Dissimilar evolution of B‐locus versus A‐locus and class II loci of the HLA region in South American Indian tribes

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

The sampling theory of selectively neutral alleles

1972 • 2,158 citations

Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection

1988 • 1,968 citations

Histocompatibility Testing

1971 • 1,937 citations

MHC ligands and peptide motifs: first listing

1995 • 1,674 citations

Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 Å resolution

1991 • 1,079 citations

Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection.

1989 • 893 citations

Reconstruction of human evolution: bringing together genetic, archaeological, and linguistic data.

1988 • 881 citations

THE HOMOZYGOSITY TEST OF NEUTRALITY

1978 • 689 citations

Allelic genealogy under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci.

1990 • 688 citations

Population Biology of Antigen Presentation by MHC Class I Molecules

1996 • 652 citations

Molecular analysis of the association of HLA-B53 and resistance to severe malaria

1992 • 645 citations

Map of the human MHC

1993 • 585 citations

A BIOLOGICAL ROLE FOR THE MAJOR HISTOCOMPATIBILITY ANTIGENS

1975 • 488 citations

Polymorphism, recombination, and linkage disequilibrium within the HLA class II region.

1992 • 416 citations

HLA-A and B polymorphisms predate the divergence of humans and chimpanzees

1988 • 341 citations

Bone Marrow–Allograft Rejection by T Lymphocytes Recognizing a Single Amino Acid Difference in HLA-B44

1990 • 338 citations

Locus‐specific amplification of HLA class I genes from genomic DNA: locus‐specific sequences in the first and third introns of HLA‐A, ‐B, and ‐C alleles

1995 • 302 citations

Unusual HLA-B alleles in two tribes of Brazilian Indians

1992 • 288 citations

Positive Darwinian selection promotes charge profile diversity in the antigen-binding cleft of class I major-histocompatibility-complex molecules.

1990 • 287 citations

Evolution of Class-I MHC Genes and Proteins: From Natural Selection to Thymic Selection

1990 • 286 citations

MHC polymorphism pre-dating speciation

1988 • 273 citations

Nomenclature for Factors of the HLA System, 1995

1995 • 265 citations

Practical, biochemical and evolutionary implications of the discovery of HLA class I supermotifs

1996 • 263 citations

Nomenclature for factors of the HLA system. 1995

1995 • 254 citations

New recombinant HLA-B alleles in a tribe of South American Amerindians indicate rapid evolution of MHC class I loci

1992 • 251 citations

Mutations and selection in the generation of class II histocompatibility antigen polymorphism.

1984 • 232 citations

The Antigen-Specific, Major Histocompatibility Complex-Restricted Receptor on T Cells

1986 • 225 citations

Diversity and diversification of HLA-A,B,C alleles.

1989 • 224 citations

Histocompatibility Testing

2000 • 219 citations

Polymorphism and balancing selection at major histocompatibility complex loci.

1992 • 204 citations

Definition of an HLA-A3-like supermotif demonstrates the overlapping peptide-binding repertoires of common HLA molecules

1996 • 201 citations

Several HLA alleles share overlapping peptide specificities.

1995 • 197 citations

The T-cell repertoire for antigen and MHC

1988 • 180 citations

Map of the human MHC

1991 • 174 citations

Distinctive polymorphism at the HLA-C locus: implications for the expression of HLA-C.

1992 • 172 citations

Alleles at four HLA class II loci determined by oligonucleotide hybridization and their associations in five ethnic groups

1991 • 169 citations

DNA typing for class II HLA antigens with allele-specific or group-specific amplification III. Typing for 24 alleles of HLA-DP

1991 • 155 citations

Differences in HLA class II alleles of isolated South American Indian populations from Brazil and Argentina

1993 • 131 citations

GENETIC CONTROL OF SURVIVAL IN EPIDEMICS

1979 • 114 citations

A method for typing polymorphism at the HLA‐A locus using PCR amplification and immobilized oligonucleotide probes

1994 • 108 citations

The set of naturally processed peptides displayed by DR molecules is tuned by polymorphism of residue 86

1993 • 107 citations

Heterozygosity at individual amino acid sites: extremely high levels for HLA-A and -B genes.

1991 • 102 citations

Analysis of HLA class II haplotypes in the Cayapa Indians of Ecuador: a novel DRB1 allele reveals evidence for convergent evolution and balancing selection at position 86.

1994 • 102 citations

A uniquely high level of recombination at the HLA-B locus.

1994 • 101 citations

DNA typing for class II HLA antigens with allele-specific or group-specific amplification. I. Typing for subsets of HLA-DR4

1990 • 96 citations

HLA‐B15: A widespread and diverse family of HLA‐B alleles

1994 • 93 citations

DNA typing for HLA class I alleles: I. Subsets of HLA-A2 and of -A28

1992 • 85 citations

Episodic evolution and turnover of HLA‐B in the indigenous human populations of the Americas

1997 • 84 citations

Major histocompatibility complex class II alleles and haplotypes and blood groups of four Amerindian tribes of Northern Colombia

1994 • 82 citations

High Rate of Infection with the Human T-Cell Leukemia Retrovirus Type II in Four Indian Populations of Argentina

1993 • 80 citations

Population diversity of B‐locus alleles observed by high‐resolution DNA typing

1995 • 71 citations

HLA class II haplotypes in Amerindians and in black North and South Americans*

1991 • 70 citations

HLA-DR and -DQ gene polymorphism in West Africans is twice as extensive as in north European Caucasians: evolutionary implications.

