Dysplasia and early carcinoma in inflammatory bowel disease and colorectal adenomas

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

Mutations of Chromosome 5q21 Genes in FAP and Colorectal Cancer Patients

1991 • 1,890 citations

Dysplasia in inflammatory bowel disease: Standardized classification with provisional clinical applications

1983 • 1,856 citations

Localization of the gene for familial adenomatous polyposis on chromosome 5

1987 • 1,386 citations

The Spread of Rectal Cancer and its Effect on Prognosis

1958 • 807 citations

Prognostic factors in colorectal carcinomas arising in adenomas: Implications for lesions removed by endoscopic polypectomy

1985 • 721 citations

The Gene for Familial Polyposis Coli Maps to the Long Arm of Chromosome 5

1987 • 683 citations

Carcinoma of the Colon and Rectum

1962 • 582 citations

Rectal biopsy as an aid to cancer control in ulcerative colitis.

1967 • 580 citations

Chromosome 5 allele loss in human colorectal carcinomas

1987 • 566 citations

Dysplasia-associated lesion or mass (DALM) detected by colonoscopy in long-standing ulcerative colitis: An indication for colectomy

1981 • 562 citations

DNA aneuploidy in colonic biopsies predicts future development of dysplasia in ulcerative colitis

1992 • 554 citations

Colorectal cancer risk and mortality in patients with ulcerative colitis

1992 • 504 citations

Precancer and cancer in extensive ulcerative colitis: findings among 401 patients over 22 years.

1990 • 454 citations

Small “flat adenoma” of the large bowel with special reference to its clinicopathologic features

1985 • 425 citations

Histopathology and prognosis of malignant colorectal polyps treated by endoscopic polypectomy.

1984 • 383 citations

Colonoscopic surveillance reduces mortality from colorectal cancer in ulcerative colitis

1993 • 351 citations

Cancer in universal and left-sided ulcerative colitis: Factors determining risk

1979 • 350 citations

Proctosigmoidoscopy and polypectomy in reducing the incidence of rectal cancer

1974 • 345 citations

Familial Polyposis Coli. Family Studies, Histopathology, Differential Diagnosis, and Results of Treatment.

1975 • 300 citations

Neoplastic progression in ulcerative colitis: Histology, DNA content, and loss of a p53 allele

1992 • 280 citations

Surveillance for colonic carcinoma in ulcerative colitis

1985 • 268 citations

Prevalence and malignant potential of colorectal polyps in asymptomatic, average-risk men.

1991 • 247 citations

Flat adenomas of the colon

1991 • 226 citations

Incomplete sulphomucin-secreting intestinal metaplasia for gastric cancer. Preliminary data from a prospective study from three centres.

1985 • 199 citations

Colonoscopic surveillance in long-standing total ulcerative colitis—A 15-year follow-up study

1990 • 198 citations

Surveillance in the routine management of ulcerative colitis: The predictive value of low-grade dysplasia

1992 • 197 citations

Distribution of human colonic lymphatics in normal, hyperplastic, and adenomatous tissue. Its relationship to metastasis from small carcinomas in pedunculated adenomas, with two case reports.

1973 • 196 citations

When is endoscopic polypectomy adequate therapy for colonic polyps containing invasive carcinoma?

1986 • 194 citations

Distribution of Human Colonic Lymphatics in Normal, Hyperplastic, and Adenomatous Tissue

1973 • 179 citations

Familial Polyposis Coli. Family Studies, Histopathology, Differential Diagnosis, and Results of Treatment

1976 • 177 citations

Surgical pathology of endoscopically removed malignant polyps of the colon and rectum

1983 • 175 citations

Comparative electron microscopic features of normal, hyperplastic, and adenomatous human colonic epithelium. Variations in cellular structure relative to the process of epithelial differentiation.

1973 • 169 citations

Comparative Electron Microscopic Features of Normal, Hyperplastic, and Adenomatous Human Colonic Epithelium

1973 • 167 citations

Loss of heterozygosity affecting the p53, Rb, and mcc/apc tumor suppressor gene loci in dysplastic and cancerous ulcerative colitis.

1992 • 159 citations

C-Ki-ras mutations in chronic ulcerative colitis and sporadic colon carcinoma

1990 • 150 citations

Dysplasia in chronic ulcerative colitis

1992 • 149 citations

Minute adenomatous and hyperplastic polyps of the colon: divergent patterns of epithelial growth with specific associated mesenchymal changes. Contrasting roles in the pathogenesis of carcinoma.

1971 • 143 citations

Minute Adenomatous and Hyperplastic Polyps of the Colon: Divergent Patterns of Epithelial Growth with Specific Associated Mesenchymal Changes

1971 • 132 citations

Comparative Electron-Microscopic Features of Normal, Hyperplastic, and Adenomatous Human Colonic Epithelium

1975 • 125 citations

Crohnʼs Disease-Associated Carcinoma

1989 • 119 citations

Flat Adenomas in a Colon Cancer-Prone Kindred1

1988 • 119 citations

Clinicopathologic features of the flat adenoma

1991 • 118 citations

Tumors of the intestines

2003 • 116 citations

Correlations between rectal mucosa cell proliferation and the clinical and pathological features of nonfamilial neoplasia of the large intestine.

