Blockade of ?2-adrenoceptors increases opioid ?-receptor-mediated inhibition of the firing rate of rat locus coeruleus neurones

Endogenous opioid peptides: multiple agonists and receptors

1977 • 2,494 citations

Nucleus locus ceruleus: new evidence of anatomical and physiological specificity

1983 • 1,877 citations

Presynaptic regulation of the release of catecholamines.

1980 • 1,483 citations

Regulation of noradrenaline release by presynaptic receptor systems

1977 • 1,482 citations

Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal.

1980 • 836 citations

The Classification of Adrenoceptors (Adrenergic Receptors). An Evaluation from the Standpoint of Receptor Theory

1972 • 812 citations

CLASSIFICATION OF OPIOID RECEPTORS

1983 • 787 citations

Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization

1977 • 712 citations

Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

1987 • 616 citations

α ₂ -Adrenoceptor-Mediated Hyperpolarization of Locus Coeruleus Neurons: Intracellular Studies in Vivo

1982 • 427 citations

SELECTIVITY OF BLOCKING AGENTS FOR PRE‐ AND POSTSYNAPTIC α‐ADRENOCEPTORS

1977 • 424 citations

Studies on RX 781094: a selective, potent and specific antagonist of α₂‐adrenoceptors

1983 • 357 citations

Pre- and postsynaptic effects of yohimbine stereoisomers on noradrenergic transmission in the pulmonary artery of the rabbit

1979 • 273 citations

On the potassium conductance increased by opioids in rat locus coeruleus neurones.

1985 • 265 citations

Enkephalin opens potassium channels on mammalian central neurones

1982 • 264 citations

Characterization of α2-adrenoceptors which increase potassium conductance in rat locus coeruleus neurones

1985 • 246 citations

Pertussis toxin blocks the outward currents evoked by opiate and α2-agonists in locus coeruleus neurons

1986 • 241 citations

Noradrenaline‐mediated synaptic inhibition in rat locus coeruleus neurones.

1983 • 202 citations

Common α2- and opiate effector mechanisms in the locus coeruleus: intracellular studies in brain slices

1987 • 202 citations

Inward rectification of resting and opiate-activated potassium currents in rat locus coeruleus neurons

1988 • 169 citations

Opiate-receptor interactions on single locus coeruleus neurones.

1984 • 166 citations

Relative potencies of alpha-1 and alpha-2 antagonists in the locus ceruleus, dorsal raphe and dorsal lateral geniculate nuclei: an electrophysiological study.

1982 • 155 citations

Mechanisms of receptor-mediated modulation of transmitter release in noradrenergic, cholinergic and sensory neurones

1986 • 108 citations

Interaction between neuropeptide Y and noradrenaline on central catecholamine neurons

1990 • 92 citations

Modulation of transmitter and hormone release by multiple neuronal opioid receptors

2005 • 89 citations

Electrophysiological properties of neurones contained in the locus coeruleus and mesencephalic nucleus of the trigeminal nerve in vitro

1982 • 83 citations

Presynaptic ?2-adrenoceptor, opioid ?-receptor and adenosine A1-receptor interactions on noradrenaline release in rabbit brain cortex

1988 • 74 citations

Characterization of Opioid Receptors Modulating Noradrenaline Release in the Hippocampus of the Rabbit

1986 • 69 citations

Blockade of ?2-adrenoceptors permits the operation of otherwise silent opioid ?-receptors at the sympathetic axons of rabbit jejunal arteries

1986 • 61 citations

Opioid receptor sub-types involved in the control of transmitter release in cortex of the brain of the rat

1984 • 60 citations

Presynaptic K‐Opioid Receptors on Noradrenergic Nerve Terminals Couple to G Proteins and Interact with the α₂‐Adrenoceptors

1989 • 56 citations

Mutual interaction between presynaptic ? 2-adrenoceptors and opioid ?-receptors at the noradrenergic axons of rabbit brain cortex

1986 • 56 citations

Activation of presynaptic ?2-adrenoceptors attenuates the inhibitory effect of ?-opioid receptor agonists on noradrenaline release from brain slices

1986 • 46 citations

Inhibitory synaptic potentials recorded from mammalian neurones prolonged by blockade of noradrenaline uptake.

1987 • 43 citations

Receptors on individual neurones

1986 • 37 citations

Effects of pertussis toxin on opioid regulation of catecholamine release from rat and guinea pig brain slices

1989 • 27 citations

Effects of purinoceptor agonists on electrophysiological properties of rat mesencephalic trigeminal neurones in vitro

1988 • 26 citations

Only activated but not non-activated presynaptic ?2-autoreceptors interfere with neighbouring presynaptic receptor mechanisms

1988 • 24 citations

Receptor Interactions at Noradrenergic Neur ones^a

1990 • 12 citations