Class ii major histocompatibility complex gene sequences in rheumatoid arthritis. The third diversity regions of both DRβ₁ genes in two DR1, DRw10–positive individuals specify the same inferred amino acid sequence as the DRβ₁ and DRβ₂ Genes of a DR4 (Dw14) haplotype

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

1987 • 2,539 citations

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

Association of the B-Cell Alloantigen DRw4 with Rheumatoid Arthritis

1978 • 1,170 citations

Molecular diversity of HLA-DR4 haplotypes.

1986 • 385 citations

Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes.

1987 • 351 citations

DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression.

1985 • 340 citations

Structure, Sequence and Polymorphism in the HLA‐D Region

1985 • 302 citations

Polymorphism of human Ia antigens: gene conversion between two DR β loci results in a new HLA-D/DR specificity

1986 • 292 citations

Genetic Complexity and Expression of Human Class II Histocompatibility Antigens

1985 • 247 citations

Mutations and selection in the generation of class II histocompatibility antigen polymorphism.

1984 • 232 citations

A Newly Characterized HLA DQ _β Allele Associated with Pemphigus Vulgaris

1988 • 230 citations

Allelic variation in the DR subregion of the human major histocompatibility complex.

1987 • 220 citations

Structural organization of the DR subregion of the human major histocompatibility complex.

1985 • 173 citations

IDENTIFICATION OF HLA-Dw14 GENES IN DR4+ RHEUMATOID ARTHRITIS

1986 • 150 citations

Association between HLA and Japanese patients with rheumatoid arthritis

1982 • 138 citations

DR antigens and rheumatoid arthritis: a study of two populations.

1981 • 128 citations

Gene conversion between murine class II major histocompatibility complex loci. Functional and molecular evidence from the bm 12 mutant.

1984 • 126 citations

DNA sequence and characterization of human class II major histocompatibility complex beta chains from the DR1 haplotype.

1985 • 109 citations

Mutation at I-A beta chain prevents experimental autoimmune myasthenia gravis

1985 • 106 citations

Polymorphism of HLA-DR beta chains in DR4, -7, and -9 haplotypes: implications for the mechanisms of allelic variation.

1986 • 79 citations

Molecular localization of human class II MT2 and MT3 determinants.

1984 • 72 citations

The molecular basis of susceptibility to rheumatoid arthritis: The conformational equivalence hypothesis

1988 • 60 citations

Nucleotide sequence of a DRw10 beta chain cDNA clone. Identity of the third D region with that of the DRw53 allele of the beta 2 locus and as the probable site encoding a polymorphic MHC class II epitope.

1988 • 55 citations

Dw subtypes of DR4 in rheumatoid arthritis: Evidence for a preferential association with Dw4

1986 • 53 citations

Characterization of two distinct DR beta chain alleles at the beta III locus of the DR5 haplotype: beta III alleles are highly conserved.

1986 • 44 citations

Molecular characterization of MT3 antigens by two-dimensional gel electrophoresis, NH2-terminal amino acid sequence analysis, and southern blot analysis.

1985 • 42 citations

Immunofluorescent Studies on Antibodies Directed to a Buried Membrane Structure Present in Lymphocytes and Erythrocytes

1975 • 39 citations

Strong association of rheumatoid arthritis with the presence of a polymorphic Ia epitope defined by a monoclonal antibody: comparison with the allodeterminant DR4

1984 • 36 citations

Structural relationships between the DR beta 1 and DR beta 2 subunits in DR4, 7, and w9 haplotypes and the DRw53 (MT3) specificity.

1986 • 36 citations

Association of certain Ia allotypes with the occurrence of chronic lymphocytic leukemia. Recognition by a monoclonal anti-Ia reagent of a susceptibility determinant not in the DR series

1982 • 34 citations

Evidence for the separate molecular expression of four distinct polymorphic Ia epitopes on cells of DR4 homozygous individuals

1984 • 30 citations

Definition of a possible genetic basis for susceptibility to acute myelogenous leukemia associated with the presence of a polymorphic Ia epitope.

1985 • 26 citations

Identification of the DRw10 DR beta 1-chain allele as encoding a polymorphic class II major histocompatibility complex epitope otherwise restricted to DR beta 2 molecules of the DRw53 type.

1988 • 22 citations