Bone marrow stromal cells as a vehicle for gene transfer

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

The Basic Science of Gene Therapy

1993 • 1,767 citations

Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta

1998 • 559 citations

Host origin of marrow stromal cells following allogeneic bone marrow transplantation

1987 • 323 citations

Hematology: Basic Principles and Practice

1991 • 299 citations

Donor origin of the in vitro haematopoietic microenvironment after marrow transplantation in man

1982 • 255 citations

The use of DNA viruses as vectors for gene therapy.

1994 • 206 citations

Biology of Bone Marrow Stroma

1995 • 186 citations

Lymphocytes as cellular vehicles for gene therapy in mouse and man.

1991 • 138 citations

Origin of Human Bone Marrow Fibroblasts

1980 • 124 citations

Potential Adhesion Mechanisms for Localisation of Haemopoietic Progenitors to Bone Marrow Stroma

1994 • 108 citations

Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice.

1990 • 107 citations

Infection of Human Marrow Stroma by Human Immunodeficiency Virus-1 (HIV-1) Is Both Required and Sufficient for HIV-1–Induced Hematopoietic Suppression In Vitro: Demonstration by Gene Modification of Primary Human Stroma

1997 • 104 citations

Bone Marrow Stromal Cells as Targets for Gene Therapy of Hemophilia A

1998 • 75 citations

Transplantation of bone marrow fibroblastoid stromal cells in mice via the intravenous route

1983 • 73 citations

Precise gene dosage determination by polymerase chain reaction: theory, methodology, and statistical approach

1991 • 60 citations

CYTOGENETIC STUDIES ON BONE MARROW FIBROBLASTS FROM A MALE-FEMALE HEMATOPOIETIC CHIMERA

1978 • 49 citations

Osteoprogenitor Cells as Targets for Ex Vivo Gene Transfer

1998 • 43 citations

Retroviral Vector-Modified Bone Marrow Stromal Cells Secrete Biologically Active Factor IXIn Vitroand Transiently Deliver Therapeutic Levels of Human Factor IX to the Plasma of Dogs after Reinfusion

1998 • 37 citations

Reduced expression of vascular cell adhesion molecule-1 on bone marrow stromal cells isolated from marrow transplant recipients correlates with a reduced capacity to support human B lymphopoiesis in vitro

1995 • 35 citations

In vitro and in vivo studies of stromal niches.

1994 • 32 citations

Long-Term Expression of Retroviral-Transduced Adenosine Deaminase in Human Primitive Hematopoietic Progenitors

1993 • 31 citations

The hematopoietic stromal microenvironment promotes retro‐virus‐mediated gene transfer into hematopoietic stem cells

1993 • 31 citations

In Vivo Hepatocyte Transduction with Retrovirus during In-flow Occlusion

1993 • 29 citations

Role of stromal cells and macrophages in fibronectin biosynthesis and matrix assembly in human long-term marrow cultures

1993 • 28 citations

Role of stromal cells and macrophages in fibronectin biosynthesis and matrix assembly in human long-term marrow cultures

1993 • 25 citations

Bead transfection: rapid and efficient gene transfer into marrow stromal and other adherent mammalian cells.

1993 • 23 citations

Cord Blood Transplantation and the Potential for Gene Therapy

1995 • 16 citations

Morphological characterization of stromal cell types in hematopoietically active long-term murine bone marrow cultures.

1995 • 14 citations

Homing and immunogenicity of murine stromal cells transfected with xenogeneic MHC class II genes

1995 • 13 citations

Homing and Immunogenicity of Murine Stromal Cells Transfected with Xenogeneic Mhc Class II Genes

1995 • 5 citations