Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma.

Germinal Centers

1994 • 1,680 citations

Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections.

1993 • 691 citations

BCL-6 protein is expressed in germinal-center B cells

1995 • 582 citations

Microsatellite instability: marker of a mutator phenotype in cancer.

1994 • 552 citations

LAZ3, a novel zinc–finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas

1993 • 444 citations

The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins.

1995 • 393 citations

Establishment and characterization of an Epstein-Barr virus (EBC)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African Burkitt's lymphoma.

1975 • 390 citations

Rearrangement of the bcl-6 Gene as a Prognostic Marker in Diffuse Large-Cell Lymphoma

1994 • 387 citations

Antibody diversity: Somatic hypermutation of rearranged VH genes

1981 • 334 citations

LAZ3 rearrangements in non-Hodgkin's lymphoma: correlation with histology, immunophenotype, karyotype, and clinical outcome in 217 patients

1994 • 316 citations

Rearrangements of the BCL6 gene in diffuse large cell non-Hodgkin's lymphoma

1994 • 302 citations

Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma

1983 • 286 citations

Stable Expression and Somatic Hypermutation of Antibody V Regions in B-Cell Developmental Pathways

1989 • 271 citations

Cloning of bcl-6, the locus involved in chromosome translocations affecting band 3q27 in B-cell lymphoma.

1993 • 254 citations

Analysis of RAS oncogene mutations in human lymphoid malignancies.

1988 • 226 citations

Targeting of non-lg sequences in place of the V segment by somatic hyper mutation

1995 • 223 citations

Discriminating intrinsic and actigen-selected mutational hotspots in immunoglobulin V genes

1993 • 222 citations

Deletions involving two distinct regions of 6q in B-cell non-Hodgkin lymphoma

1992 • 182 citations

Gene involved in the 3q27 translocation associated with B-cell lymphoma, BCL5, encodes a Kruppel-like zinc-finger protein

1994 • 144 citations

Origins of human cancer: A comprehensive review

1992 • 139 citations

The presence of clonogenic cells in high-grade malignant lymphoma: a prognostic factor

1987 • 128 citations

Analysis of LAZ3 (BCL-6) status in B-cell non-Hodgkin's lymphomas: results of rearrangement and gene expression studies and a mutational analysis of coding region sequences

1995 • 124 citations

Clonal analysis of a human antibody response. II. Sequences of the VH genes of human IgM, IgG, and IgA to rabies virus reveal preferential utilization of VHIII segments and somatic hypermutation.

1993 • 100 citations

Frequent incidence of somatic mutations in translocated BCL2 oncogenes of non-Hodgkin's lymphomas

1992 • 98 citations

Somatic hypermutation in V-regions.

1991 • 75 citations

Structural analysis of the VH-D-JH segments of human polyreactive IgG mAb. Evidence for somatic selection.

1993 • 62 citations

BCL-6 and the Molecular Pathogenesis of B-Cell Lymphoma

1994 • 31 citations

Non-Hodgkin’s Lymphomas

1989 • 23 citations

The Molecular Genetics of Cancer

1995 • 20 citations