Antiepileptic Drug Development: II. Anticonvulsant Drug Screening

A Note on a Simple Apparatus for Detecting Neurological Deficit in Rats and Mice**College of Pharmacy, University of Nebraska, Lincoln 8.

1957 • 1,671 citations

Comparative assays of antiepileptic drugs in mice and rats.

1952 • 638 citations

SODIUM DIPHENYL HYDANTOINATE IN THE TREATMENT OF CONVULSIVE DISORDERS

1938 • 451 citations

Experimental Determination of the Anticonvulsant Properties of Some Phenyl Derivatives

1937 • 303 citations

Experimental Models of Epilepsy: A Manual for the Laboratory Worker.

1973 • 262 citations

Pharmacological and clinical studies on Valium (T.M.) a new psychotherapeutic agent of the benzodiazepine class.

1961 • 242 citations

Mechanisms of Action of Antiepileptic Drugs

2007 • 213 citations

Laboratory Evaluation of Antiepileptic Drugs

1969 • 189 citations

Comparative assay of an antiepileptic drugs by psychomotor seizure test and minimal electroshock threshold test.

1953 • 142 citations

Timed Intravenous Infusion of Metrazol and Strychnine for Testing Anticonvulsant Drugs.

1949 • 130 citations

The Developing Animal as a Model

1969 • 120 citations

Anticonvulsant properties of some benzodiazepines.

1966 • 114 citations

Laboratory assay of clinically effective antiepileptic drugs*,††This investigation was supported from the Division of Research Grants and Fellowships of the National Institute of Health, U. S. Public Health Service.

1949 • 104 citations

Comparison of maximal seizures evoked by pentylenetetrazol (metrazol) and electroshock in mice, and their modification by anticonvulsants.

1953 • 104 citations

Antiepileptic Drug Development: I. History and a Program for Progress

1978 • 97 citations

Anticonvulsant Activity and Toxicity of Phensuximide, Methsuximide and Ethosuximide

1963 • 68 citations

Anticonvulsant properties of 5-phenyl-5-ethyl-hexahydropyrimidine-4,6-dione (mysoline), a new antiepileptic.

1953 • 44 citations

The search for new drugs against epilepsy.

1952 • 43 citations

Untersuchungen über die Wirkung einiger Arzneimittel auf die Erregbarkeit des Grosshirns nebst Beiträgen zur Therapie der Epilepsie

1882 • 41 citations

Anticonvulsants. I. Dibenzo[a,d]cycloheptadiene-5-carboxamide and Related Compounds

1964 • 35 citations

Evaluation of Five Methods for Testing Anticonvulsant Activities

1954 • 34 citations

Anticonvulsant semicarbazides

1968 • 32 citations

THE PREDICTABLE VALUE OF ANTICONVULSANT INDICES

1956 • 26 citations

Classification of CNS drugs by a mouse screening battery.

1961 • 25 citations

ANTICONVULSANT PROPERTIES OF CHLORDIAZEPOXIDE, DIAZEPAM AND CERTAIN OTHER 1,4-BENZODIAZEPINES.

1965 • 22 citations

A comparison of the anticonvulsant, neurotoxic and lethal effects of diphenylbarbituric acid, phenobarbital and diphenylhydantoin in the mouse.

1973 • 21 citations

Anticonvulsant Properties of Some N-Substituted Hydantoins

1962 • 16 citations

Anticonvulsants. 4. Metharbital and phenobarbital derivatives

1973 • 14 citations

Anticonvulsant drugs; mechanisms of action and methods of assay.

1949 • 13 citations

Anticonvulsants

1964 • 12 citations

Anticonvulsants. 3. Phenobarbital and mephobarbital derivatives

1973 • 12 citations

Evaluation of a new convulsant for anticonvulsant screening.

1967 • 12 citations

Laboratory technics for the identification and evaluation of potentially antiepileptic drugs.

1945 • 6 citations

Drug Contamination of Mortars and Pestles

1978 • 4 citations

Résultats expérimentaux et cliniques obtenus au moyen de quelques substances anti-épileptiques récentes

1957 • 3 citations

Synthesis and Anticonvulsant Properties of Some Derivatives of N-Methyl-2-phenylsuccinimide II

1970 • 3 citations

CERTAIN PHARMACOLOGICAL PROPERTIES OF 3-ETHYL-2-METHYL-2-PHENYLSUCCINIMIDE.

1964 • 1 citations