Detection of mitochondria-derived reactive oxygen species production by the chemilumigenic probes lucigenin and luminol

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Oxidative Stress, Caloric Restriction, and Aging

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The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

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A model for p53-induced apoptosis

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Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

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Oxidative Stress in Neurodegenerative Diseases

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Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

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Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy.

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Uncoupling: new approaches to an old problem of bioenergetics

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Respiratory chain linked H₂O₂ production in pigeon heart mitochondria

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Validation of Lucigenin (Bis-N-methylacridinium) as a Chemilumigenic Probe for Detecting Superoxide Anion Radical Production by Enzymatic and Cellular Systems

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Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow.

1993 • 518 citations

A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

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Implication of Mitochondrial Hydrogen Peroxide Generation in Ceramide-induced Apoptosis

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Chapter 26 Preparation and Characterization of Mitochondria and Submitochondrial Particles of Rat Liver and Liver-Derived Tissues

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Mitochondria: a practical approach.

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Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo.

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Luminol and lucigenin as detectors for O2ṡ−

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Do Nitroxide Antioxidants Act as Scavengers of <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif"><mml:mrow><mml:msubsup><mml:mtext>O</mml:mtext><mml:mn>2</mml:mn><mml:munder><mml:mo>−</mml:mo><mml:mo>˙</mml:mo></mml:munder></mml:msubsup></mml:mrow></mml:math>or as SOD Mimics?

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Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes

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[24] Use of specific inhibitors on the mitochondrial bc1 complex

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Superoxide Radical and Hydrogen Peroxide in Mitochondria

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Substrate and Site Specificity of Hydrogen Peroxide Generation in Mouse Mitochondria

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Lucigenin (Bis-N-methylacridinium) as a Mediator of Superoxide Anion Production

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[39] The generation of chemiluminescence (CL) by phagocytic cells

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The mitochondrial site of superoxide formation

1986 • 208 citations

Chemiluminescence detection of H2O2 produced by human neutrophils during the respiratory burst

1987 • 148 citations

Reactive Oxygen Species Produced by Liver Mitochondria of Rats in Sepsis

1995 • 145 citations

Further evidence that lucigenin-derived chemiluminescence monitors mitochondrial superoxide generation in rat alveolar macrophages

1994 • 95 citations

Hepatocyte injury resulting from the inhibition of mitochondrial respiration at low oxygen concentrations involves reductive stress and oxygen activation

1995 • 56 citations

Comparison of oxidant-generation and BP-diol activation by bone marrow cells from and mice: Implications for risk of bone marrow toxicity induced by polycyclic hydrocarbons

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Lucigenin chemiluminescence and its relationship to mitochondrial respiration in phagocytic cells

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Tumor suppression by manganese superoxide dismutase

1996 • 4 citations