citations

Postsynaptic Positioning of Endocytic Zones and AMPA Receptor Cycling by Physical Coupling of Dynamin-3 to Homer

2007 • 254 citations

Calcium-Permeable AMPA Receptor Plasticity Is Mediated by Subunit-Specific Interactions with PICK1 and NSF

2005 • 251 citations

Specific Interaction of the PDZ Domain Protein PICK1 with the COOH Terminus of Protein Kinase C-α

1997 • 247 citations

GPS: a comprehensive www server for phosphorylation sites prediction

2005 • 241 citations

Developmental and activity- dependent regulation of kainate receptors at thalamocortical synapses

1999 • 227 citations

Cargo recognition during clathrin-mediated endocytosis: a team effort

2004 • 226 citations

Rapid and Differential Regulation of AMPA and Kainate Receptors at Hippocampal Mossy Fibre Synapses by PICK1 and GRIP

2003 • 213 citations

GluR5 and GluR6 Kainate Receptor Subunits Coexist in Hippocampal Neurons and Coassemble to Form Functional Receptors

2000 • 186 citations

Regulation of Synaptic Strength and AMPA Receptor Subunit Composition by PICK1

2004 • 185 citations

SNAREs and the specificity of membrane fusion

2001 • 175 citations

Tetanus and botulinum neurotoxins: turning bad guys into good by research

2001 • 173 citations

Homotypic fusion of early endosomes: SNAREs do not determine fusion specificity

2006 • 152 citations

Loss of Kainate Receptor-Mediated Heterosynaptic Facilitation of Mossy-Fiber Synapses in KA2^−/−Mice

2003 • 151 citations

Distribution of Kainate Receptor Subunits at Hippocampal Mossy Fiber Synapses

2003 • 145 citations

A new form of long-term depression in the perirhinal cortex

2000 • 142 citations

Long-Term Potentiation Selectively Expressed by NMDA Receptors at Hippocampal Mossy Fiber Synapses

2008 • 142 citations

Bimolecular Fluorescence Complementation: Visualization of Molecular Interactions in Living Cells

2008 • 135 citations

A Mosaic of Functional Kainate Receptors in Hippocampal Interneurons

2004 • 129 citations

Heteromeric Kainate Receptors Formed by the Coassembly of GluR5, GluR6, and GluR7

1999 • 125 citations

Multiple Trafficking Signals Regulate Kainate Receptor KA2 Subunit Surface Expression

2003 • 119 citations

Activity-dependent endocytic sorting of kainate receptors to recycling or degradation pathways

2004 • 117 citations

Subunit Composition and Alternative Splicing Regulate Membrane Delivery of Kainate Receptors

2004 • 101 citations

Metabotropic Glutamate Receptor-Mediated LTD Involves Two Interacting Ca2+ Sensors, NCS-1 and PICK1

2008 • 95 citations

Hrs regulates early endosome fusion by inhibiting formation of an endosomal SNARE complex

2003 • 94 citations

Coassembly of Two GluR6 Kainate Receptor Splice Variants within a Functional Protein Complex

2005 • 84 citations

Nuclear accumulation of Smad complexes occurs only after the midblastula transition inXenopus

2007 • 77 citations

Long-Term Depression of Kainate Receptor-Mediated Synaptic Transmission

2006 • 63 citations

Snap-25 is polarized to axons and abundant along the axolemma: an immunogold study of intact neurons.

2000 • 60 citations

PKC-dependent autoregulation of membrane kainate receptors

2007 • 51 citations

Small peptides patterned after the N‐terminus domain of SNAP25 inhibit SNARE complex assembly and regulated exocytosis

2003 • 44 citations

Postsynaptic density antigens: preparation and characterization of an antiserum against postsynaptic densities

1981 • 36 citations

Ca2+ and N-Ethylmaleimide-sensitive Factor Differentially Regulate Disassembly of SNARE Complexes on Early Endosomes

2004 • 26 citations

CytLEK1 Is a Regulator of Plasma Membrane Recycling through Its Interaction with SNAP-25

2006 • 20 citations

Human autoantibodies against early endosome antigen-1 enhance excitatory synaptic transmission

2006 • 17 citations

Visualizing protein interactions by bimolecular fluorescence complementation in Xenopus

2008 • 15 citations

Synaptic vesicle fusion and synaptotagmin: 2B or not 2B?

2002 • 8 citations