FTDP‐17 mutations N279K and S305N in tau produce increased splicing of exon 10

Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

1998 • 3,377 citations

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1989 • 2,308 citations

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

1998 • 1,440 citations

Tau is a candidate gene for chromosome 17 frontotemporal dementia

1998 • 1,344 citations

Tau proteins of alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms

1992 • 1,058 citations

Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.

1989 • 989 citations

Mutation-Specific Functional Impairments in Distinct Tau Isoforms of Hereditary FTDP-17

1998 • 954 citations

Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization.

1990 • 849 citations

Tau protein pathology in neurodegenerative diseases

1998 • 674 citations

Structure and novel exons of the human .tau. gene

1992 • 587 citations

Tau proteins with FTDP‐17 mutations have a reduced ability to promote microtubule assembly

1998 • 469 citations

Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17

1998 • 464 citations

Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17: A New Group of Tauopathies

1998 • 459 citations

The role of exon sequences in splice site selection.

1993 • 367 citations

Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau

1998 • 336 citations

Familial multiple system tauopathy with presenile dementia: A disease with abundant neuronal and glial tau filaments

1997 • 334 citations

A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding.

1993 • 300 citations

Tau Pathology in Two Dutch Families with Mutations in the Microtubule-Binding Region of Tau

1998 • 281 citations

Tau Mutations Cause Frontotemporal Dementias

1998 • 267 citations

Segregation of a Missense Mutation in the Microtubule-Associated Protein Tau Gene with Familial Frontotemporal Dementia and Parkinsonism

1998 • 236 citations

Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles

1996 • 157 citations

The Neuropathology of a Chromosome 17-Linked Autosomal Dominant Parkinsonism and Dementia (“Pallido-Ponto-Nigral Degeneration”)

1998 • 142 citations