Smoking withdrawal, nicotine dependence and prepulse inhibition of the acoustic startle reflex

Measuring degree of physical dependence to tobacco smoking with reference to individualization of treatment

1978 • 2,231 citations

Measuring nicotine dependence: A review of the Fagerstrom Tolerance Questionnaire

1989 • 1,569 citations

Prestimulus Effects on Human Startle Reflex in Normals and Schizophrenics

1978 • 1,173 citations

Gating and Habituation of the Startle Reflex in Schizophrenic Patients

1992 • 1,030 citations

Assessing the Validity of an Animal Model of Deficient Sensorimotor Gating in Schizophrenic Patients

1994 • 702 citations

The neural substrates of sensorimotor gating of the startle reflex: a review of recent findings and their implications

1992 • 394 citations

A preliminary assessment of sensorimotor gating in patients with obsessive compulsive disorder

1993 • 355 citations

Startle gating deficits occur across prepulse intensities in schizophrenic patients

1992 • 332 citations

Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder

1993 • 310 citations

Cholinergic neurons in the pedunculopontine tegmental nucleus are involved in the mediation of prepulse inhibition of the acoustic startle response in the rat

1993 • 271 citations

Examination of drug-induced and isolation-induced disruptions of prepulse inhibition as models to screen antipsychotic drugs

1995 • 231 citations

Baseline startle amplitude and prepulse inhibition in Vietnam veterans with posttraumatic stress disorder

1996 • 221 citations

Clozapine and haloperidol in an animal model of sensorimotor gating deficits in schizophrenia

1993 • 189 citations

Multiple serotonin receptor subtypes modulate prepulse inhibition of the startle response in rats

1994 • 179 citations

Sensorimotor gating and habituation evoked by electro-cutaneous stimulation in schizophrenia

1994 • 149 citations

Effect of cigarette smoking on prepulse inhibition of the acoustic startle reflex in healthy male smokers

1996 • 124 citations

Nicotine increases sensory gating measured as inhibition of the acoustic startle reflex in rats

1994 • 116 citations

DOI disruption of prepulse inhibition of startle in the rat is mediated by 5-HT2A and not by 5-HT2C receptors

1995 • 115 citations

8-OH-DPAT disruption of prepulse inhibition in rats: reversal with (+)WAY 100,135 and localization of site of action

1995 • 100 citations

The effects of haloperidol and clozapine on the disruption of sensorimotor gating induced by the noncompetitive glutamate antagonist MK-801

1993 • 99 citations

Effect of acute subcutaneous nicotine on prepulse inhibition of the acoustic startle reflex in healthy male non-smokers

1997 • 97 citations

Nicotine withdrawal: a behavioral assessment using schedule controlled responding, locomotor activity, and sensorimotor reactivity

1993 • 82 citations

A relationship between inhibition of the acoustic startle response and the protection of prepulse processing

1996 • 80 citations

Nocotine dependence in cigarette smoking: An empirically-based, multivariate model

1983 • 80 citations

Effect of nicotine, lobeline, and mecamylamine on sensory gating in the rat

1994 • 78 citations

D1 and D2 dopamine receptor antagonists reverse prepulse inhibition deficits in an animal model of schizophrenia

1994 • 70 citations

Ventral pallidal GABA-A receptors regulate prepulse inhibition of acoustic startle

1995 • 59 citations

Prepulse inhibition of the acoustic startle reflex using visual and auditory prepulses: disruption by apomorphine

1995 • 58 citations

Cholinergic mechanisms in startle and prepulse inhibition: Effects of the false cholinergic precursor N-aminodeanol.

1993 • 41 citations

Habituation and prepulse inhibition of the acoustic startle reflex: Effects of smoking status and psychosis-proneness

1997 • 32 citations

Alterations in Other Sensory Modalities Accompanying Stress Analgesia as Measured by Startle Reflex Modification^a

1986 • 21 citations