1991 • 114 citations

Colon cancer surveillance in chronic ulcerative colitis: historical cohort study.

1990 • 114 citations

Colorectal adenomas and cancer: pathologic relationships.

1982 • 108 citations

Significance of venous and lymphatic invasion in malignant polyps of the colon and rectum.

1989 • 105 citations

Activation of c-Ki-ras in human gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products.

1990 • 100 citations

Dysplasia and carcinoma in longstanding ulcerative colitis: an endoscopic and histological surveillance programme.

1991 • 97 citations

The histologic appearance of dysplasia (precarcinomatous change) in Crohn's disease of the small and large intestine

1981 • 96 citations

Epidemiologic characteristics of the flat adenoma of muto

1992 • 91 citations

Flat adenoma and flat mucosal carcinoma (IIb type)— A new precursor of colorectal carcinoma?

1988 • 74 citations

Rectal epithelial cell proliferation patterns as predictors of adenomatous colorectal polyp recurrence.

1993 • 69 citations

Colonic “precancer” in Crohn's disease

1981 • 66 citations

Frequent Loss of a p53 Allele in Carcinomas and their Precursors in Ulcerative Colitis

1991 • 62 citations

c-Ki-ras mutations in dysplastic fields and cancers in ulcerative colitis

1992 • 56 citations

Epithelial misplacement in adenomatous polyps of the colon and rectum

1974 • 56 citations

Malignant colon polyps--cure by colonoscopy or colectomy?

1984 • 53 citations

Crohn's colitis with carcinoma and dysplasia. Report of a case and review of 100 small and large bowel resections for Crohn's disease to detect incidence of dysplasia.

1983 • 52 citations

New Colon Cancer Gene Discovered

1993 • 46 citations

Value of mucin histochemistry in follow up surveillance of patients with long standing ulcerative colitis.

1986 • 44 citations

Expression of intestinal mucin antigens in the gastric epithelium and its relationship with malignancy

1988 • 44 citations

Crohnʼs colitis with carcinoma and dysplasia

1983 • 44 citations

Rectal mucosal dysplasia in Crohn's disease.

1990 • 43 citations

Defining the Precursor Tissue of Ordinary Large Bowel Carcinoma: Implications for Cancer Prevention

1978 • 43 citations

Adenomatous epithelium, intraepithelial anaplasia, and invasive carcinoma in ulcerative colitis

1973 • 40 citations

The significance of diminutive colonic polyps found at flexible sigmoidoscopy

1989 • 39 citations

Tumor‐associated glycoprotein (TAG‐72) expression in ulcerative colitis

1989 • 38 citations

INVASIVE CARCINOMA OF THE LARGE INTESTINE: A PREVENTABLE DISEASE?

1965 • 37 citations

An immunoperoxidase study of epithelial marker antigens in ulcerative colitis with dysplasia and carcinoma.

1985 • 34 citations

Immunohistologic Study of Ulcerative Colitis With Monoclonal Antibodies Against Tumor-Associated and/or Differentiation Antigens

1988 • 30 citations

Studies on the Thomsen-Friedenreich antigen in human colon with the lectin Amaranthin. Normal and neoplastic epithelium express only cryptic T antigen.

1992 • 29 citations

Tissue carcinoembryonic antigen and dna aneuploidy in precancerous and cancerous colorectal lesions

1990 • 29 citations

Pseudoinvasion with High-Grade Dysplasia in a Colonic Adenoma

1990 • 26 citations

Adenocarcinoma of the small intestine arising in crohn's disease: Demonstration of a tumor‐associated antigen in invasive and intraepithelial components

1975 • 25 citations

Crohnʼs Disease with Adenocarcinoma and Dysplasia

1989 • 22 citations

Expression of carcinoembryonic antigen, T-antigen, and oncogene products as markers of neoplastic and preneoplastic colonic mucosa

1987 • 22 citations

Adenomatous Polyp with Submucosal Cysts

1973 • 21 citations

Colitis cystica profunda in an adenoma (adenomatous polyp)

1970 • 18 citations

Lectin staining of neoplastic and normal background colorectal mucosa in nonpolyposis and polyposis patients

1991 • 16 citations

Distribution of Ha-ras alleles in patients with colorectal cancer and Crohn's disease.

1991 • 14 citations

Cytonuclear morphometry in assesment of dysplasia in polyps Pilot study

1992 • 13 citations

ras and c-myc protein expression in colorectal carcinoma

1992 • 13 citations

Variable expression of P-glycoprotein in normal, inflamed, and dysplastic areas in ulcerative colitis

1992 • 12 citations

Quantitative cytochemical detection of malignant and potentially malignant cells in the colon.

1990 • 12 citations

Endoscopic large bowel polypectomy

1985 • 12 citations

Pathology of the Colon, Small Intestine and Anus

1992 • 8 citations

The incidence and carbohydrate histochemistry of dystrophic goblet cells in colon.

1988 • 3 citations

DNA ploidy of colorectal cancer and synchronous polyps in polyposis coli

1991 • 3 citations

The detection of dysplasias in ulcerative colitis by a monoclonal antibody: preliminary report.

1988 • 2 citations