Seizures, not hippocampal neuronal death, provoke neurogenesis in a mouse rapid electrical amygdala kindling model of seizures

The Mouse Brain in Stereotaxic Coordinates

2001 • 12,804 citations

Modification of seizure activity by electrical stimulation: II. Motor seizure

1972 • 6,939 citations

Neurogenesis in the adult human hippocampus

1998 • 6,181 citations

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

1996 • 3,079 citations

A permanent change in brain function resulting from daily electrical stimulation

1969 • 3,056 citations

Functional neurogenesis in the adult hippocampus

2002 • 2,813 citations

Neuronal replacement from endogenous precursors in the adult brain after stroke

2002 • 2,731 citations

Dentate Granule Cell Neurogenesis Is Increased by Seizures and Contributes to Aberrant Network Reorganization in the Adult Rat Hippocampus

1997 • 1,880 citations

Is the underlying cause of epilepsy a major prognostic factor for recurrence?

1998 • 1,038 citations

Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration

1997 • 994 citations

Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice

2002 • 954 citations

Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures

1997 • 789 citations

Continuation of neurogenesis in the hippocampus of the adult macaque monkey

1999 • 765 citations

Excitation-Neurogenesis Coupling in Adult Neural Stem/Progenitor Cells

2004 • 656 citations

Altered patterns of dynorphin immunoreactivity suggest mossy fiber reorganization in human hippocampal epilepsy

1990 • 615 citations

Long‐Term Effects of Pilocarpine in Rats: Structural Damage of the Brain Triggers Kindling and Spontaneous I Recurrent Seizures

1991 • 614 citations

Granule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsy

1990 • 604 citations

Granule-Like Neurons at the Hilar/CA3 Border after Status Epilepticus and Their Synchrony with Area CA3 Pyramidal Cells: Functional Implications of Seizure-Induced Neurogenesis

2000 • 598 citations

Genetic determinants of susceptibility to excitotoxic cell death: Implications for gene targeting approaches

1997 • 523 citations

Pathophysiological Mechanisms of Brain Damage from Status Epilepticus

1993 • 478 citations

Patterns of Status Epilepticus-Induced Neuronal Injury during Development and Long-Term Consequences

1998 • 416 citations

Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model

2003 • 390 citations

Adult‐born hippocampal neurons mature into activity‐dependent responsiveness

2003 • 322 citations

MRI-negative PET-positive temporal lobe epilepsy: a distinct surgically remediable syndrome

2004 • 314 citations

Neurogenesis in the Dentate Gyrus of the Rat Following Electroconvulsive Shock Seizures

2000 • 298 citations

Kindling-induced neurogenesis in the dentate gyrus of the rat

1998 • 264 citations

Increased dentate granule cell neurogenesis following amygdala kindling in the adult rat

1998 • 261 citations

Inciting Excitotoxic Cytocide Among Central Neurons

1986 • 231 citations

Apoptosis and necrosis induced in different hippocampal neuron populations by repetitive perforant path stimulation in the rat

1996 • 227 citations

Immunohistochemical Evidence of Seizure-Induced Activation of trk Receptors in the Mossy Fiber Pathway of Adult Rat Hippocampus

1999 • 189 citations

Kindling with rapidly recurring hippocampal seizures

1985 • 182 citations

Continuous cytosine‐b‐D‐arabinofuranoside infusion reduces ectopic granule cells in adult rat hippocampus with attenuation of spontaneous recurrent seizures following pilocarpine‐induced status epilepticus

2004 • 171 citations

Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- or kainate-induced status epilepticus

2000 • 158 citations

Steroid hormones affect limbic afterdischarge thresholds and kindling rates in adult female rats

1999 • 146 citations

Neuronal Cell Death in a Rat Model for Mesial Temporal Lobe Epilepsy Is Induced by the Initial Status Epilepticus and Not by Later Repeated Spontaneous Seizures

2003 • 144 citations

Time course of degenerative alterations in nigral dopaminergic neurons following a 6-hydroxydopamine lesion

2000 • 137 citations

Null Mutation of c-fosImpairs Structural and Functional Plasticities in the Kindling Model of Epilepsy

1996 • 135 citations

The hippocampus in experimental chronic epilepsy: A morphometric analysis

1990 • 125 citations

Acidosis Induces Necrosis and Apoptosis of Cultured Hippocampal Neurons

2000 • 121 citations

Morphological changes in the dentate gyrus in human temporal lobe epilepsy.

