Structure of the Rat Catechol-O-Methyltransferase Gene: Separate Promoters Are Used to Produce mRNAs for Soluble and Membrane-Bound Forms of the Enzyme

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase

1982 • 1,539 citations

Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure

1979 • 1,403 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Enzymatic O-Methylation of Epinephrine and Other Catechols

1958 • 1,291 citations

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA

1991 • 1,019 citations

Compilation of vertebrate-encoded transcription factors

1992 • 934 citations

Large surface proteins of hepatitis B virus containing the pre-s sequence

1984 • 812 citations

Human CCAAT-binding proteins have heterologous subunits

1988 • 712 citations

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1984 • 561 citations

Catechol-O-methyl transferase: pharmacological aspects and physiological role.

1975 • 547 citations

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

1990 • 484 citations

Genomic organization of the human catechol O‐methyltransferase gene and its expression from two distinct promoters

1994 • 332 citations

Metal-regulated transcription in eukaryotes

1992 • 297 citations

Subcellular fate of the lnt-2 oncoprotein is determined by choice of initiation codon

1990 • 293 citations

Interactions Between Estrogens and Catechol Amines III. Studies on the Methylation of Catechol Estrogens, Catechol Amines and other Catechols by the Catechol-O-Methyltransferase1 of Human Liver

1972 • 282 citations

Human catechol-O-methyltransferase: cloning and expression of the membrane-associated form.

1991 • 197 citations

Operator constitutive mutation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter abolishes protein binding to sterol regulatory element.

1988 • 194 citations

Cloning and Characterization of Human Placental Catechol--Methyltransferase cDNA

1991 • 166 citations

The promoter, transcriptional unit, and coding sequence of herpes simplex virus 1 family 35 proteins are contained within and in frame with the UL26 open reading frame

1991 • 152 citations

Contribution of Sulfate Conjugation, Deamination, and O‐Methylation to Metabolism of Dopamine and Norepinephrine in Human Brain

1982 • 134 citations

Gene regulation by steroid hormones

1987 • 134 citations

A dictionary of transcription control sequences

1990 • 124 citations

Brain-specific genes have identifier sequences in their introns.

1984 • 120 citations

Molecular cloning and characterization of rat liver catechol-O-methyltransferase

1990 • 118 citations

New selective COMT inhibitors: useful adjuncts for Parkinson's disease?

1989 • 118 citations

Distinct Cellular Localization of Membrane‐Bound and Soluble Forms of Catechol‐O‐Methyltransferase in Brain

1983 • 111 citations

Kinetic studies on the O-methylation of dopamine by human brain membrane-bound catechol O-methyltransferase

1982 • 95 citations

Characterization of Membrane‐Bound and Soluble Catechol‐O‐Methyltransferase from Human Frontal Cortex

1984 • 95 citations

Regulation of a bifunctional mRNA results in synthesis of secreted and nuclear probasin.

1989 • 83 citations

Soluble and Particulate Forms of Rat Catechol-O-Methyltransferase Distinguished by Gel Electrophoresis and Immune Fixation

1985 • 70 citations

The transcription factor LF-A1 interacts with a bipartite recognition sequence in the promoter regions of several liver-specific genes

1991 • 68 citations

Identification of proteins interacting with the enhancer of human U2 small nuclear RNA genes

1987 • 68 citations

Expression of recombinant soluble and membrane‐bound catechol O‐methyltransferase in eukaryotic cells and identification of the respective enzymes in rat brain

1992 • 48 citations

MAO, COMT, and GABA‐T Activities in Primary Astroglial Cultures

1983 • 46 citations

Cell‐free synthesis of rat and human catechol O‐methyltransferase

1991 • 41 citations

Purification and partial characterization of rat liver soluble catechol‐ O‐methyltransferase

1990 • 40 citations

Presence of membrane-bound catechol-o-methyltransferase in human brain

1980 • 38 citations

Catechol-o-methyl-transferase activity in dibutyryl cyclic AMP, prostaglandin and X-ray -induced differentiated neuroblastoma cell culture

1972 • 32 citations

METABOLISM OF BIOGENIC AMINES IN NEUROBLASTOMA AND GLIOMA CELLS IN CULTURE¹

1976 • 28 citations

Purification and partial sequence analysis of the soluble catechol-o-methyltransferase from human placenta: Comparison to the rat liver enzyme

1991 • 28 citations

CONCOMITANT ELEVATION OF TYROSINE HYDROXYLASE AND DOPAMINE BETA‐HYDROXYLASE BY CYCLIC AMP IN CULTURED MOUSE NEUROBLASTOMA CELLS¹

1978 • 21 citations

Characterization of Three Distinct Size Classes of Human 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase mRNA: Expression of the Transcripts in Hepatic and Nonhepatic Cells

1990 • 15 citations

Synthesis of long cDNA from viral RNA template

1988 • 7 citations