Regulation of a Calcium-dependent Tyrosine Kinase in Vascular Smooth Muscle Cells by Angiotensin II and Platelet-derived Growth Factor

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

1992 • 1,456 citations

Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions

1995 • 1,367 citations

Autophosphorylation of the Focal Adhesion Kinase, ppl25^FAK, Directs SH2-Dependent Binding of pp60^src

1994 • 1,168 citations

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1996 • 971 citations

Platelet-derived growth factor receptor signals.

1994 • 561 citations

Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation.

1994 • 414 citations

Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

1995 • 385 citations

Identification and Characterization of a Novel Related Adhesion Focal Tyrosine Kinase (RAFTK) from Megakaryocytes and Brain

1995 • 365 citations

Activation of Pyk2 by Stress Signals and Coupling with JNK Signaling Pathway

1996 • 310 citations

Identification of an Essential Signaling Cascade for Mitogen-activated Protein Kinase Activation by Angiotensin II in Cultured Rat Vascular Smooth Muscle Cells

1996 • 263 citations

Activation of a Novel Calcium-dependent Protein-tyrosine Kinase

1996 • 256 citations

The Related Adhesion Focal Tyrosine Kinase Is Tyrosine-phosphorylated after β1-Integrin Stimulation in B Cells and Binds to p130cas

1997 • 214 citations

Angiotensin II stimulates the pp44 and pp42 mitogen-activated protein kinases in cultured rat aortic smooth muscle cells

1992 • 210 citations

Platelet‐derived Growth Factor

1995 • 200 citations

Acute hypertension activates mitogen-activated protein kinases in arterial wall.

1996 • 200 citations

Angiotensin II Activates pp60 ^{c- src} in Vascular Smooth Muscle Cells

1995 • 167 citations

Characterization of RAFTK, a novel focal adhesion kinase, and its integrin-dependent phosphorylation and activation in megakaryocytes

1996 • 167 citations

The Related Adhesion Focal Tyrosine Kinase Forms a Complex with Paxillin in Hematopoietic Cells

1996 • 142 citations

Focal adhesion kinase is abundant in developing blood vessels and elevation of its phosphotyrosine content in vascular smooth muscle cells is a rapid response to angiotensin II

1994 • 122 citations

Paxillin Is Tyrosine-phosphorylated by and Preferentially Associates with the Calcium-dependent Tyrosine Kinase in Rat Liver Epithelial Cells

1997 • 118 citations

Differential Effects of Platelet-derived Growth Factor BB on p125 Focal Adhesion Kinase and Paxillin Tyrosine Phosphorylation and on Cell Migration in Rabbit Aortic Vascular Smooth Muscle Cells and Swiss 3T3 Fibroblasts

1995 • 113 citations

Role of p70 S6 Protein Kinase in Angiotensin II-induced Protein Synthesis in Vascular Smooth Muscle Cells

1995 • 105 citations

Regulation of cell proliferation and growth by angiotensin II

1994 • 100 citations

Angiotensin II stimulation of rapid paxillin tyrosine phosphorylation correlates with the formation of focal adhesions in rat aortic smooth muscle cells

1995 • 97 citations

Tyrosine Phosphorylation of the Related Adhesion Focal Tyrosine Kinase in Megakaryocytes upon Stem Cell Factor and Phorbol Myristate Acetate Stimulation and Its Association with Paxillin

1997 • 96 citations

Focal adhesion kinase: Structure and signalling

1994 • 96 citations

Angiotensin II Stimulates Tyrosine Phosphorylation of the Focal Adhesion-associated Protein Paxillin in Aortic Smooth Muscle Cells

1995 • 94 citations

Ca<sup>2+</sup> Homeostasis in Vascular Smooth Muscle

1995 • 83 citations

An Intracellular Calcium Signal Activates p70 but Not p90 Ribosomal S6 Kinase in Liver Epithelial Cells

1997 • 79 citations

Tyrosine Phosphorylation of the Novel Protein-tyrosine Kinase RAFTK during an Early Phase of Platelet Activation by an Integrin Glycoprotein IIb-IIIa-independent Mechanism

1997 • 78 citations

Angiotensin II Activates at Least Two Tyrosine Kinases in Rat Liver Epithelial Cells

1995 • 69 citations

Platelet‐derived growth factor and angiotensin II cause increases in cytosolic free calcium by different mechanisms in vascular smooth muscle cells

1989 • 53 citations

Molecular Cloning and Assignment of FAK2, a Novel Human Focal Adhesion Kinase, to 8p11.2–p22 by Nonisotopicin SituHybridization

1996 • 51 citations

Platelet-derived growth factor (PDGF) alpha receptor activation modulates the calcium mobilizing activity of the PDGF beta receptor in Balb/c3T3 fibroblasts.

1992 • 42 citations

The role of tyrosine phosphorylation in angiotensin II-mediated intracellular signalling

1995 • 41 citations

Pathophysiology of smooth muscle in hypertension

1995 • 34 citations

Role of the tissue renin-angiotensin system in vascular remodeling and smooth muscle cell growth

1994 • 33 citations

Angiotensin II Mediates Intracellular Signaling in Vascular Smooth Muscle Cells by Activation of Tyrosine-Specific Protein Kinases and c-raf-1

1993 • 30 citations