Rat NKR‐P1⁺ CD3⁺ T cells: selective proliferation in interleukin‐2, diverse T‐cell‐receptor‐Vβ repertoire and polarized interferon‐γ expression

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Functional diversity of helper T lymphocytes

1996 • 4,512 citations

Acquisition of Lymphokine-Producing Phenotype by CD4+ T Cells

1994 • 1,573 citations

Generation and Analysis of Interleukin-4 Deficient Mice

1991 • 1,266 citations

An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.

1994 • 1,044 citations

IL-12-Deficient Mice Are Defective in IFNγ Production and Type 1 Cytokine Responses

1996 • 991 citations

CD1 Recognition by Mouse NK1 ⁺ T Lymphocytes

1995 • 903 citations

CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.

1994 • 862 citations

Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice.

1993 • 612 citations

Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes.

1995 • 517 citations

Role of NK1.1 ⁺ T Cells in a T _H 2 Response and in Immunoglobulin E Production

1995 • 508 citations

Immunoglobulin E Production in the Absence of Interleukin-4-Secreting CD1-Dependent Cells

1997 • 501 citations

CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major.

1994 • 397 citations

NK1.1+ T cell receptor-alpha/beta+ cells: new clues to their origin, specificity, and function.

1995 • 355 citations

Dendritic cells and macrophages are required for Th1 development of CD4⁺ T cells from αβ TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-_γ production is IFN-_γ-dependent

1993 • 346 citations

Type 1 and Type 2: a fundamental dichotomy for all T-cell subsets

1996 • 320 citations

IL-4 Rapidly Produced by Vβ4 Vα8 CD4+ T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice

1997 • 315 citations

Mouse NK1+ T cells

1995 • 292 citations

An NK1.1+ CD4+8- single-positive thymocyte subpopulation that expresses a highly skewed T-cell antigen receptor V beta family.

1992 • 270 citations

Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells.

1996 • 268 citations

Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody.

1991 • 250 citations

Predominant expression of invariant V_α14⁺ TCR α chain in NK1.1⁺ T cell populations

1995 • 243 citations

Mouse NK1.1+ T cells: a new family of T cells

1996 • 236 citations

Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses.

1996 • 207 citations

The Th1/Th2 balance in autoimmunity

1995 • 198 citations

Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells.

1994 • 158 citations

Metal ion induced autoimmunity

1995 • 154 citations

Close phenotypic and functional similarities between human and murine alphabeta T cells expressing invariant TCR alpha-chains.

1997 • 135 citations

Characterization of the immune response to a secondary encephalitogenic epitope of basic protein in Lewis rats. II. Biased T cell receptor V beta expression predominates in spinal cord infiltrating T cells.

1992 • 94 citations

Early production of IL-4 and induction of Th2 responses in the lymph node originate from an MHC class I-independent CD4+NK1.1- T cell population.

1996 • 85 citations

In vivo induction of type 1 and 2 immune responses against protein antigens

1997 • 80 citations

Compounds that induce autoimmunity in the Brown Norway rat sensitize mast cells for mediator release and interleukin-4 expression

1995 • 73 citations

Interleukin‐4 Gene Expression in Mercury‐Induced Autoimmunity

1995 • 61 citations

Characterization and function of the NKR-P1dim/T cell receptor-alpha beta+ subset of rat T cells.

1994 • 44 citations

Experimental autoimmune encephalomyelitis in “low” and “high” interleukin 2 producer rats

1989 • 32 citations

The role of protein kinase C in CD8+ T lymphocyte effector responses.

1997 • 21 citations

Rat T cell response to superantigens. I. V beta-restricted clonal deletion of rat T cells differentiating in rat-->mouse chimeras.

1994 • 16 citations

Selection for susceptibility to experimental allergic encephalomyelitis also selects for high IFN-gamma production.

1995 • 15 citations

Restricted T cell receptor usage in DA rats during early collagen‐induced arthritis

1994 • 13 citations

Cloning, functional activities and in vivo tissue distribution of rat NKR-P1+ TCR alpha beta + cells

1997 • 12 citations

Phenotype Characteristics of NKR-P1+ Cells in Rats

1997 • 1 citations