An amino-terminal extension is required for the secretion of chick agrin and its binding to extracellular matrix.

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1987 • 834 citations

Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

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Multiple domains of the large fibroblast proteoglycan, versican.

1989 • 646 citations

Polymerase Chain Reaction with Single-Sided Specificity: Analysis of T Cell Receptor δ Chain

1989 • 640 citations

The Agrin Hypothesis

1990 • 637 citations

Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis

1994 • 541 citations

Protein Translocation Across Membranes

1988 • 482 citations

Identification of agrin, a synaptic organizing protein from Torpedo electric organ.

1987 • 467 citations

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Structure and expression of a rat agrin

1991 • 310 citations

The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans

1993 • 305 citations

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1995 • 281 citations

Agrin induces phosphorylation of the nicotinic acetylcholine receptor

1991 • 253 citations

The agrin gene codes for a family of basal lamina proteins that differ in function and distribution

1992 • 252 citations

Identification and synthesis of a recognition signal for the attachment of glycosaminoglycans to proteins.

1987 • 251 citations

Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site.

1995 • 232 citations

Agrin released by motor neurons induces the aggregation of acetylcholine receptors at neuromuscular junctions

1992 • 231 citations

RNA splicing regulates agrin-mediated acetylcholine receptor clustering activity on cultured myotubes

1992 • 212 citations

cDNA that encodes active agrin

1992 • 199 citations

DM-GRASP, a novel immunoglobulin superfamily axonal surface protein that supports neurite extension

1991 • 192 citations

Developmental regulation of highly active alternatively spliced forms of agrin

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The Role of Agrin in Synapse Formation

1995 • 181 citations

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1987 • 177 citations

Proteoglycans of basement membranes

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1989 • 163 citations

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1986 • 157 citations

The regulation of synaptogenesis during normal development and following activity blockade

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1988 • 130 citations

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Functions of agrin and agrin-related proteins

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Structure and chromosomal localization of the mammalian agrin gene

1992 • 115 citations

Agrin mediates cell contact-induced acetylcholine receptor clustering

1991 • 113 citations

Staurosporine inhibits agrin-induced acetylcholine receptor phosphorylation and aggregation.

1994 • 104 citations

Agrin-related molecules are concentrated at acetylcholine receptor clusters in normal and aneural developing muscle.

1989 • 104 citations

A widely distributed antigen developmentally regulated in the nervous system

1990 • 104 citations

Building synapses: agrin and dystroglycan stick together

1994 • 100 citations

Survival in vitro of motoneurons identified or purified by novel antibodybased methods is selectively enhanced by muscle-derived factors

1991 • 99 citations

Localization and alternative splicing of agrin mRNA in adult rat brain: transcripts encoding isoforms that aggregate acetylcholine receptors are not restricted to cholinergic regions

1994 • 98 citations

A homologue of the axonally secreted protein axonin-1 is an integral membrane protein of nerve fiber tracts involved in neurite fasciculation.

1989 • 80 citations

Early appearance of and neuronal contribution to agrin-like molecules at embryonic frog nerve-muscle synapses formed in culture

1992 • 77 citations

Cell-specific regulation of agrin RNA splicing in the chick ciliary ganglion

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Basal lamina components are concentrated in premuscle masses and at early acetylcholine receptor clusters in chick embryo hindlimb muscles

1988 • 71 citations

A heparan sulfate proteoglycan in developing avian axonal tracts

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1988 • 68 citations

Distribution of alpha-dystroglycan during embryonic nerve-muscle synaptogenesis.

1995 • 68 citations

Distribution of agrin mRNAs in the chick embryo nervous system

1994 • 65 citations

Analysis of proteoglycan expression in developing chicken brain: Characterization of a heparan sulfate proteoglycan that interacts with the neural cell adhesion molecule

1995 • 64 citations

Comparison of agrin-like proteins from the extracellular matrix of chicken kidney and muscle with neural agrin, a synapse organizing protein

1991 • 60 citations

A muscle cell variant defective in glycosaminoglycan biosynthesis forms nerve-induced but not spontaneous clusters of the acetylcholine receptor and the 43 kDa protein

1993 • 57 citations

Identification of a Novel Alternatively Spliced Agrin mRNA That Is Preferentially Expressed in Non-neuronal Cells

1995 • 51 citations

Developmental Expression and Alternative Splicing of Chick Agrin RNA

1993 • 48 citations

Muscle-derived agrin in cultured myotubes: Expression in the basal lamina and at induced acetylcholine receptor clusters

1992 • 47 citations

Immunochemical and biochemical evidence for distinct basement membrane heparan sulfate proteoglycans.

1993 • 36 citations

Agrin mRNA variants are differentially regulated in developing chick embryo spinal cord and sensory ganglia

1995 • 34 citations

Neuritic deposition of agrin on culture substrate: implications for nerve-muscle synaptogenesis

1994 • 33 citations

Chapter 13 Analysis of Protein Topology in the Endoplasmic Reticulum

1991 • 24 citations

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