1991 • 65 citations

DNA typing for class II HLA antigens with allele-specific or group-specific amplification. IV. Typing for alleles of the HLA-DR2 group

1991 • 63 citations

DNA typing for class II hla antigens with allele-specific or group-specific amplification. II. typing for alleles of the DRw52-associated group

1990 • 63 citations

Serologic cross-reactivities poorly reflect allelic relationships in the HLA-B12 and HLA-B21 groups. Dominant epitopes of the alpha 2 helix.

1992 • 61 citations

Contrasting roles of interallelic recombination at the HLA-A and HLA-B loci.

1993 • 58 citations

Characterization of the HLA-A polymorphism by locus-specific polymerase chain reaction amplification and oligonucleotide hybridization

1994 • 51 citations

Mysteries of the Amerindians

1981 • 48 citations

Restriction and persistence of polymorphisms of HLA and other blood genetic traits in the Parakanã Indians of Brazil

1980 • 48 citations

Genetic diversity within the HLA Class II region: Ten new DPB1 alleles and their population distribution

1992 • 46 citations

DNA typing for class II HLA antigens with allele-specific or group-specific amplification

1991 • 43 citations

HLA-B alleles of the Cayapa of Ecuador: new B39 and B15 alleles

1995 • 43 citations

South American Indians: a case study in evolution

1989 • 40 citations

Molecular definition of an elusive third HLA-A9 molecule: HLA-A9.3

1992 • 39 citations

Structure of the HLA-A*0204 antigen, found in South American Indians. Spatial clustering of HLA-A2 subtype polymorphism

1991 • 39 citations

Specificity of the T Cell Receptor for Antigen

1988 • 34 citations

Histocompatibility antigens in a genetically isolated American indian tribe.

1973 • 32 citations

A new HLA-B15 allele (B * 1522) found in Bari-Motilones Amerindians in Venezuela: comparison of its intron 2 sequence with those of B * 1501 and B * 3504

1995 • 31 citations

A small test of a sequence‐based typing method: Definition of the B*1520 allele

1994 • 30 citations

Disequilibrium Pattern Analysis. I. Theory

1987 • 30 citations

A comprehensive polymerase chain reaction-oligonucleotide typing system for the HLA class I A locus

1994 • 30 citations

A novel subtype of A2 (A*0217) isolated from the South American Indian B‐cell line AMALA

1995 • 30 citations

Of HLA, tryps, and selection: An essay on coevolution of MHC and parasites

1991 • 28 citations

Microheterogeneity in HLA-B35 alleles influences peptide-dependent allorecognition by cytotoxic T cells but not binding of a peptide-restricted monoclonal antibody

1993 • 28 citations

Allelic variations clustered in the antigen binding sites of HLA-Bw62 molecules

1993 • 27 citations

A new HLA-B35 allele (B * 3510) found in isolated Jaidukama South American Indians

1995 • 27 citations

HLA‐B16 antigens: sequence of the ST‐16 antigen, further definition of two B38 subtypes and evidence for convergent evolution of B*3902

1995 • 27 citations

The Histocompatibility System in the Warao Indians of Venezuela

1976 • 26 citations

Primary structure of a novel HLA‐B39 allele (B*3909) from the Warao Indians of Venezuela. Further evidence for local HLA‐B diversification in South America

1995 • 26 citations

A Model for T Cell Receptor and MHC/Peptide Interaction

1989 • 26 citations

The Great Journey: The Peopling of Ancient America

1988 • 25 citations

HLA-B40, B18, B27, and B37 allele discrimination using group-specific amplification and SSCP method

1996 • 24 citations

HLA polymorphism in a Mataco South American Indian tribe: Serology of class I and II antigens

1992 • 21 citations

A novel HLA-DRB1 allele (DRB1*0417) in South American Indians

1993 • 21 citations

Novel HLA‐B alleles, B*8201, B*3515 and B*5106, add to the complexity of serologic identification of HLA types

1996 • 21 citations

A newHLA-B35 (B * 3516) allele found in a Mexican of Nahua (Aztec) descent

1996 • 20 citations

Description of a novel HLA-B35 (B∗3514) allele found in a mexican family of Nahua Aztec descent

1996 • 19 citations

DQA1∗03 subtypes have different associations with DRB1 and DQB1 alleles

1994 • 19 citations

FREQUENCIES OF HLA‐A24 AND HLA‐DR4‐DQ8 ARE INCREASED AND THAT OF HLA‐B BLANK IS DECREASED IN CHRONIC TOXIC OIL SYNDROME

1996 • 18 citations

A rapid and sensitive method of identification of HTLV‐II subtypes

1995 • 18 citations

HLA‐B alleles of the Navajo: no evidence for rapid evolution in the Nadene

1996 • 17 citations

The Distribution of HLA Antigens in the Motilones Indians of Venezuela

1978 • 16 citations

A new HLA-DR6 allele (DRB1 * 1413) found in a tribe of Brazilian Indians

1994 • 16 citations

Three new HLA‐B alleles found in Mexican‐Americans

1995 • 16 citations

Identification of a novel HLA‐B40 allele (B*4008) in a patient with leukemia

1995 • 14 citations

Complete sequence of a new HLA-B35 allele found in a tribe of Mapuche Indians in the south of Argentina

1996 • 11 citations

The Nature of Selection in the HLA Region Based on Population Data From the Ninth Workshop

1984 • 11 citations

Report of the North American Indian anthropology section

1992 • 10 citations

Full cDNA of a novel HLA‐B39 subtype, B*39061

1996 • 9 citations

New Alleles of the HLA-B15 Family

1997 • 6 citations

Evidence for balancing selection at peptide binding pockets of HLA-B locus

1995 • 1 citations