Expression of carcinoembryonic antigen, T-antigen, and oncogene products as markers of neoplastic and preneoplastic colonic mucosa

DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES

1965 • 2,318 citations

The evolution of cancer of the colon and rectum

1975 • 2,120 citations

Mechanism of activation of a human oncogene

1982 • 1,417 citations

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1982 • 1,398 citations

The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes

1981 • 736 citations

Familial Polyposis Coli

2008 • 506 citations

A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells

1983 • 485 citations

Crohn's Disease and Cancer

1973 • 473 citations

Oncogenes in solid human tumours

1982 • 467 citations

Alterations in human colonic mucin occurring with cellular differentiation and malignant transformation.

1982 • 331 citations

Do Adenomatous Polyps of the Colon Become Malignant?

1962 • 230 citations

Monoclonal antibodies define differential ras gene expression in malignant and benign colonic diseases

1984 • 226 citations

Monoclonal antibodies of predefined specificity detect activated ras gene expression in human mammary and colon carcinomas.

1984 • 223 citations

Characterization of a human colon/lung carcinoma oncogene

1983 • 208 citations

CHRONIC ULCERATIVE COLITIS ASSOCIATED WITH MALIGNANT DISEASE

1928 • 198 citations

Small Primary Adenocarcinomas of the Colon and Rectum

1962 • 159 citations

Colon Epithelium. II. In Vivo Studies of Colon Carcinogenesis. Light Microscopic, Histochemical, and Ultrastructural Studies of Histogenesis of Azoxymethane-Induced Colon Carcinomas in Fischer 344 Rats<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref><xref ref-type="fn" rid="fn4">4</xref><xref ref-type="fn" rid="fn5">5</xref>

1981 • 86 citations

Localization and Concentration of Carcinoembryonic Antigen (CEA) in Gastrointestinal Tumors: Correlation With CEA Levels in Plasma<xref ref-type="fn" rid="fn2">2</xref>

1981 • 76 citations

The small carcinoma of the large bowel

1979 • 65 citations

The precursor tissue of ordinary large bowel cancer.

1976 • 58 citations

Comparative immunoperoxidase demonstration of T-antigens in human colorectal carcinomas and morphologically abnormal mucosa.

1985 • 57 citations

A highly sensitive method for the demonstration of carcinoembryonic antigen in normal and neoplastic colonic tissue

1978 • 57 citations

Preneoplastic and neoplastic changes in colonic mucosa in Crohn's disease.

1981 • 30 citations

Current Approach to the Polyp-Cancer Controversy

1966 • 27 citations

Microscopic intraepithelial neoplasia in large bowel mucosa

1982 • 10 citations

Carcinoma of the large intestine: Animal models and human disease

1986 • 8 citations