Platelet‐derived growth factor and angiotensin II cause increases in cytosolic free calcium by different mechanisms in vascular smooth muscle cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

The biology of platelet-derived growth factor

1986 • 2,036 citations

A Platelet-Dependent Serum Factor That Stimulates the Proliferation of Arterial Smooth Muscle Cells In Vitro

1974 • 1,838 citations

The GTP-binding protein, Go9 regulates neuronal calcium channels

1987 • 910 citations

Calcium-mobilizing receptors, polyphosphoinositides, and the generation of second messengers.

1986 • 831 citations

Two Classes of PDGF Receptor Eecognize Different Isoforms of PDGF

1988 • 603 citations

A G Protein Directly Regulates Mammalian Cardiac Calcium Channels

1987 • 551 citations

Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes

1987 • 533 citations

Inositol trisphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor

1984 • 520 citations

Early changes in phosphatidylinositol and arachidonic acid metabolism in quiescent swiss 3T3 cells stimulated to divide by platelet-derived growth factor.

1981 • 492 citations

Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells.

1986 • 491 citations

Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C

1985 • 476 citations

Vasoconstriction: A New Activity for Platelet-Derived Growth Factor

1986 • 430 citations

Growth factors immediately raise cytoplasmic free Ca2+ in human fibroblasts.

1984 • 394 citations

Platelet‐derived growth factor is a chemoattractant for vascular smooth muscle cells

1982 • 340 citations

Increase in cytosolic calcium and phosphoinositide metabolism induced by angiotensin II and [Arg]vasopressin in vascular smooth muscle cells.

1985 • 252 citations

Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death.

1989 • 252 citations

Inhibition by islet-activating protein of a chemotactic peptide-induced early breakdown of inositol phospholipids and Ca2+ mobilization in guinea pig neutrophils.

1985 • 250 citations

Guanine nucleotide-binding protein Go-induced coupling of neuropeptide Y receptors to Ca2+ channels in sensory neurons.

1988 • 242 citations

Pathways of Ca2+ influx at the plasma membrane: Voltage-, receptor-, and second messenger-operated channels

1987 • 223 citations

Epidermal growth factor stimulates the rapid accumulation of inositol (1,4,5)-trisphosphate and a rise in cytosolic calcium mobilized from intracellular stores in A431 cells.

1987 • 202 citations

Insulin-like growth factor II stimulates calcium influx in competent BALB/c 3T3 cells primed with epidermal growth factor. Characteristics of calcium influx and involvement of GTP-binding protein.

1987 • 192 citations

Cytosolic free calcium levels in monolayers of cultured rat aortic smooth muscle cells. Effects of angiotensin II and vasopressin.

1985 • 175 citations

Epidermal growth factor and angiotensin II stimulate formation of inositol 1,4,5- and inositol 1,3,4-trisphosphate in hepatocytes. Differential inhibition by pertussis toxin and phorbol 12-myristate 13-acetate.

1987 • 168 citations

Calcium-activated hydrolysis of phosphatidyl-myo-inositol 4-phosphate and phosphatidyl-myo-inositol 4,5-bisphosphate in guinea-pig synaptosomes

1978 • 167 citations

Angiotensin II rapidly increases phosphatidate-phosphoinositide synthesis and phosphoinositide hydrolysis and mobilizes intracellular calcium in cultured arterial muscle cells.

1984 • 159 citations

Induction of protein kinase C activation and Ca²⁺ mobilization by fibroblast growth factor in Swiss 3T3 cells

1985 • 148 citations

Angiotensin II induces expression of the - gene through protein kinase C activation and calcium ion mobilization in cultured vascular smooth muscle cells

1988 • 146 citations

Early agonist-mediated ionic events in cultured vascular smooth muscle cells. Calcium mobilization is associated with intracellular acidification.

1987 • 145 citations

Inhibitory effect of calcium antagonists on balloon catheter-induced arterial smooth muscle cell proliferation and lesion size

1988 • 127 citations

Requirement for calcium ions in acetylcholine-stimulated phosphodiesteratic cleavage of phosphatidyl-myo-inositol 4,5-bisphosphate in rabbit iris smooth muscle

1980 • 122 citations

Early changes in inositol lipids and their metabolites induced by platelet-derived growth factor in quiescent Swiss mouse 3T3 cells

1985 • 114 citations

Pharmacology of Calcium Channels and Smooth Muscle

1986 • 100 citations

Carbachol causes rapid phosphodiesteratic cleavage of phosphatidylinositol 4,5-bisphosphate and accumulation of inositol phosphates in rabbit iris smooth muscle; prazosin inhibits noradrenaline- and ionophore A23187-stimulated accumulation of inositol phosphates

1984 • 97 citations

Receptor occupancy dose—response curve suggests that phosphatidyl‐inositol breakdown may be intrinsic to the mechanism of the muscarinic cholinergic receptor

1976 • 92 citations

Vasopressin induced production of inositol trisphosphate and calcium efflux in a smooth muscle cell line

1985 • 91 citations

Formation and actions of calcium-mobilizing messenger, inositol 1,4,5-trisphosphate

1987 • 65 citations

Aequorin detects increased cytoplasmic calcium in platelets stimulated with phorbol ester or diacylglycerol

1985 • 64 citations

Diacylglycerol increases cytosolic free Ca2+ concentration in rat pituitary cells. Relationship to thyrotropin-releasing hormone action.

1987 • 54 citations

Calcium Antagonists as Antiatherogenic Agents

1988 • 51 citations

Antiproliferative action of protein kinase C in cultured rabbit aortic smooth muscle cells

1987 • 51 citations

Platelet‐derived growth factor stimulates rapid polyphosphoinositide breakdown in fetal human fibroblasts

1985 • 48 citations

The relationship between phosphatidylinositol metabolism and mobilization of intracellular calcium elicited by alpha1-adrenergic receptor stimulation in BC3H-1 muscle cells.

1984 • 40 citations

Platelet‐derived growth factor‐induced alterations in vinculin distribution in porcine vascular smooth muscle cells

1987 • 37 citations

The Effect of Calcium Antagonists on Intimal Cell Proliferation in Atherogenesis^a

1988 • 37 citations

Activation of calcium mobilization and calcium influx by alpha1-adrenergic receptors in a smooth muscle cell line

1985 • 36 citations

Effects of platelet-derived growth factor on Ca2+ in 3T3 cells

1985 • 27 citations

Interaction of phorbol esters with Ca²⁺ channels in smooth muscle

1987 • 26 citations

Alterations of excitation-contraction coupling by platelet-derived growth factor in enzymatically isolated and cultured vascular smooth muscle cells

1985 • 22 citations

Mobilization of intracellular calcium by alpha 1-adrenergic receptor activation in muscle cell monolayers.

1986 • 21 citations

Platelet‐activating factor mobilises intracellular calcium in vascular smooth muscle cells

1986 • 19 citations

Effects of Calcium-Antagonists and Calmodulin Inhibitors on DNA Synthesis in Cultured Rat Vascular Smooth Muscle Cells

1987 • 18 citations

Intracellular free calcium transients induced by norepinephrine in rat aortic smooth muscle cells in primary culture

1986 • 16 citations

Beta adrenergic regulation of glycogen phosphorylase activity and adenosine cyclic 3', 5'-monophosphate accumulation in control and desensitized C-6 astrocytoma cells.

1977 • 16 citations

Influence of a tumor-promoting phorbol ester on the electrical response of B-cells to glucose and glyburide.

1984 • 12 citations

Pathways of second messenger generation by PDGF in vascular smooth muscle cells

1987 • 1 citations