Biochemical Characterization of Lucigenin (Bis-N-methylacridinium) as a Chemiluminescent Probe for Detecting Intramitochondrial Superoxide Anion Radical Production

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Oxidative Stress, Caloric Restriction, and Aging

1996 • 3,136 citations

Biology of disease: free radicals and tissue injury.

1982 • 3,078 citations

Oxidative damage and mitochondrial decay in aging.

1994 • 2,024 citations

Mitogenic Signaling Mediated by Oxidants in Ras-Transformed Fibroblasts

1997 • 1,582 citations

Oxidative Stress in Neurodegenerative Diseases

1996 • 1,336 citations

Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy.

1981 • 913 citations

Uncoupling: new approaches to an old problem of bioenergetics

1998 • 877 citations

Respiratory chain linked H₂O₂ production in pigeon heart mitochondria

1971 • 544 citations

Validation of Lucigenin (Bis-N-methylacridinium) as a Chemilumigenic Probe for Detecting Superoxide Anion Radical Production by Enzymatic and Cellular Systems

1998 • 526 citations

Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow.

1993 • 518 citations

A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

1998 • 497 citations

Implication of Mitochondrial Hydrogen Peroxide Generation in Ceramide-induced Apoptosis

1997 • 485 citations

[57] Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria

1984 • 477 citations

[36] Phagocytic leukocyte oxygenation activities and chemiluminescence: A kinetic approach to analysis

1986 • 462 citations

Chapter 26 Preparation and Characterization of Mitochondria and Submitochondrial Particles of Rat Liver and Liver-Derived Tissues

1978 • 451 citations

Mitochondria: a practical approach.

1987 • 412 citations

Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo.

1994 • 403 citations

Do Nitroxide Antioxidants Act as Scavengers of <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif"><mml:mrow><mml:msubsup><mml:mtext>O</mml:mtext><mml:mn>2</mml:mn><mml:munder><mml:mo>−</mml:mo><mml:mo>˙</mml:mo></mml:munder></mml:msubsup></mml:mrow></mml:math>or as SOD Mimics?

1996 • 341 citations

Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug.

1996 • 312 citations

Mitochondria: A practical approach

1988 • 307 citations

Substrate and Site Specificity of Hydrogen Peroxide Generation in Mouse Mitochondria

1998 • 237 citations

Lucigenin (Bis-N-methylacridinium) as a Mediator of Superoxide Anion Production

1997 • 220 citations

[39] The generation of chemiluminescence (CL) by phagocytic cells

1978 • 215 citations

Redox-regulated Signaling by Lactosylceramide in the Proliferation of Human Aortic Smooth Muscle Cells

1997 • 202 citations

Complete inhibition of electron transfer from ubiquinol to cytochrome b by the combined action of antimycin and myxothiazol

1981 • 149 citations

Detection of mitochondria-derived reactive oxygen species production by the chemilumigenic probes lucigenin and luminol

1999 • 142 citations

Chemiluminescence Induced by Operation of Iron-Flavoproteins^*

1962 • 109 citations

Oxygen Radicals and the Disease Process

1998 • 108 citations

The mitochondrion in health and disease

1993 • 100 citations

Further evidence that lucigenin-derived chemiluminescence monitors mitochondrial superoxide generation in rat alveolar macrophages

1994 • 95 citations

Detergent-amplified chemiluminescence of lucigenin for determination of superoxide anion production by NADPH oxidase and xanthine oxidase

1988 • 83 citations

THE QUANTUM YIELD OF THE CHEMILUMINESCENCE OF DIMETHYLBIACRIDYLIUM NITRATE AND THE MECHANISM OF ITS ENZYMICALLY INDUCED CHEMILUMINESCENCE*

1964 • 63 citations

Lucigenin chemiluminescence and its relationship to mitochondrial respiration in phagocytic cells

1989 • 17 citations

Comparison of oxidant-generation and BP-diol activation by bone marrow cells from and mice: Implications for risk of bone marrow toxicity induced by polycyclic hydrocarbons

1992 • 17 citations

Tumor suppression by manganese superoxide dismutase

1996 • 4 citations