Distinct Biochemical Characteristics of the Two Human Profilin Isoforms

Fluorimetry study of N-(1-pyrenyl)iodoacetamide-labelled F-actin. Local structural change of actin protomer both on polymerization and on binding of heavy meromyosin.

1981 • 811 citations

Fluorimetry Study of N‐(1‐Pyrenyl)iodoacetamide‐Labelled F‐Actin

1981 • 694 citations

Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cells

1977 • 673 citations

The structure of crystalline profilin–β-actin

1993 • 662 citations

Profilins constitute a novel family of functional plant pan-allergens.

1992 • 634 citations

How profilin promotes actin filament assembly in the presence of thymosin β4

1993 • 532 citations

Regulation of Phospholipase C-γ1 by Profilin and Tyrosine Phosphorylation

1991 • 532 citations

The Actin-Binding Protein Profilin Binds to PIP ₂ and Inhibits Its Hydrolysis by Phospholipase C

1990 • 472 citations

The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells.

1992 • 285 citations

Acanthamoeba profilin interacts with G-actin to increase the rate of exchange of actin-bound adenosine 5'-triphosphate

1980 • 275 citations

Mechanism of the interaction of human platelet profilin with actin.

1991 • 235 citations

Identification of a polyphosphoinositide-binding sequence in an actin monomer-binding domain of gelsolin.

1992 • 224 citations

Interactions of gelsolin and gelsolin-actin complexes with actin. Effects of calcium on actin nucleation, filament severing, and end blocking

1985 • 208 citations

Evidence for a functional link between profilin and CAP in the yeast S. cerevisiae

1991 • 207 citations

Phosphoinositide-binding peptides derived from the sequences of gelsolin and villin.

1992 • 206 citations

Identification of a region in segment 1 of gelsolin critical for actin binding.

1990 • 205 citations

7-Chloro-4-nitrobenzeno-2-oxa-1,3-diazole actin as a probe for actin polymerization.

1981 • 203 citations

Polymerization of Acanthamoeba actin. Kinetics, thermodynamics, and co-polymerization with muscle actin.

1976 • 200 citations

The three faces of profilin

1993 • 179 citations

Poly(<scp>l</scp>‐proline)‐binding proteins from chick embryos are a profilin and a profilactin

1985 • 176 citations

Opposite effects of cofilin and profilin from porcine brain on rate of exchange of actin-bound adenosine 5'-triphosphate

1985 • 171 citations

Specificity of the interaction between phosphatidylinositol 4,5‐bisphosphate and the profilin:actin complex

1988 • 168 citations

The profilin multigene family of maize: differential expression of three isoforms

1993 • 162 citations

The use of poly(L-proline)-Sepharose in the isolation of profilin and profilactin complexes

1988 • 139 citations

The affinities of human platelet and Acanthamoeba profilin isoforms for polyphosphoinositides account for their relative abilities to inhibit phospholipase C.

1990 • 117 citations

Interaction of Profilin with G-Actin and Poly(L-Proline)

1994 • 117 citations

Simple and rapid purification of brevin

1990 • 110 citations

Mutagenesis of human profilin locates its poly(<scp>l</scp>‐prolme)‐bindmg site to a hydrophobic patch of aromatic amino acids

1993 • 108 citations

Identification of the poly-L-proline-binding site on human profilin.

1994 • 104 citations

Human profilin. Molecular cloning, sequence comparison, and chromosomal analysis.

1988 • 102 citations

Kinetic analysis of F-actin depolymerization in the presence of platelet gelsolin and gelsolin-actin complexes.

1985 • 95 citations

Characterization of renatured profilin purified by urea elution from poly‐L‐proline agarose columns

1989 • 93 citations

X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates.

1994 • 84 citations

Cloning and expression of a novel human profilin variant, profilin II

1993 • 80 citations

Dictyostelium discoideum contains two profilin isoforms that differ in structure and fuction

1991 • 73 citations

Purification and characterization of two isoforms of Acanthamoeba profilin.

1986 • 72 citations

Contractile Systems in Non‐Muscle Tissues

1977 • 69 citations

The amino acid sequence of profilin from calf spleen

1979 • 67 citations

Effect of Acanthamoeba profilin on the pre-steady state kinetics of actin polymerization and on the concentration of F-actin at steady state.

1983 • 66 citations

Elucidation of the poly‐<scp>l</scp>‐proline binding site in Acanthamoeba profilin I by NMR spectroscopy

1994 • 61 citations

Structure and function of profilin

1990 • 60 citations

[10] Affinity chromatography-based purification of profilin: Actin

1991 • 44 citations

Selective binding of gelsolin to actin monomers containing ADP

1993 • 40 citations

[9] Polyproline affinity method for purification of platelet profilin and modification with pyrene-maleimide

1991 • 39 citations

Analysis of cDNA clones for Acanthamoeba profilin‐I and profilin‐II shows end to end homology with vertebrate profilins and a small family of profilin genes

1991 • 37 citations

Identification of the functional profilin gene, its localization to chromosome subband 17p13.3, and demonstration of its deletion in some patients with Miller-Dieker syndrome.

1990 • 20 citations

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