The Neurospora Checkpoint Kinase 2: A Regulatory Link Between the Circadian and Cell Cycles

Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints

2004 • 3,161 citations

The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

2002 • 2,045 citations

The genome sequence of the filamentous fungus Neurospora crassa

2003 • 1,660 citations

Linkage of ATM to Cell Cycle Regulation by the Chk2 Protein Kinase

1998 • 1,314 citations

DNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2

2000 • 1,269 citations

The Circadian Gene Period2 Plays an Important Role in Tumor Suppression and DNA Damage Response In Vivo

2002 • 1,216 citations

Time zones: a comparative genetics of circadian clocks

2001 • 1,142 citations

Control Mechanism of the Circadian Clock for Timing of Cell Division in Vivo

2003 • 1,101 citations

A high-throughput gene knockout procedure for Neurospora reveals functions for multiple transcription factors

2006 • 1,070 citations

The ATM–Chk2–Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

2001 • 1,051 citations

Chk2/hCds1 functions as a DNA damage checkpoint in G₁by stabilizing p53

2000 • 781 citations

A Suppressor of Two Essential Checkpoint Genes Identifies a Novel Protein that Negatively Affects dNTP Pools

1998 • 733 citations

A Web of Circadian Pacemakers

2002 • 732 citations

The Circadian Gene Per1 Plays an Important Role in Cell Growth and DNA Damage Control in Human Cancer Cells

2006 • 579 citations

Increased Breast Cancer Risk among Women Who Work Predominantly at Night

2001 • 497 citations

Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway

1998 • 453 citations

Chk2 kinase — a busy messenger

2001 • 396 citations

Interconnected Feedback Loops in the Neurospora Circadian System

2000 • 352 citations

Alternative Initiation of Translation and Time-Specific Phosphorylation Yield Multiple Forms of the Essential Clock Protein FREQUENCY

1997 • 346 citations

The PAS Protein VIVID Defines a Clock-Associated Feedback Loop that Represses Light Input, Modulates Gating, and Regulates Clock Resetting

2001 • 318 citations

Coupling of Human Circadian and Cell Cycles by the Timeless Protein

2005 • 283 citations

The Chk2 protein kinase

2004 • 239 citations

Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock

2000 • 203 citations

The Neurospora Circadian System

2004 • 201 citations

Clock Genes in Cell Clocks: Roles, Actions, and Mysteries

2004 • 156 citations

Temperature Compensation of Circadian Period Length in Clock Mutants of Neurospora crassa

1981 • 124 citations

Circadian variation of cell proliferation and cell cycle protein expression in man: Clinical implications

2000 • 102 citations

Reduced expression and impaired kinase activity of a Chk2 mutant identified in human lung cancer.

2001 • 58 citations

The Circadian Clock and Tumor Suppression by Mammalian Period Genes

2005 • 49 citations

Effect of constant light on DMBA mammary tumorigenesis in rats

2000 • 45 citations

Tumor chronobiology

2001 • 22 citations

Timing the cell cycle

2003 • 21 citations

The cyclin-dependent kinase (cdk) inhibitors, olomoucine and roscovitine, alter the expression of a molluscan circadian pacemaker.

1997 • 20 citations

Molecular Analysis of the Neurospora Clock: Cloning and Characterization of the frequency and period-4 Genes

1992 • 8 citations