Adult-Born Hippocampal Dentate Granule Cells Undergoing Maturation Modulate Learning and Memory in the Brain

Mammalian Neural Stem Cells

2000 • 4,689 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

2003 • 4,175 citations

More hippocampal neurons in adult mice living in an enriched environment

1997 • 3,476 citations

Mechanisms and Functional Implications of Adult Neurogenesis

2008 • 2,904 citations

Running enhances neurogenesis, learning, and long-term potentiation in mice

1999 • 2,829 citations

Neurogenesis in the adult is involved in the formation of trace memories

2001 • 2,014 citations

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

2009 • 1,563 citations

Pattern Separation in the Dentate Gyrus and CA3 of the Hippocampus

2007 • 1,550 citations

Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus

2004 • 1,256 citations

GABA regulates synaptic integration of newly generated neurons in the adult brain

2005 • 1,221 citations

Distinct Morphological Stages of Dentate Granule Neuron Maturation in the Adult Mouse Hippocampus

2006 • 1,193 citations

Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

2008 • 1,011 citations

Pattern Separation in the Human Hippocampal CA3 and Dentate Gyrus

2008 • 995 citations

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

2006 • 992 citations

GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain

2004 • 963 citations

Doublecortin expression levels in adult brain reflect neurogenesis

2005 • 942 citations

Dentate Gyrus NMDA Receptors Mediate Rapid Pattern Separation in the Hippocampal Network

2007 • 928 citations

A Critical Period for Enhanced Synaptic Plasticity in Newly Generated Neurons of the Adult Brain

2007 • 886 citations

Neurogenesis may relate to some but not all types of hippocampal‐dependent learning

2002 • 854 citations

Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus

2007 • 854 citations

A role for adult neurogenesis in spatial long-term memory

2004 • 830 citations

Neurons born in the adult dentate gyrus form functional synapses with target cells

2008 • 709 citations

Neural stem and progenitor cells in nestin‐GFP transgenic mice

2004 • 685 citations

Neuronal Differentiation in the Adult Hippocampus Recapitulates Embryonic Development

2005 • 646 citations

Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis

2003 • 638 citations

Potential role for adult neurogenesis in the encoding of time in new memories

2006 • 631 citations

Dissociating hippocampal subregions: A double dissociation between dentate gyrus and CA1

2001 • 630 citations

Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats

2009 • 620 citations

Rapid extension of axons into the CA3 region by adult-generated granule cells

1999 • 597 citations

NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus

2006 • 594 citations

A computational theory of hippocampal function, and empirical tests of the theory

2006 • 591 citations

Inhibition of neurogenesis interferes with hippocampus‐dependent memory function

2006 • 573 citations

Spatial Relational Memory Requires Hippocampal Adult Neurogenesis

2008 • 568 citations

Synapse formation on neurons born in the adult hippocampus

2007 • 550 citations

Aging Results in Reduced Epidermal Growth Factor Receptor Signaling, Diminished Olfactory Neurogenesis, and Deficits in Fine Olfactory Discrimination

2004 • 541 citations

A role for adult TLX-positive neural stem cells in learning and behaviour

2008 • 512 citations

Experience-Specific Functional Modification of the Dentate Gyrus through Adult Neurogenesis: A Critical Period during an Immature Stage

2007 • 505 citations

Importance of newly generated neurons in the adult olfactory bulb for odor discrimination

2000 • 484 citations

Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment

2006 • 449 citations

Visualization of neurogenesis in the central nervous system using nestin promoter-GFP transgenic mice

2000 • 379 citations

Computational Influence of Adult Neurogenesis on Memory Encoding

2009 • 364 citations

Context Fear Learning in the Absence of the Hippocampus

2006 • 350 citations

Nestin expression in hair follicle sheath progenitor cells

2003 • 348 citations

Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy

2000 • 281 citations

Hippocampal involvement in contextual modulation of fear extinction

2007 • 280 citations

What is the most sensitive measure of water maze probe test performance?

2009 • 203 citations

Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain

2008 • 196 citations

Traumatic Brain Injury-Induced Hippocampal Neurogenesis Requires Activation of Early Nestin-Expressing Progenitors

2008 • 176 citations

Different Requirements for Protein Synthesis in Acquisition and Extinction of Spatial Preferences and Context-Evoked Fear

2001 • 167 citations

Variant Brain-Derived Neurotrophic Factor (Val66Met) Alters Adult Olfactory Bulb Neurogenesis and Spontaneous Olfactory Discrimination

2008 • 159 citations

Hippocampal Mek/Erk signaling mediates extinction of contextual freezing behavior

2006 • 102 citations

Cultured Nestin–Positive Cells from Postnatal Mouse Small Bowel Differentiate Ex Vivo into Neurons, Glia, and Smooth Muscle

2004 • 92 citations

Impaired fear memory and decreased hippocampal neurogenesis following olfactory bulbectomy in rats

2005 • 70 citations

Conditional ablation and recovery of forebrain neurogenesis in the mouse

2009 • 65 citations

Olfactory bulbectomy temporarily impairs Morris maze performance: An ACTH(4?9) analog accellerates return of function

1995 • 61 citations