Structurally and catalytically important residues in the phosphate binding loop of adenylate kinase of Escherichia coli

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Calcium-dependent bacteriophage DNA infection

1970 • 2,743 citations

pEMBL: a new family of single stranded plasmids

1983 • 1,231 citations

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

1989 • 881 citations

The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA

1985 • 849 citations

Structure of the GDP Domain of EF-Tu and Location of the Amino Acids Homologous to ras Oncogene Proteins

1985 • 626 citations

Biological properties of human c-Ha-ras1 genes mutated at codon 12

1984 • 586 citations

Three-Dimensional Structure of an Oncogene Protein: Catalytic Domain of Human c-H- ras P21

1988 • 532 citations

P1,P5-Di(adenosine-5′)pentaphosphate, a Potent Multisubstrate Inhibitor of Adenylate Kinase

1973 • 524 citations

Blue dextran-sepharose: an affinity column for the dinucleotide fold in proteins.

1975 • 425 citations

Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography.

1985 • 396 citations

Genetically Determined Variation of Adenylate Kinase in Man

1966 • 363 citations

Purification of ras GTPase activating protein from bovine brain.

1988 • 255 citations

Spectrophotometric determination of protein concentration in cell extracts containing tRNA's and rRNA's

1973 • 250 citations

[12] Systems for polyacrylamide gel electrophoresis

1984 • 208 citations

Synthetic Inhibitors of Adenylate Kinases in the Assays for ATPases and Phosphokinases

1975 • 180 citations

Über Invertseifen, VIII. Mitteil.: Reduktion von Tetrazoliumsalzen durch Bakterien, gärende Hefe und keimende Samen

1941 • 163 citations

Binding of Cibacron blue F3GA to proteins containing the dinucleotide fold.

1976 • 158 citations

Reconstruction by site-directed mutagenesis of the transition state for the activation of tyrosine by the tyrosyl-tRNA synthetase: a mobile loop envelopes the transition state in an induced-fit mechanism

1988 • 158 citations

Effect of single amino acid replacements on the thermal stability of the NH2-terminal domain of phage lambda repressor.

1984 • 153 citations

Two conformations of crystalline adenylate kinase

1977 • 146 citations

The glycine‐rich loop of adenylate kinase forms a giant anion hole

1986 • 143 citations

Structure of the complex of yeast adenylate kinase with the inhibitor P1,P5-di(adenosine-5′-)pentaphosphate at 2.6 Å resolution

1987 • 131 citations

Use of binding energy in catalysis analyzed by mutagenesis of the tyrosyl-tRNA synthetase

1986 • 116 citations

Mutations in the nucleotide binding loop of adenylate kinase of Escherichia coli

1988 • 114 citations

Structural and catalytic characteristics of Escherichia coli adenylate kinase.

1987 • 81 citations

Structure of the complex of adenylate kinase from Escherichia coli with the inhibitor P1,P5-di(adenosine-5′-)pentaphosphate

1988 • 70 citations

Simple and fast purification of Escherichia coli adenylate kinase

1983 • 63 citations

Affinity labeling of adenylate kinase with adenosine diphosphopyridoxal. Presence of Lys21 in the ATP-binding site.

1987 • 62 citations

A reactive arginine in adenylate kinase

1975 • 62 citations

Site-directed alterations in the ATP-binding domain of rho protein affect its activities as a termination factor.

1988 • 61 citations

Directed mutagenesis of the strongly conserved lysine 175 in the proposed nucleotide-binding domain of alpha-subunit from Escherichia coli F1-ATPase.

1988 • 58 citations

Spectral changes induced in Cibacron Blue F3GA by salts, organic solvents, and polypeptides: Implications for Blue dye interaction with proteins

1982 • 57 citations

The switch between two conformations of adenylate kinase

1988 • 49 citations

cDNA-derived sequence of UMP-CMP kinase from Dictyostelium discoideum and expression of the enzyme in Escherichia coli.

1990 • 41 citations

Adenylate kinases from thermosensitive Escherichia coli strains

1989 • 39 citations

Optimized conditions for solid-phase sequencing: simultaneous chemical cleavage of a series of long DNA fragments immobilized on CCS anion-exchange paper

1986 • 28 citations

Proton-nuclear magnetic resonance studies of the aromatic spin systems of Escherichia coli adenylate kinase

1988 • 6 citations

A general method for visualizing enzymes releasing adenosine or adenosine-5?-monophosphate

1984 • 2 citations