Dwl4(DRBl*0404) is a Dw4‐dependent risk factor for rheumatoid arthritis Rethinking the “shared epitope” hypothesis

Epidemiologic Research: Principles and Quantitative Methods.

1983 • 1,935 citations

Binding of immunogenic peptides to Ia histocompatibility molecules

1985 • 1,209 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

HLA and Disease Associations

1985 • 893 citations

Molecular diversity of HLA-DR4 haplotypes.

1986 • 385 citations

HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region.

1989 • 376 citations

HLA Genes associated with rheumatoid Arthritis. Identification of susceptibility alleles using specific oligonucleotide probes

1989 • 345 citations

DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression.

1985 • 340 citations

Activation of human T lymphocyte subsets: helper and suppressor/cytotoxic T cells recognize and respond to distinct histocompatibility antigens.

1981 • 338 citations

Onset, Early Stages, and Prognosis of Rheumatoid Arthritis: A Clinical Study of 100 Patients with 11-year Follow-up

1973 • 284 citations

Sequence polymorphism of HLA DRβ1 alleles relating to T-cell-recognized determinants

1985 • 183 citations

Association of HLA-Aw31 and HLA-DR1 with adult rheumatoid arthritis.

1982 • 168 citations

IDENTIFICATION OF HLA-Dw14 GENES IN DR4+ RHEUMATOID ARTHRITIS

1986 • 150 citations

Increased Frequency of HLA‐Cw3 and HLA‐Dw4 in Rheumatoid Arthritis

1977 • 149 citations

Association between HLA and Japanese patients with rheumatoid arthritis

1982 • 138 citations

Electrophoretic analysis of human HLA-DR antigens from HLA-DR4 homozygous cell lines: correlation between beta-chain diversity and HLA-D.

1983 • 133 citations

Association of HLA‐DR4/Dw4 and DR2/Dw2 with radiologic changes in a prospective study of patients with rheumatoid arthritis

1984 • 132 citations

Specific HLA-DR4-associated histocompatibility molecules characterize patients with seropositive juvenile rheumatoid arthritis.

1984 • 130 citations

Ten HLA-DR4 alleles defined by sequence polymorphisms within the DRB1 first domain

1991 • 110 citations

HLA and rheumatoid arthritis: a combined analysis of 440 British patients.

1986 • 110 citations

Hla‐dr alleles with naturally occurring amino acid substitutions and risk for development of rheumatoid arthritis

1990 • 103 citations

HLA—Dw4 and Rheumatoid Arthritis

1979 • 79 citations

Rheumatoid arthritis may be primarily associated with HLA‐DR4 molecules sharing a particular sequence at residues 67–74

1990 • 59 citations

HLA antigen associations with extra‐articular rheumatoid arthritis

1984 • 58 citations

Dw subtypes of DR4 in rheumatoid arthritis: Evidence for a preferential association with Dw4

1986 • 53 citations

Association of different HLA antigens with various toxic effects of gold salts in rheumatoid arthritis.

1986 • 50 citations

Autoimmune diseases and HLA.

1990 • 48 citations

HLA-Dw4 in adult and juvenile rheumatoid arthritis

2001 • 45 citations

Immunogenetics of rheumatoid arthritis in Israel

1986 • 41 citations

HLA Dr Antigens in Rheumatoid Arthritis

1983 • 40 citations

HLA-D and DR determinants in rheumatoid arthritis.

1979 • 40 citations

Class ii major histocompatibility complex gene sequences in rheumatoid arthritis. The third diversity regions of both DRβ₁ genes in two DR1, DRw10–positive individuals specify the same inferred amino acid sequence as the DRβ₁ and DRβ₂ Genes of a DR4 (Dw14) haplotype

1989 • 38 citations

HLA‐DR4 associated Dw types in rheumatoid arthritis

1989 • 30 citations

HLA‐DP in rheumatoid arthritis

1988 • 28 citations

HLA‐DR antigens in rheumatoid arthritis in North India

1982 • 21 citations

Clinical and immunogenetic studies in rheumatoid arthritis from northern India

1983 • 18 citations

Immune responses in an untransfused patient with aplastic anemia: Analysis of cytolytic and proliferative T cell clones

1984 • 17 citations

HLA-DR antigens in rheumatoid arthritis

1986 • 16 citations

Adult rheumatoid arthritis is associated with MC1, a new HLA-D encoded determinant.

1988 • 8 citations