1992 • 114 citations

Characterizing cortical neuron injury with fluoro-jade labeling after a neurotoxic regimen of methamphetamine

1998 • 114 citations

Amygdala-kindled and pentylenetetrazole-induced seizures in glutamate transporter GLAST-deficient mice

1999 • 111 citations

Serum neuron-specific enolase is a marker for neuronal damage following status epilepticus in the rat

1997 • 111 citations

Higher Seizure Susceptibility and Enhanced Tyrosine Phosphorylation of N-Methyl-d-Aspartate Receptor Subunit 2B in fyn Transgenic Mice

1998 • 89 citations

Granule cell dispersion in relation to mossy fiber sprouting, hippocampal cell loss, silent period and seizure frequency in the pilocarpine model of epilepsy.

1992 • 88 citations

Hippocampal cell proliferation and epileptogenesis after audiogenic kindling are not accompanied by mossy fiber sprouting or fluoro-jade staining

2003 • 87 citations

Immunohistochemical Evidence of Seizure-Induced Activation of trkB Receptors in the Mossy Fiber Pathway of Adult Mouse Hippocampus

2002 • 79 citations

Seizure-induced neuronal death is associated with induction of c-Jun N-terminal kinase and is dependent on genetic background

2000 • 74 citations

Blockade of neuropsin, a serine protease, ameliorates kindling epilepsy

1998 • 71 citations

Dentate granule cell neurogenesis after seizures induced by pentylenetrazol in rats

2003 • 64 citations

The impact of genetic background on neurodegeneration and behavior in seizured mice

2004 • 60 citations

Granule cell disorganization in the dentate gyrus: possible alterations of neuronal migration in human temporal lobe epilepsy.

1992 • 57 citations

Role of AMPA and GluR5 kainate receptors in the development and expression of amygdala kindling in the mouse

2001 • 57 citations

Kindling induces neuropsin mRNA in the mouse brain

1996 • 57 citations

Enhanced epileptogenesis in S100B knockout mice

2002 • 56 citations

Suppressed Kindling Epileptogenesis and Perturbed BDNF and TrkB Gene Regulation in NT-3 Mutant Mice

1997 • 55 citations

Amygdala kindling develops without mossy fiber sprouting and hippocampal neuronal degeneration in rats

2001 • 49 citations

Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor α2

2000 • 49 citations

Pattern of neuronal loss in the rat hippocampus following experimental cardiac arrest-induced ischemia

1999 • 48 citations

Antiepileptic effects of topiramate on amygdaloid kindling in rats

1998 • 43 citations

Rapid kindling in the prepubescent rat

1987 • 35 citations

Increased mitotic activity in the dentate gyrus of the hippocampus of adult C57BL/6J mice exposed to the flurothyl kindling model of epileptogenesis

2002 • 32 citations

Dendritic aberrations in the hippocampal granular layer and the amygdalohippocampal area following kindled-seizures

2001 • 28 citations

LU 73068, a new non‐NMDA and glycine/NMDA receptor antagonist: pharmacological characterization and comparison with NBQX and L‐701,324 in the kindling model of epilepsy

1998 • 28 citations

Suppression of epileptogenesis by modification of N‐methyl‐<scp>d</scp>‐aspartate receptor subunit composition

1999 • 28 citations

Genes differentially expressed in the kindled mouse brain

2001 • 28 citations

Kindling and associated mossy fibre sprouting are not affected in mice deficient of NGFI-AINGFI-B genes

1998 • 26 citations

The Treatment of Epilepsy

1994 • 24 citations

Effect of depth electrode implantation with or without subsequent kindling on GABA turnover in various rat brain regions

1999 • 23 citations

Differential expression of mRNAs for sialyltransferase isoenzymes induced in the hippocampus of mouse following kindled seizures

2001 • 14 citations

Effects of an every other day rapid kindling procedure in prenatally protein malnourished rats

1995 • 7 citations