Pharmacologic and Therapeutic Differences Among Calcium Channel Antagonists: Profile of Mibefradil, a New Calcium Antagonist

Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone

1990 • 1,098 citations

Classes of Calcium Channels in Vertebrate Cells

1989 • 1,082 citations

Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.

1984 • 553 citations

Antiarrhythmic Agents: The Modulated Receptor Mechanism of Action of Sodium and Calcium Channel-Blocking Drugs

1984 • 544 citations

Molecular Basis for CA2+ Channel Diversity

1994 • 461 citations

Selective inhibition of T-type Ca2+ channels by Ro 40-5967.

1994 • 367 citations

Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.

1983 • 292 citations

Calcium antagonism in heart and smooth muscle

1984 • 258 citations

Calcium antagonism in heart and smooth muscle: Experimental facts and therapeutic prospects

1983 • 207 citations

Molecular determinants of Ca2+ channel function and drug action

1995 • 198 citations

Molecular biology of calcium channels

1995 • 182 citations

PDGF and TGF-β mediate collagen production by mesangial cells exposed to advanced glycosylation end products

1995 • 175 citations

Identification of a phenylalkylamine binding region within the alpha 1 subunit of skeletal muscle Ca2+ channels.

1990 • 171 citations

The angiotensin AT₂ receptor modulates T‐type calcium current in non‐differentiated NG108‐15 cells

1992 • 130 citations

Subunit-dependent modulation of recombinant L-type calcium channels. Molecular basis for dihydropyridine tissue selectivity.

1993 • 128 citations

Mibefradil Prevents Neointima Formation After Vascular Injury in Rats

1995 • 120 citations

Comparison of location and binding for the positively charged 1,4-dihydropyridine calcium channel antagonist amlodipine with uncharged drugs of this class in cardiac membranes.

1989 • 117 citations

Diagnosis and Treatment of Senile Dementia

1989 • 114 citations

Classification of calcium antagonists

1987 • 110 citations

In Vitro Pharmacologic Profile of Ro 40-5967, a Novel Ca2+ Channel Blocker with Potent Vasodilator but Weak Inotropic Action

1989 • 102 citations

Ro 40–5967: A New Nondihydropyridine Calcium Antagonist

1991 • 97 citations

Calcium channel diversity in the cardiovascular system

1996 • 93 citations

In Vitro Pharmacologic Profile of Ro 40-5967, a Novel Ca2+ Channel Blocker with Potent Vasodilator but Weak Inotropic Action

1989 • 85 citations

Lack of Negative Inotropic Effects of the New Calcium Antagonist Ro 40–5967 in Patients with Stable Angina Pectoris

1991 • 80 citations

Selectivity Scale of Calcium Antagonists in the Human Cardiovascular System Based on In Vitro Studies

1992 • 78 citations

Effects of Ro 40-5967, a Novel Calcium Antagonist, on Myocardial Function During Ischemia Induced by Lowering Coronary Perfusion Pressure in Dogs: Comparison with Verapamil

1989 • 74 citations

Calcium antagonists and vasodilation

1994 • 73 citations

Drug- and disease-induced regulation of voltage-dependent calcium channels.

1990 • 72 citations

Calcium-channel antagonists: mechanisms of action, vascular selectivities, and clinical relevance

1992 • 65 citations

Characterization of ion channels seen in subconfluent human dermal fibroblasts.

1991 • 63 citations

The binding interactions of Ro 40-5967 at the L-type Ca2+ channel in cardiac tissue

1995 • 61 citations

Calcium channel antagonists: cardiovascular selectivity of action.

1995 • 55 citations

Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol

1993 • 50 citations

Calcium Antagonists Should Continue to Be Used for First-Line Treatment of Hypertension

1995 • 50 citations

Potential-dependent inhibition of cardiac Ca2+ inward currents by Ro 40-5967 and verapamil: relation to negative inotropy

1991 • 46 citations

Effects of calcium channel blockade on the aortic intima in spontaneously hypertensive rats.

1993 • 38 citations

Calcium channel antagonists part II: Use and comparative properties of the three prototypical calcium antagonists in ischemic heart disease, including recommendations based on an analysis of 41 trials

1988 • 35 citations

Cardiovascular Profile of Ro 40–5967, a New Nondihydropyridine Calcium Antagonist, Delineated in Isolated, Blood-Perfused Dog Hearts

1993 • 33 citations

Transfer of Nimodipine and Another Calcium Antagonist Across the Blood-Brain Barrier and Their Regional Distribution In Vivo

1989 • 19 citations

Molecular and cellular mechanisms of antiarrhythmic agents

1991 • 13 citations

Calcium channel antagonists part V: Second-generation agents

1988 • 12 citations

Benzothiazepinone Binding Domain of Purified L-Type Calcium Channels: Direct Labeling Using a Novel Fluorescent Diltiazem Analog

1995 • 10 citations