Endogenous opioid peptides: multiple agonists and receptors
Data up to Jan 2025
Total Citations Per Year
Abstract
References (26)
Identification of two related pentapeptides from the brain with potent opiate agonist activity
1975 • 3,780 citations
The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.
1976 • 2,883 citations
Opiate Receptor: Demonstration in Nervous Tissue
1973 • 2,364 citations
Opiates and endogenous opioid peptides
1977 • 1,282 citations
Stereospecific Binding of the Potent Narcotic Analgesic [ 3 H]Etorphine to Rat-Brain Homogenate
1973 • 1,055 citations
Immunohistochemical studies using antibodies to leucine-enkephalin: Initial observations on the nervous system of the rat
1976 • 767 citations
Choline esters in tissue extracts
1933 • 490 citations
C fragment of lipotropin has a high affinity for brain opiate receptors
1976 • 488 citations
The effects of morphine and nalorphine-like drugs in the nondependent, morphine-dependent and cyclazocine-dependent chronic spinal dog.
1976 • 467 citations
[D-Ala 2 ]-Met-Enkephalinamide: A Potent, Long-Lasting Synthetic Pentapeptide Analgesic
1976 • 466 citations
Characteristics of the “Receptor” for Narcotic Analgesics in Synaptic Plasma Membrane Fraction from Rat Brain
1973 • 426 citations
EFFECT OF MORPHINE ON ADRENERGIC TRANSMISSION IN THE MOUSE VAS DEFERENS. ASSESSMENT OF AGONIST AND ANTAGONIST POTENCIES OF NARCOTIC ANALGESICS
1975 • 406 citations
The effects of adrenaline, noradrenaline and isoprenaline on inhibitory α‐ and β‐adrenoceptors in the longitudinal muscle of the guinea‐pig ileum
1970 • 360 citations
In Vitro Models in the Study of Structure-Activity Relationships of Narcotic Analgesics
1975 • 289 citations
Endorphins are located in the intermediate and anterior lobes of the pituitary gland, not in the neurohypophysis
1977 • 273 citations
Some thoughts on the significance of enkephalin, the endogenous ligand
1975 • 270 citations
Opioid activity of a peptide, beta-lipotropin-(61-91), derived from beta-lipotropin.
1976 • 264 citations
Isolation, primary structure, and synthesis of α-endorphin and γ-endorphin, two peptides of hypothalamic-hypophysial origin with morphinomimetic activity
1976 • 216 citations
A New Concept on the Mode of Interaction of Narcotic Analgesics with Receptors
1965 • 207 citations
beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins.
1976 • 206 citations
Receptor binding and pharmacological activity of opiates in the guinea-pig intestine.
1975 • 182 citations
ASSESSMENT IN THE GUINEA‐PIG ILEUM AND MOUSE VAS DEFERENS OF BENZOMORPHANS WHICH HAVE STRONG ANTINOCICEPTIVE ACTIVITY BUT DO NOT SUBSTITUTE FOR MORPHINE IN THE DEPENDENT MONKEY
1975 • 177 citations
Comparative study on analgesic effect of Met5-enkephalin and related lipotropin fragments
1976 • 146 citations
Stereospecific increase by narcotic antagonists of evoked acetylcholine output in guinea-pig ileum
1975 • 101 citations
Contribution of ‘receptor’ affinity to analgesic potency
1974 • 37 citations
Comparison between Narcotic “Receptors” in the Guinea‐pig Ileum and the Rat Brain
1975 • 32 citations