Of HLA, tryps, and selection: An essay on coevolution of MHC and parasites

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

1987 • 59,130 citations

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Bacterial evolution

1987 • 2,303 citations

Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection

1988 • 1,968 citations

Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection.

1989 • 893 citations

Genetic Basis for Species Vulnerability in the Cheetah

1985 • 878 citations

Allelic genealogy under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci.

1990 • 688 citations

A clonal theory of parasitic protozoa: the population structures of Entamoeba, Giardia, Leishmania, Naegleria, Plasmodium, Trichomonas, and Trypanosoma and their medical and taxonomical consequences.

1990 • 567 citations

The Trypanosomes of Mammals

1973 • 544 citations

A BIOLOGICAL ROLE FOR THE MAJOR HISTOCOMPATIBILITY ANTIGENS

1975 • 488 citations

Natural populations of Trypanosoma cruzi, the agent of Chagas disease, have a complex multiclonal structure.

1986 • 407 citations

Die Konstitution des normalen adulten Humanhämoglobins

1961 • 386 citations

HLA-A and B polymorphisms predate the divergence of humans and chimpanzees

1988 • 341 citations

Evolution of the major histocompatibility complex.

1986 • 326 citations

Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis.

1989 • 310 citations

Periodic Selection in Escherichia Coli

1951 • 301 citations

The DNA sequence of the H-2kb gene: evidence for gene conversion as a mechanism for the generation of polymorphism in histocompatibilty antigens.

1983 • 280 citations

MHC polymorphism pre-dating speciation

1988 • 273 citations

ISOZYME VARIABILITY INTRYPANOSOMA CRUZI, THE AGENT OF CHAGAS' DISEASE: GENETICAL, TAXONOMICAL, AND EPIDEMIOLOGICAL SIGNIFICANCE

1988 • 259 citations

A molecular map of the chicken major histocompatibility complex: the class II beta genes are closely linked to the class I genes and the nucleolar organizer.

1988 • 259 citations

Cloning and complete sequence of an HLA-A2 gene: analysis of two HLA-A alleles at the nucleotide level.

1985 • 255 citations

Nucleotide sequences of chimpanzee MHC class I alleles: evidence for trans-species mode of evolution.

1988 • 240 citations

Population Genetics and Molecular Evolution

2020 • 215 citations

Isozyme Variability in Trypanosoma cruzi, The Agent of Chagas' Disease: Genetical, Taxonomical, and Epidemiological Significance

1988 • 206 citations

GENERAL CONCEPTS ON THE EVOLUTIONARY BIOLOGY OF PARASITES

1977 • 202 citations

Biology and physiology of the lower Trypanosomatidae

1980 • 158 citations

Evolution of the MHC class I genes of a New World primate from ancestral homologues of human non-classical genes

1990 • 147 citations

Evolution of the major histocompatibility complex

1986 • 142 citations

Nucleotide Sequence of a Light Chain Gene of the Mouse I-A Subregion: Aβ ^d

1983 • 127 citations

The origin of MHC class II gene polymorphism within the genus Mus

1988 • 126 citations

Shared class II MHC polymorphisms between humans and chimpanzees

1989 • 121 citations

Are Invertebrates Capable of Anticipatory Immune Responses?

1989 • 120 citations

Evolution of parasitism: kinetoplastid protozoan history reconstructed from mitochondrial rRNA gene sequences.

1988 • 114 citations

Structural analysis of peptides capable of binding to more than one Ia antigen.

1989 • 112 citations

Isolation of chicken major histocompatibility complex class II (B-L) beta chain sequences: comparison with mammalian beta chains and expression in lymphoid organs.

1988 • 109 citations

Investigation of genetic diversity in wild colonies of naked mole‐rats (Heterocephalus glaber) by DNA fingerprinting

1990 • 78 citations

Limited MHC polymorphism in whales

1989 • 77 citations

General Concepts on the Evolutionary Biology of Parasites

1977 • 75 citations

A primate species with limited major histocompatibility complex class I polymorphism.

1988 • 66 citations

DNA contents and molecular karyotypes of hybrid Trypanosoma brucei

1987 • 58 citations

Globin evolution in the genusXenopus: Comparative analysis of cDNAs coding for adult globin polypeptides ofXenopus borealis andXenopus tropicalis

1986 • 56 citations

A clonal theory of parasitic protozoa: The population structures of Entamoeba, Giardia, Leishmania, Naegleria, Plasmodium, Trichomonas, and Trypanosoma and their medical and taxonomical consequences

1990 • 52 citations

HLA-B37 and HLA-A2.1 molecules bind largely nonoverlapping sets of peptides.

1990 • 47 citations

Specificity of peptide binding by the HLA-A2.1 molecule.

1989 • 45 citations

Mhc-DRB genes of the pigtail macaque (Macaca nemestrina): implications for the evolution of human DRB genes.

1991 • 42 citations

Hämogiobine,XXXV^{<b />}. Die Sequenz der β_A- und ß_B-Ketten der Hämoglobine des Karpfens(Cyprinus carpioL.)

1980 • 37 citations

On the anomalous nature of the major histocompatibility complex in Syrian hamsters, Hm-1.

1983 • 30 citations

Limited polymorphism of both classes of MHC genes in four different species of the Balkan mole rat

1988 • 26 citations

Coupled Evolution: Adaptive Interactions among the Genomes of Plasmids, Viruses, and Cells

1959 • 24 citations

Phylogeny of primate major histocompatibility complex DRB alleles

1991 • 12 citations

Peptic Peptides from the β Polypeptide Chain of All Component of Chicken Hemoglobin1

1975 • 5 citations

Tryptic Peptides from the β Polypeptide Chain of All Component of Chicken Hemoglobin1

1975 • 4 citations