Ca2+/Calmodulin-dependent Protein Kinase Cascade in Caenorhabditis elegans

THE GENETICS OF CAENORHABDITIS ELEGANS

1974 • 14,589 citations

CREB: a Ca ²⁺ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases

1991 • 1,476 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

Solution structure of a calmodulin-target peptide complex by multidimensional NMR

1992 • 1,258 citations

Regulation of Gene Expression in Hippocampal Neurons by Distinct Calcium Signaling Pathways

1993 • 1,165 citations

CREB Phosphorylation and Dephosphorylation: A Ca2+- and Stimulus Duration–Dependent Switch for Hippocampal Gene Expression

1996 • 1,109 citations

Target Enzyme Recognition by Calmodulin: 2.4 Å Structure of a Calmodulin-Peptide Complex

1992 • 1,031 citations

Neurobiology of the Caenorhabditis elegans Genome

1998 • 912 citations

The Multifunctional Calcium/Calmodulin-Dependent Protein Kinase: From Form to Function

1995 • 812 citations

Molecular and Structural Basis of Target Recognition by Calmodulin

1995 • 752 citations

Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity.

1994 • 718 citations

Modulation of Calmodulin Plasticity in Molecular Recognition on the Basis of X-Ray Structures

1993 • 615 citations

Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

1998 • 612 citations

PROTEIN KINASES IN THE BRAIN

1985 • 559 citations

Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.

1994 • 542 citations

Characterization of Ca2+/calmodulin-dependent protein kinase IV. Role in transcriptional regulation.

1994 • 370 citations

Alternative splicing introduces a nuclear localization signal that targets multifunctional CaM kinase to the nucleus.

1994 • 251 citations

Components of a Calmodulin-dependent Protein Kinase Cascade

1998 • 249 citations

Characterization of a Ca2+/Calmodulin-dependent Protein Kinase Cascade

1995 • 221 citations

Nuclear and axonal localization of Ca2+/calmodulin-dependent protein kinase type Gr in rat cerebellar cortex.

1991 • 206 citations

Regulation of Activating Transcription Factor-1 and the cAMP Response Element-binding Protein by Ca2+/Calmodulin-dependent Protein Kinases Type I, II, and IV

1996 • 195 citations

Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase.

1995 • 182 citations

Activation mechanisms for Ca2+/calmodulin-dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase.

1994 • 150 citations

An Expression System of Rat Calmodulin Using T7 Phage Promoter inEscherichia coli

1998 • 141 citations

Activating transcription factor-1 can mediate Ca(2+)- and cAMP-inducible transcriptional activation.

1993 • 137 citations

Phosphorylation and Activation of Ca2+-Calmodulin-dependent Protein Kinase IV by Ca2+-Calmodulin-dependent Protein Kinase Ia Kinase

1995 • 137 citations

Purification and characterization of a brain-specific multifunctional calmodulin-dependent protein kinase from rat cerebellum.

1992 • 131 citations

Biochemical characterization of the multifunctional Ca2+/calmodulin-dependent protein kinase type IV expressed in insect cells.

1993 • 125 citations

Requirements for Calcium and Calmodulin in the Calmodulin Kinase Activation Cascade

1996 • 122 citations

Activation of Ca2+/Calmodulin-dependent Protein Kinase (CaM-kinase) IV by CaM-kinase Kinase in Jurkat T Lymphocytes

1995 • 111 citations

Calcium/calmodulin-dependent protein kinase I. cDNA cloning and identification of autophosphorylation site.

1993 • 104 citations

Immunochemical localization of calcium/calmodulin‐dependent protein kinase I

1995 • 102 citations

Multiple Ca2+-Calmodulin-dependent Protein Kinase Kinases from Rat Brain

1996 • 96 citations

Molecular Cloning of Ca2+/Calmodulin-Dependent Protein Kinase Kinase

1997 • 81 citations

A protein activator of Ca(2+)-calmodulin-dependent protein kinase Ia.

1994 • 80 citations

Characterization of the Mechanism of Regulation of Ca2+/ Calmodulin-dependent Protein Kinase I by Calmodulin and by Ca2+/Calmodulin-dependent Protein Kinase Kinase

1998 • 78 citations

Defective Survival and Activation of Thymocytes in Transgenic Mice Expressing a Catalytically Inactive Form of Ca2+/Calmodulin-Dependent Protein Kinase IV

1997 • 78 citations

The Regulatory Region of Calcium/Calmodulin-dependent Protein Kinase I Contains Closely Associated Autoinhibitory and Calmodulin-binding Domains

1995 • 71 citations

Calcium/Calmodulin-Dependent Protein Kinase Kinase: Identification of Regulatory Domains

1997 • 67 citations

Structure and regulation of calcium/calmodulin-dependent protein kinases II and IV

1996 • 61 citations

Requirement of Brain Extract for the Activity of Brain Calmodulin-Dependent Protein Kinase IV Expressed in Escherichia coli1

1993 • 58 citations

Purification and Characterization of Ca2+/Calmodulin-Dependent Protein Kinase IV Kinase from Rat Brain1

1994 • 57 citations

Substrate Recognition by Ca2+/Calmodulin-dependent Protein Kinase Kinase

1999 • 57 citations

Activation of a Calcium-Calmodulin-dependent Protein Kinase I Cascade in PC12 Cells

1996 • 40 citations

Characterization of a rat cDNA clone encoding calcium/calmodulin-dependent protein kinase I

1994 • 24 citations

Purification and Characterization of a Novel Protein Activator of Ca2+/Calmodulin-Dependent Protein Kinase I

1995 • 9 citations