Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta

Mesenchymal stem cells

1991 • 6,355 citations

Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues

1997 • 4,643 citations

The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid

1961 • 3,860 citations

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

Bone marrow transplant

1999 • 2,452 citations

Fibroblast precursors in normal and irradiated mouse hematopoietic organs.

1976 • 1,638 citations

Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation

1997 • 1,471 citations

Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.

1988 • 1,334 citations

Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1

1991 • 1,144 citations

Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5‐azacytidine

1995 • 1,097 citations

Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice

1997 • 1,020 citations

Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice.

1995 • 922 citations

Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures

1992 • 829 citations

Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone.

1994 • 627 citations

Induction of Rapid Osteoblast Differentiation in Rat Bone Marrow Stromal Cell Cultures by Dexamethasone and BMP-2

1994 • 533 citations

Isolation and characterization of osteoblast precursor cells from human bone marrow

1996 • 397 citations

Host origin of marrow stromal cells following allogeneic bone marrow transplantation

1987 • 323 citations

Donor origin of the in vitro haematopoietic microenvironment after marrow transplantation in man

1982 • 255 citations

Regulation of human bone marrow-derived osteoprogenitor cells by osteogenic growth factors.

1995 • 228 citations

Origin of bone marrow stromal mechanocytes in radiochimeras and heterotopic transplants.

1978 • 196 citations

Biology of Bone Marrow Stroma

1995 • 186 citations

Stromal cells in long-term cultures: keys to the elucidation of hematopoietic development?

1993 • 168 citations

The extracellular matrix of the hematopoietic microenvironment

1995 • 162 citations

Engraftment of a clonal bone marrow stromal cell line in vivo stimulates hematopoietic recovery from total body irradiation.

1987 • 159 citations

Cell and molecular biology of vertebrate hard tissues.

1988 • 156 citations

Molecular cloning and sequence analysis of a mouse Y chromosome RNA transcript expressed in the test is

1987 • 115 citations

Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice.

1990 • 107 citations

Identification of a minimal sequence of the mouse pro-alpha 1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts.

1996 • 103 citations

The Biology and Application of Human Bone Marrow Stromal Cell Precursors

1996 • 102 citations

Transgenic mice that express a mini-gene version of the human gene for type I procollagen (COL1A1) develop a phenotype resembling a lethal form of osteogenesis imperfecta.

1991 • 96 citations

Development of osteogenic tissue in diffusion chambers from early precursor cells in bone marrow of adult rats

1987 • 92 citations

Host origin of the human hematopoietic microenvironment following allogeneic bone marrow transplantation

1987 • 75 citations

Transplantation of bone marrow fibroblastoid stromal cells in mice via the intravenous route

1983 • 73 citations

Transgenic mice expressing a partially deleted gene for type I procollagen (COL1A1). A breeding line with a phenotype of spontaneous fractures and decreased bone collagen and mineral.

1993 • 70 citations

Identification and Characterization of the Insulin-like Growth Factor I Receptor in Mature Rabbit Osteoclasts

1997 • 67 citations

Phenotypic heterogeneity in osteogenesis imperfecta: the mildly affected mother of a proband with a lethal variant has the same mutation substituting cysteine for alpha 1-glycine 904 in a type I procollagen gene (COL1A1).

1990 • 54 citations

Probing immune functions in RAG-deficient mice

1994 • 51 citations

Bone marrow stromal cells contribute to synovial cell proliferation in rats with collagen induced arthritis.

1996 • 45 citations

Changes in the growth properties of CD34+, CD38- bone marrow progenitors during human fetal development

1995 • 43 citations

Osteoprogenitor Cells as Targets for Ex Vivo Gene Transfer

1998 • 43 citations

Tissue-specific Expression of the Gene for Type I Procollagen (COL1A1) in Transgenic Mice

1995 • 35 citations

Tissue- and development-specific expression in transgenic mice of a type I procollagen (COL1A1) minigene construct with 2.3 kb of the promoter region and 2 kb of the 3'-flanking region. Specificity is independent of the putative regulatory sequences in the first intron

1993 • 35 citations

Donor origin of the in vitro hematopoietic microenvironment after marrow transplantation in mice

1984 • 32 citations

Host origin of bone marrow fibroblasts following allogeneic bone marrow transplantation for chronic myeloid leukemia.

1992 • 31 citations

Evaluation of mixed chimaerism and origin of bone marrow derived fibroblastoid cells after allogeneic bone marrow transplantation

1994 • 30 citations

Origin of marrow stromal cells and haemopoietic chimaerism following bone marrow transplantation determined by in situ hybridisation

1990 • 27 citations

Structure and Helical Stability of a Modified Procollagen Synthesized in the Presence of 3,4-Dehydroproline

1982 • 20 citations

ERYTHROPOIETIN-DEPENDENT DIFFERENCES OF ERYTHROPOIETIC AMPLIFICATION BETWEEN MARROW AND SPLEEN

1991 • 5 citations