Nicotine increases sensory gating measured as inhibition of the acoustic startle reflex in rats

Statistical principles in experimental design.

1962 • 27,228 citations

Statistical Principles in Experimental Design

1964 • 8,376 citations

Neuropsychopharmacology

1990 • 1,545 citations

Prestimulus Effects on Human Startle Reflex in Normals and Schizophrenics

1978 • 1,173 citations

Basic and clinical pharmacology

1988 • 1,173 citations

THE PHARMACOLOGICAL BASIS OF THERAPEUTICS

1967 • 1,039 citations

Gating and Habituation of the Startle Reflex in Schizophrenic Patients

1992 • 1,030 citations

Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats

1986 • 693 citations

Dopaminergic stimulation disrupts sensorimotor gating in the rat

1988 • 609 citations

Autoradiographic evidence for nicotine receptors on nigrostriatal and mesolimbic dopaminergic neurons

1985 • 527 citations

Effects of acute subcutaneous nicotine on attention, information processing and short-term memory in alzheimer's disease

1992 • 478 citations

Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics

1992 • 417 citations

Nicotinic effects on the firing pattern of midbrain dopamine neurons

1986 • 399 citations

Effects of phencyclidine and phencyclidine biologs on sensorimotor gating in the rat*1

1989 • 375 citations

Effects of scopolamine and nicotine on human rapid information processing performance

1984 • 350 citations

Central dopamine hyperactivity in rats mimics abnormal acoustic startle response in schizophrenics

1986 • 341 citations

Intravenous nicotine in Alzheimer's disease: a pilot study

1988 • 312 citations

Preferential stimulation of ventral tegmental area dopaminergic neurons by nicotine

1987 • 275 citations

Autoradiographic distribution of nicotine receptors in rat brain

1984 • 253 citations

Stimulation of nigrostriatal dopamine neurones by nicotine

1982 • 232 citations

Stereoselective Nicotine‐Induced Release of Dopamine from Striatal Synaptosomes: Concentration Dependence and Repetitive Stimulation

1988 • 209 citations

Failure of haloperidol to block the effects of phencyclidine and dizocilpine on prepulse inhibition of startle

1991 • 189 citations

Effects of Nicotine on Stimulus Sensitivity and Response Bias in a Visual Vigilance Task

1983 • 171 citations

Electrophysiological actions of nicotine on substantia nigra single units

1985 • 169 citations

Apomorphine disrupts the inhibition of acoustic startle induced by weak prepulses in rats

1990 • 141 citations

A D2 dopamine receptor agonist disrupts sensorimotor gating in rats. Implications for dopaminergic abnormalities in schizophrenia.

1990 • 138 citations

Autoradiographic distribution of high affinity muscarinic and nicotinic cholinergic receptors labeled with [3H]acetylcholine in rat brain

1986 • 101 citations

Startle-inducing acoustic stimuli evoke ultrasonic vocalization in the rat

1990 • 95 citations

Effects of d- and l-amphetamine on habituation and sensitization of the acoustic startle response in rats

1975 • 85 citations

Differential effects of apomorphine on prepulse inhibition of acoustic startle reflex in two rat strains

1990 • 85 citations

A comparison of the attentional and consolidation hypotheses for the facilitation of memory by nicotine

1992 • 71 citations

Effects of nicotine on the acoustic startle reflex amplitude in rats

1991 • 69 citations

Facilitation of memory by post-trial administration of nicotine: evidence for an attentional explanation

1992 • 68 citations

Apomorphine, d-amphetamine, strychnine and yohimbine do not alter prepulse inhibition of the acoustic startle reflex

1988 • 64 citations

Effects of mecamylamine on avoidance conditioning and maze learning of mice.

1966 • 61 citations

Radial-arm maze performance in rats is impaired by a combination of nicotinic-cholinergic and D2 dopaminergic antagonist drugs

1989 • 59 citations

Effect of Amphetamine, Nicotine and Hexamethonium on Performance of a Conditioned Response During Acquisition and Retention Trials

1970 • 57 citations

Reversal of a mecamylamine-induced cognitive deficit with the D2 agonist, LY 171555

1989 • 54 citations

Studies on the mechanism of avoidance facilitation by nicotine

1971 • 44 citations

Involvement of norepinephrine in startle arousal after acute and chronic d-amphetamine administration

1978 • 38 citations

Analysis of behavioral effects of drugs

1990 • 30 citations

Nicotine-produced relearning deficit in C57BL/6J and DBA/2J mice

1985 • 29 citations

Comparative cognition and assessment of cognitive processes in animals

1992 • 21 citations

Cholinergic Mechanisms and Avoidance Behavior Acquisition: Effects of Nicotine in Mice

1971 • 19 citations