Relaxin Alone and in Conjunction with Interferon-γ Decreases Collagen Synthesis by Cultured Human Scleroderma Fibroblasts

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Preliminary criteria for the classification of systemic sclerosis (scleroderma)

1980 • 4,703 citations

Expression of human immune interferon cDNA in E. coli and monkey cells

1982 • 703 citations

The estimation of two collagens from human dermis by interrupted gel electrophoresis

1976 • 564 citations

Increased Collagen Synthesis by Scleroderma Skin Fibroblasts In Vitro A POSSIBLE DEFECT IN THE REGULATION OR ACTIVATION OF THE SCLERODERMA FIBROBLAST

1974 • 545 citations

Selective inhibition of human diploid fibroblast collagen synthesis by interferons.

1984 • 336 citations

Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts.

1990 • 320 citations

The progeny of rabbit articular chondrocytes synthesize collagen types I and III and type I trimer, but not type II. Verifications by cyanogen bromide peptide analysis

1977 • 319 citations

Reorganization of polymerized actin: a possible trigger for induction of procollagenase in fibroblasts cultured in and on collagen gels.

1986 • 256 citations

Scleroderma

1979 • 241 citations

Variability in Collagen and Fibronectin Synthesis by Scleroderma Fibroblasts in Primary Culture

1981 • 201 citations

Gamma-interferon inhibits collagen synthesis in vivo in the mouse.

1987 • 181 citations

Tumor necrosis factor-alpha and interferon-gamma suppress the activation of human type I collagen gene expression by transforming growth factor-beta 1. Evidence for two distinct mechanisms of inhibition at the transcriptional and posttranscriptional levels.

1990 • 178 citations

A Controlled Trial of Intralesional Recombinant Interferon-? in the Treatment of Keloidal Scarring

1990 • 165 citations

Failure of substrate-induced gluconeogenesis to increase overall glucose appearance in normal humans. Demonstration of hepatic autoregulation without a change in plasma glucose concentration.

1990 • 162 citations

Influences of gamma interferon on synovial fibroblast-like cells. Ia induction and inhibition of collagen synthesis.

1985 • 134 citations

Double‐blind trial of recombinant γ‐interferon versus placebo in the treatment of rheumatoid arthritis

1989 • 110 citations

Inhibition of excessive scleroderma fibroblast collagen production by recombinant γ‐interferon: Association with a coordinate decrease in types I and III procollagen messenger RNA levels

1986 • 106 citations

ANTRAL-GASTRIN-CELL HYPERPLASIA IN PEPTIC ULCER DISEASE

1974 • 96 citations

The Systemic Administration of Gamma Interferon Inhibits Collagen Synthesis and Acute Inflammation in a Murine Skin Wounding Model

1989 • 94 citations

Cyclic AMP response to recombinant human relaxin by cultured human endometrial cells—A specific and high throughput in vitro bioassay

1990 • 94 citations

Ameliorating effect of murine interferon gamma on bleomycin-induced lung collagen fibrosis in mice

1986 • 88 citations

Effects of interferon-gamma on expression of cell surface receptors for collagen and deposition of newly synthesized collagen by cultured human lung fibroblasts.

1989 • 81 citations

RADIOIMMUNOASSAY OF RELAXIN IN PREGNANCY WITH AN ANALOGUE OF HUMAN RELAXIN

1986 • 77 citations

USE OF RELAXIN IN THE TREATMENT OF SCLERODERMA

1958 • 73 citations

Progressive systemic sclerosis (PSS, scleroderma) dermal fibroblasts synthesize increased amounts of glycosaminoglycan.

1983 • 71 citations

Scleroderma (Systemic Sclerosis)

2011 • 10 citations